Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038358 (
gastric ulcer
)
5,179
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The Na
+
/Ca
2+
exchanger (NCX) protein family is a part of the cation/Ca
2+
exchanger superfamily and participates in the regulation of cellular Ca
2+
homeostasis.
NCX1
, the most important subtype in the NCX family, is expressed widely in various organs and tissues in mammals and plays an especially important role in the physiological and pathological processes of nerves and the cardiovascular system. In the past few years, the function of
NCX1
in the digestive system has received increasing attention;
NCX1
not only participates in the healing process of
gastric ulcer
and gastric mucosal injury but also mediates the development of digestive cancer, acute pancreatitis, and intestinal absorption. This review aims to explore the roles of
NCX1
in digestive system physiology and pathophysiology in order to guide clinical treatments.
...
PMID:Roles of Na
+
/Ca
2+
exchanger 1 in digestive system physiology and pathophysiology. 3068 98
