Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038358 (
gastric ulcer
)
5,179
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Tumor-associated trypsin inhibitor
(
TATI
) was assayed in serum of patients with gastroenterological diseases. Of the patients 92 had gastric cancer, 50 colonic cancer, 38 colitis, 36 polyposis of the colon, and 40
gastric ulcer
. The cut-off level established on the basis of the mean concentration +3 SD of a reference population comprising 120 subjects was 32 micrograms/l. In gastric cancer
TATI
had a sensitivity and specificity similar to that of CA19-9, whereas its behavior in colon cancer was less satisfactory. Like other tumor markers
TATI
may be elevated in patients with inflammatory diseases. In our opinion
TATI
is a good tumor marker for gastric cancer and it is a useful complement to CEA and CA19-9.
...
PMID:Tumor-associated trypsin inhibitor, TATI, in gastrointestinal cancer and related benign diseases. 178 Jun 97
