Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Total 39 cases of carcinoma stomach were noticed out of 142 malignant tumours of GIT (27.46 percent). Histologically maximum cases were of diffuse type (56.41 percent) followed by intestinal type (35.89 percent) and indolent mucoid carcinoma (7.69 percent) of the stomach. The surrounding epithelium showed lot of changes in the intestinal type of carcinoma stomach. About 78.57 percent showed intestinal metaplasia, 14.28 percent of these cases showed chronic gastric ulcer and severe dysplasia (carcinoma in situ) and another 14.28 percent revealed villous adenoma with carcinoma in situ. In contrast to this, in diffuse variety, only 13.63 percent cases revealed intestinal metaplasia, 27.27 percent showed basal cell hyperplasia, stratification of the epithelium of crypts and diffuse infiltration of mucosa by malignant cells and 4.54 percent showed atrophic gastritis also. In mucoid carcinoma all cases had basal cell hyperplasia and stratification of crypts. Hence these conditions should be taken as premalignant lesions of stomach and should be cured in proper time.
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PMID:Pre-cancerous lesions of stomach. 255 96

A study was made of changes of the content of hormones (gastrin, insulin, glucagon, triodonthyronine, thyroxine, thyrotrophin, somatotrophin, adrenocorticotrophin and hydrocortisone) under the influence of standard food load in 166 patients with GIT diseases (gastric ulcer, duodenal ulcer, chronic anacid gastritis and chronic enteritis). Forty-three healthy persons entered the control group. Hormones were determined in the peripheral blood by radioimmunoassay. Taking food in healthy persons was shown to cause the stimulation of the secretion of most hormones. To elucidate the mechanisms of hormonal shifts after food load, hormones were also studied after per os intake of solutions with different pH. Disorders of postprandial reactions of the endocrine system which were specific for these nosological forms, were revealed in GIT diseases. The results of the study are of interest in view of new approaches to functional interrelationships of the GIT with endocrine glands.
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PMID:[New approaches to studying the functional relations of the gastrointestinal tract with the endocrine glands]. 408 61