Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Dysfunction of the sphincter of Oddi (SOD) is an uncommon condition which must be considered in cases of persistent pain in the upper abdomen following uncomplicated cholecystectomy, when disease in other organs, such as gastric ulcer, esophagitis and pancreatitis has been eliminated. The pathogenesis is not fully elucidated, but it is assumed that the cholecystectomy in some cases induces an increased tendency to spasm in the sphincter of Oddi (SO), and, perhaps in connection with an increased sensitivity to pressure elevations in the biliary tree, results in attacks of pain. Whether fibrosis (stenosis) of the SO due to instrumentation or passage of stones is part of the etiology is obscure. Endoscopic retrograde cholangiopancreaticography with papillary manometry should be performed in all cases where SOD is suspected. An elevated basal pressure in SO seems to be the best indicator of SOD. In cases unresponsive to conservative treatment, endoscopic sphincterotomy may be considered. This treatment is not finally evaluated, but apparently the effect is good, especially in patients with elevated basal pressure in SO. It is emphasized that the knowledge of the behavior and regulation of SO is incomplete and that this should be remembered when criteria for SOD are applied.
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PMID:[Oddi's sphincter dysfunction]. 267 55

Among 600 infants examined with ultrasound for vomiting, seven (mean age, 3 months) had distinctive features that can be considered diagnostic of gastric ulcer. The findings are thickening of the mucosa (greater than 4 mm) in the antropyloric region, elongation of the antropyloric canal, persistent spasm, and delayed gastric emptying. Two of the infants had slight thickening of the pyloric muscle. Gastrointestinal series or endoscopy demonstrated thickened gastric mucosa and a deformed gastric antrum in all infants, as well as actual ulceration in five.
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PMID:Gastric ulcer disease in infants: US findings. 329 86

The method and semeiotics of noninvasive ultrasonic diagnosis of pyloroduodenal stenosis are described. Seventy-six patients with duodenal ulcer and 13 patients with gastric ulcer were examined, and also 18 patients with gastric carcinoma and 24 healthy individuals. The echographic picture of an empty stomach in compensated pyloroduodenal stenosis did not differ from that in healthy persons, though study of the motor-evacuation activity of the stomach revealed intensified peristalsis and increased gastric half-evacuation period. In subcompensated pyloroduodenal stenosis the stomach contained fluid and the period of half-evacuation of its contents was sharply increased. All patients with decompensated pyloroduodenal stenosis had an increased volume of the stomach which contained much fluid and food remnants. Pyloric spasm was differentiated by means of the spasmolytics test. Patients with a marked periulcerous inflammatory infiltration must be kept under dynamic follow-up to evaluate the degree of the stenosis. Taking into consideration the peculiarity of the echographic picture of the pyloric part, the neoplastic character of the pyloroduodenal stenosis may be presumed with high precision.
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PMID:[Ultrasonic diagnosis of pyloroduodenal stenosis]. 763 76

Causes of unsatisfactory outcomes of pylorus preserving stomach resection are analyzed, method of prophylaxis and surgical correction is proposed. Pylorus preserving stomach resection was performed in 207 patients with chronic gastric ulcer. 2 groups of patients were compared: 166 patients who have undergone pylorus preserving stomach resection by Maky--Gorobashko (group 1); 41 patients operated according to an original method of suprapyloric stomach resection with preserving of distal Latarget nerves on serous-muscular flap formed from lesser curvature of the stomach (group 2). Of 122 examined patients of group 1 excellent and good long-term results according to Visick's criteria were achieved in 101 (82.79%), satisfactory--in 12 (9.84%), unsatisfactory--in 9 (7.37%). Bad stump evacuation due to a stable spasm of the denervated pylorus and hypokinesia of the stump were the main causes of unsatisfactory results. In group 2-39 of 41 patients were examined in long-term period. Excellent and good results were achieved in 38 patients, satisfactory--in 1. There were no unsatisfactory results.
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PMID:[Treatment of complications of pylorus preserving stomach resection]. 1200 82