Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pancreatic pseudocyst was erroneously diagnosed in three patients aged 52-57 years. Two patients had acute epigastric pain, hyperamylasemia (approximately 4,000 IU/L), and a retrogastric collection of fluid demonstrated by early ultrasonography. Laparotomy undertaken within 48 h of admission revealed the correct diagnosis in each case. One patient had perforation of a gastric ulcer into the lesser sac, and the other patient (who died) had perforation of an obstructed afferent loop 25 years after Polya partial gastrectomy. The third patient with renal failure, back pain, and marginal hyperamylasemia had a cystic mass in the lesser sac. Two internal drainage operations were performed before the correct diagnosis of epithelioid leiomyoma was established 6 years later.
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PMID:Pseudo-pseudocysts of the pancreas. 355 Jul 86

Back pain (BP) has been rated among the most important factors affecting physical health status in old age. Yet there is an under-representation of the older population in the BP literature. We present extensive interview data from the Longitudinal Study of Aging Danish Twins, dealing with a population-based sample of Danish twins aged 70-102, and describing the 1-month prevalence of BP and the development of BP over time. The associations between BP and education, self-rated health, other health problems, lifestyle factors, and physical and mental function were also investigated. Data were analysed in a cross-sectional analysis for all answers given at entry into the study and in a longitudinal analysis for participants in all four surveys. Associated factors were analysed for the cross-sectional sample using univariate and multivariate analysis accounting for the non-independence of twins in complete pairs. The overall 1-month prevalence of BP was 25% and differed significantly between men and women. The variations in prevalence between the age groups and over time were negligible. The majority of participants in all four surveys had either not experienced BP during the previous month or had done so on one occasion only. Education was not associated with BP. Self-rated health was associated with BP in a significant "dose-response" like pattern. BP was associated with bone and joint disorders, migraine headaches, lung disease, cardiovascular disorders and gastric ulcer, but not neurologic or endocrinologic diseases. BP sufferers had significantly lower scores on physical but not on mental functioning. We conclude that BP is a common symptom in old age; however, the prevalence does not change with increasing age. BP may be part of a more general syndrome of poor health among the old.
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PMID:Back pain remains a common symptom in old age. a population-based study of 4486 Danish twins aged 70-102. 1274 96

The literature data and our own studies show that in drivers of public transport vehicles, largely intensified work-related risk factors for arterial hypertension, ischemic heart disease, duodenal and gastric ulcer diseases and back pain syndrome are found. These involves occupational risk factors as well as classic ones, such as obesity, limited physical activity or tobacco smoking. Among occupational risk factors, stress induced by the responsibility for assuring public safety in heavy urban traffic, time pressure and contacts with passengers predominate. Other burdens observed in this occupational group include specific, partly forced, position of the body at work and the shift work system. Exposure to chemical agents present in exhaust gas may increase the incidence of cancer at some sites in this group of drivers. Multifaceted burdens occurring in this occupation may impair health, leading to temporary or permanent disability to work. Therefore, there is an urgent need to develop specific preventive programs addressed to this occupational group not only because of economic reasons, but mostly to increase public transport safety.
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PMID:[Selected work-related health problems in drivers of public transport vehicles]. 1678 Jan 75

We report a rare case of sarcoidosis-lymphoma syndrome with vertebral bone destruction. A 63-year-old woman was previously diagnosed as sarcoidosis by supraclavicular lymph node biopsy, and came to our hospital complaining of back pain. Both serum angiotensin-converting enzyme and lysozyme level had been continuously elevated. Magnetic resonance imaging revealed lumbar vertebral bone destruction. Histopathologic examination of lumbar vertebral tumor obtained by CT-guided biopsy revealed non-caseating epithelioid granuloma with CD 68 (+), AE1/AE3 (-), and no malignant cells. She was admitted to our hospital again for dyspnea and pancytopenia. We diagnosed active sarcoidosis and administered oral 30mg prednisolone daily. One month later, prednisolone became ineffective. Flow cytometry of tumor cells obtained from the gastric ulcer floor showed CD 5 (+), CD 20 (+), K chain monoclonality and we diagnosed B-cell non Hodgkin's lymphoma. She was treated by eight cycles of CHOP plus rituximab chemotherapy and achieved complete response. FDG uptake of the entire body decreased, whereas MRI revealed residual mass in the vertebrae. Sarcoidosis had been diagnosed for two and half years before lymphoma developed. Bone destruction is very rare and sarcoidosis is rarely the cause. This is quite an unusual case presenting histologically proved epithelioid granuloma and vertebral destruction in sarcoidosis-lymphoma syndrome.
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PMID:[Sarcoidosis-lymphoma syndrome with vertebral bone destruction]. 1999 5

Why do so many patients opt for a surgical solution to lumbosacral (L-S) radicular pain? A rhetoric as well as specific question.Recently a Big Ten coach underwent the scalpel for the third time in two years. "Pain" not masochism was his response when questioned by the press, "Why the knife?"Most physicians and patients equate the severity of L-S radicular pain with the seriousness of the disc derangement.This is not so!Most physicians are aware that radicular pain is inversely proportional to the weakness associated with L-S disc herniation or extrusion. The natural history is a general remission of pain with a little exercise, perhaps some medication, and mostly Mother Nature.A sudden cessation of pain suggests a "dead" root and significant weakness. Unfortunate? Not necessarily.Electrodiagnostic studies can demonstrate a L-S radiculopathy within two weeks of onset and after one week can differentiate neurapraxic (reversible) weakness from permanent weakness.In both instances surgery is not the treatment of choice. In the first instance a conduction block at this inflamed nerve root is the problem and in the second scenario the weakness is generally not reversible with surgery (in fact the operation could be blamed).Nonradicular back pain needs a physiatric evaluation and management program.Patients should be reassured in all situations that most people "get over" acute back pain (including radicular) with minimal residuals if they are patient and educable!After all, rehabilitation is essentially teaching and patient learning. All patients with low back pain need thorough grounding in anatomy and physiology of the low back and biomechanics of lifting, in order to fend off advice of well-meaning friends, relatives, or even other "health" professionals.A recent study announced 10 times more lumbar laminectomies are done in the United States than in Europe. To reduce this number, I suggest all second opinions for this major (e.g., Discectomy) lumbar assault be given by a nonsurgeon who understands back problems (i.e., a physiatrist).Isn't this essentially the same as a gastroenterologist presenting a second opinion for management of a gastric ulcer-medical versus surgical?A physiatrist would provide a second opinion instead of a seconding opinion.
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PMID:Low back pain. 2457 48

We report the case of an 84-year-old male, who presented with septicaemia, abdominal and back pain. The patient had a background of oesophageal carcinoma and had undergone previous oesophagectomy and gastric pull-up operation 10 years ago. A computerised topography scan demonstrated a probable gastro-vertebral communication with a destructive process at the T8/T9 vertebral level. Further evaluation with MRI clearly showed the tract between the two structures and confirmed the diagnosis of spondylodiscitis at the adjacent spinal level. The patient was resuscitated, treated with intravenous antibiotics and kept nil by mouth. A subsequent gastroscopy demonstrated an eroding gastric ulcer at the enteric opening of the tract between the tubal stomach and the spinal column. The diagnosis was discussed with the patient, his family and the surgical multidisciplinary team. Given the extent of disease and his multiple medical co-morbidities, the decision was made for conservative management and symptom control. This is the first case of a gastro-vertebral communication causing spondylodiscitis to be described in the literature.
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PMID:Gastric ulceration causing thoracic spondylodiscitis: a first case of a rare complication post oesophagectomy. 3113 Nov 13