Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors discuss a case of spontaneous esophageal rupture consequent to hematemesis associated with gastric ulcer. This is known as Boerhaave's syndrome. The present case was seen in a male patient of 54 years of age. The diagnosis was suspected on the basis of the clinical history and was confirmed by radiologic studies both with and without contrast medium. The patient was treated surgically through a left anterior thoracotomy. In the immediate postoperative period there was an episode of bloody pleural effusion which was corrected by two thoracocenteses. At the present time the patient leads a normal life with no restrictions. He has not had signs or symptoms of gastric ulcer and two esophageal-gastroduodenal series have only shown the esophageal scar.
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PMID:[Spontaneous rupture of the esophagus after hematemesis from gastric ulcer. Report of a case]. 123 71

A 72-year-old woman who had been given heavy premedication nonetheless developed severe retching at the beginning of a gastroscopy (for suspected gastric ulcer) when the instrument had been advanced only as far as the throat. The investigation was at once terminated, but barium swallow immediately afterwards revealed rupture at the middle third of the oesophagus, with contrast medium flowing into the mediastinum. Despite emergency thoracotomy and suturing of a 4 cm long fresh oesophageal tear in the area of a diverticulum, the patient died from a purulent mediastinitis and confluent pneumonia. The cause of this "spontaneous" rupture of the oesophagus without direct transmission of force (Boerhaave syndrome) in this case was a marked pressure increase in the oesophagus from retching and hyperperistalsis preparatory to gastroscopy. There had definitely not been any instrumental perforation. There was thus no medical negligence.
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PMID:[An unusual case of Boerhave syndrome. Esophageal rupture during preparation for gastroscopy]. 392 25