Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Suppurative pylephlebitis is an unusual disease with an associated high mortality. Most cases are a complication of an intra-abdominal septic focus, but some may occur de novo. In the case we have presented, the diagnosis was made by modern imaging techniques that showed thrombus predominantly within the upper portal venous system. We hypothesize that the portal system was seeded through a gastric ulcer. The patient recovered completely with prolonged antibiotic therapy.
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PMID:Suppurative pylephlebitis. 194 34

We report a case of patient with Clostridium perfringens septicemia and thrombophlebitis of the portal vein (pylephlebitis), probably secondary to an initially unrecognized gastric ulcer. The extension of the thrombosis from the superior mesenteric vein to the main portal vein on a repeat CT scan and subsequent partial resolution of the thrombus with antibiotic therapy alone, suggested that Clostridium perfringens bacteremia may have enhanced the formation of thrombus. The coexistence of Clostridium perfringens septicemia and pylephlebitis should prompt a search for intra-abdominal processes as the portal of entry of infection.
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PMID:Clostridium perfringens septicemia with thrombophlebitis of the portal vein. 1279 55