Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We studied the involvement of serotoninergic system into postprandial motility of the stomach and small intestine and into the development of experimental myocarditis and stomach ulcer. Gradual increase in activity of this system was observed under pathological conditions.
 ...
PMID:Serotoninergic nervous system of the heart and abdominal organs during functional load and pathology. 1545 95

The authors researched into the mechanisms through which the sympathetic nerve intensifies the vagal stimulation of the gastroduodenal, urinary bladder, uterine and deferent duct motility and the vagal inhibition of heart functioning. It was shown that these phenomena are mediated by preganglionic serotoninergic fibers conducting excitement to intramural serotoninergic neurons. The study found a growing cranio-caudal gradient of the serotoninergic innervation of visceral organs. The mechanism of gastroduodenal motility activation includes intramural serotoninergic neurons, which conduct excitement to 5-HT1,2 -serotonin receptors of the effector tissues. A model of myocarditis and experimental gastric ulcer demonstrated the cardio- and gastroduodenoprotectory effects of the serotonin blockers.
 ...
PMID:[The serotoninergic division of the vegetative nervous system under normal and pathological conditions]. 1577 60

We report on two cases involving hepatic portal venous gas (HPVG) imaging by computed tomography (CT) scans performed shortly after death. One case involved a 9-month-old infant who died of heat stroke, while the other was a 28-year-old man who died of myocarditis. Although both of these two cases were remarkable distension of the gastrointestinal tract with gas, the autopsies were unable to uncover any clinical cause for HPVG, such as necrotic bowel, ulcerative colitis, intra-abdominal abscess, bowel obstruction, or gastric ulcer. The cause of HPVG in our case is not due to organic disease, but due to gastro-intestinal distention due to emergency management using bag-valve-masking or esophageal tracheal combitube, thereby differing from the mechanisms underlying so-called clinical HPVG.
 ...
PMID:Hepatic portal venous gas on postmortem CT scan. 1605 57