Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 33 patients (duodenal ulcer 11, gastric ulcer 10, nonulcerous bulbar lesions 7, anastomotic ulcer 4, antral erosions 1), approximately 4 ml HCL 0,1 N were instilled under endoscopic view directly onto the lesion, with the purpose of eliciting patients-specific pain. Five (5) patients were test-positive; their pain was reproduced (duodenal ulcer 1, gastric ulcer 2, other bulbar lesions 2), the rest was negative. Twenty-three of the 33 patients were studied during a period of spontaneous pain, 4 exhibiting a positive test; 9 were asymptomatic, and 2 of these had a positive test. The role of acid in ulcer pain remains unclear. The pertinent literature is discussed.
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PMID:[The role of acid in ulcer pain (author's transl)]. 725 80