Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038358 (gastric ulcer)
 5,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 50-year-old man experienced epigastric pain and gastrofiberscopy (GF) disclosed A2 to H1 stage multiple ulcerative lesions in the stomach. Inclusion bodies were found in the gastric mucosal cells of the biopsy specimen and the cells were positive for monoclonal antibody against cytomegalovirus. Serum HTLV-I antibody was positive and no atypical lymphocytes were seen in the peripheral blood. Gancyclovir and lansoprazole were given. A follow-up GF showed good ulcer healing with immunohistological improvement. The patient died from acute hepatic failure of undetermined cause eleven months after diagnosis. This is the first case report where a cytomegaloviral-induced gastric ulcer disclosed HTLV-I carrier state.
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PMID:HTLV-I carrier status disclosed at diagnosis of cytomegalovirus gastric ulcer. 1253 56