Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038220 (status epilepticus)
7,272 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of complex partial status epilepticus presenting as recurring episodes of altered mental status and subtle automatisms after bone marrow transplantation (BMT) for non-Hodgkin's lymphoma. Early recognition of complex partial status epilepticus as a cause of altered mental status is important as prompt treatment with antiepileptic drugs improves neurologic outcome.
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PMID:Complex partial status epilepticus after bone marrow transplantation for non-Hodgkin's lymphoma. 908 46

A 66-year-old woman presented with new onset generalised tonic-clonic seizures following her first dose of chemotherapy comprising Rituximab, Cyclophosphamide, Hydroxydaunorubicin, Oncovin and Prednisolone (R-CHOP) 10 days earlier for non-Hodgkin's lymphoma. On admission, computed tomography (CT) scan of the cranium showed no abnormality. The CT was repeated within 48 hours as the patient developed status epilepticus and papilledema; the repeat scan showed characteristics of posterior reversible encephalopathy syndrome (PRES). Association of rituximab with this condition was suspected as there was no recurrence of PRES after receiving two more cycles of CHOP without rituximab. Contrary to previously published case reports, this patient had a delayed clinical presentation.
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PMID:Rituximab as a possible cause of posterior reversible encephalopathy syndrome. 2339 43