Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038220 (status epilepticus)
 7,272 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Complex partial status epilepticus (CPSE) has rarely been reported in children. We experienced a 5-year-old girl having had an abrupt onset of complex partial seizure with a fluctuating state of consciousness and aphasia. Electroencephalogram revealed repetitive epileptiform discharges originating from bilateral temporal and parieto-occipital regions over the background of diffuse continuous slow activity. Computerized tomography of the brain showed mild atrophy without focal lesions. All the other studies including bacteriology, virology, toxicology and metabolic screening were unremarkable. Intravenous administration of diazepam was ineffective for recovery of consciousness level and cease of seizure activity. A lasting control of the status was not achieved until intravenous phenytoin and oral carbamazepine were added for one more weeks. Paroxysmal attacks of periodic apnea with subsequent hyperpneic movements occurred the fourth month after the onset of illness. She regained language on rehabilitation program. Unfortunately, the patient had recurrence four months later despite medication. Finally, she died of aspiration pneumonia and status epilepticus eleven months after the onset of the disease. Compared with the other previously documented cases of prolonged complex partial status epilepticus, this case is notable for its unusual, complicated and severe symptomatology and long duration (three more months) with poor prognosis.
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PMID:Complex partial status epilepticus: report of one case. 263 6

A 64-year-old man developed lethargy and aphasia immediately following cerebral arteriography with iothalamate meglumine. An electroencephalogram showed continuous epileptiform activity. The patient was treated with intravenous phenytoin with complete resolution of clinical symptoms and electroencephalographic epileptiform abnormalities. The diagnosis of nonconvulsive status epilepticus should be considered in cases of altered consciousness following cerebral arteriography.
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PMID:Nonconvulsive status epilepticus following cerebral angiography. 291 70

Benign partial epilepsies of childhood (BPEC) are one of the most frequent types of epilepsy in school-age children. Status epilepticus (SE) of these conditions have not yet been reported. Two children with clinical and EEG features consistent with the diagnosis of BPEC-SE are presented. In neither case did SE respond to current antiepileptic medications and stopped only after administration of steroids. At follow-up 1 and 2 years post SE, neurologic and intellectual development have been normal. Differential diagnoses included an atypical benign partial epilepsy, epilepsy with electrical status epilepticus during slow sleep, acquired epileptic aphasia, Lennox-Gastaut syndrome and epilepsia partialis continua.
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PMID:Status epilepticus of benign partial epilepsies in children: report of two cases. 311 24

We studied a case of focal status epilepticus with aphasia as the sole manifestation, lasting 21 days. A 77-year-old woman developed aphasic seizures followed by aphasic status epilepticus 10 months after a left temporo-occipital hemorrhage. The diagnosis was made only after EEG, and seizures were stopped by anticonvulsant medication. Aphasic status epilepticus may be only a reflection of cerebral irritability, suggesting the possibility of a functional etiology for prolonged language disorders also in adults.
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PMID:Aphasic status epilepticus. 322 19

Electrical status epilepticus during slow sleep (ESES) is characterized by an EEG picture that justifies its name. It can be accompanied by epileptic seizures, speech and behavior disturbances and in rare cases by an acquired sensory aphasia. We describe the case of a six-year-old girl, whose EEG presented the typical ESES picture, and who in the span of one year developed a complete sensory aphasia, followed by motor aphasia. After 6 months of treatment with clobazam recovery of speech was nearly complete, but after 8 months clobazam lost its effectiveness and the girl presented a speech regression. Treatment with nitrazepam led to a complete recovery of speech for a second time, while at the same time ESES in the EEG again disappeared. This case, in addition to others described in the literature, suggests the possibility of a direct correlation between electrical abnormalities of the brain and cognitive and speech disturbances.
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PMID:Electrical status epilepticus during slow sleep: one case with sensory aphasia. 339 7

Three patients are described who developed cerebral complications and an EEG abnormality for several days after metrizamide myelography. Clinically, the patients showed a fluctuating confusional state with dysphasia and retrograde amnesia, while their EEGs were dominated by runs of slow wave activity interspersed with frequent spikes. The runs appeared either continuously or in paroxysmal bursts. The clinical symptoms and the EEG are compatible with complex partial status epilepticus and are similar to the symptomatology of ten patients described in the literature. This rare clinical entity should be distinguished from a more common complication of metrizamide--non-specific slow wave abnormality of variable degree in the EEG with or without clinical signs. Clinical manifestations may include transient aphasia and weakness of the limbs with pyramidal signs.
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PMID:Metrizamide and the EEG: three case reports and a review. 407 99

We studied the clinical features, ictal manifestations, and EEG phenomena of eight patients with partial complex status epilepticus documented by video/EEG. Age at the time of status was 18 months to 56 years. All patients had had previous seizures, and seven had previous episodes of status. In three patients, status consisted of confusion associated with continuous focal electrographic ictal activity. Five patients had confusion, aphasia, motor phenomena, or automatisms associated with recurrent partial electrographic seizures. Data from 17 previously reported cases were comparable with our 8 patients.
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PMID:Partial complex status epilepticus. 668 27

Four cases of acquired aphasia in epileptic children, associated with sub-continuous bitemporal paroxysmal activities (PA) during sleep, are described. Clinical improvement always followed the decrease or the unilateralization of PA. Persistence or aggravation of aphasia was observed when PA again became bitemporal and sub-continuous. Electroencephalographic characteristics of PA during sleep stages are described. Relationships of these cases with the 'sub-clinical electrical status epilepticus induced by sleep' and the physiopathology of aphasia are discussed.
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PMID:[Acquired aphasia in epileptic children--four cases with electrical infraclinic status epilepticus during sleep (author's transl)]. 680 3

We report 3 cases of opercular myoclonic status epilepticus (OMASE), characterized by fluctuating cortical dysarthria without true aphasia associated with epileptic myoclonus involving bilaterally the glossopharyngeal musculature. In this syndrome, the inferior rolandic area of either one or the other hemisphere is involved by an epileptogenic lesion of various etiology. Ictally, clonic expression was consistent with epilepsia partialis continua (EPC) and bilaterally and symmetrically involved palatal muscles (cases 1-3), tongue (cases 2 and 3), lips and chin (case 3), and inferior jaw (case 1) due to bilateral projections of the inferior corticonuclear pathways. Postictally, the main clinical sign was pseudobulbar palsy, consistent with Todd's palsy. In our cases, OMASE was either of vascular (cases 1 and 2) or tumoral origin (case 3). In adulthood, early recognition of OMASE, although nonspecific, may be important for early management of carotid occlusive disease because it usually indicates an acute opercular infarction.
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PMID:Opercular myoclonic-anarthric status epilepticus. 761 13

We present a patient with aphasia of several days' duration that was secondary to spontaneous partial status epilepticus arising from the left basal temporal region. Evidence from MRI, EEG, and PET confirmed the origin of the seizures in the basal temporal area. Both the seizure discharges and the aphasia resolved after antiepileptic therapy. This case, to our knowledge, is the first documented example of epileptic aphasia secondary to spontaneous partial status epilepticus originating from the basal temporal area.
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PMID:Aphasia secondary to partial status epilepticus of the basal temporal language area. 764 64


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