Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038220 (
status epilepticus
)
7,272
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Aphasia
was the sole manifestation of focal
status epilepticus
in a man with an old left frontal contusion. The diagnosis was made by electroencephalogram (EEG), and the attack was terminated by anticonvulsant medication.
...
PMID:Aphasia: the sole manifestation of focal status epilepticus. 10 12
Two patients, aged 23 and 74 years, manifested prolonged episodes of mildly impaired consciousness in conjunction with rhythmical spike waves or spikes (mostly 3/s). This paroxysmal EEG activity was consistently accentuated unilaterally over the superior frontal regions. The first patient showed ictal
aphasia
and occasional right hemiparesis during these episodes, and partial left frontal lobectomy resulted in temporary freedom from seizures. The classification of these ictal episodes is difficult. They apparently fall into the category of absence status (petit mal status), but the focal neurological signs do not fit the presently valid definitions of absence status, nor does the lack of symmetrical bilateral-synchronous paroxysmal discharges. Perhaps a special category of
status epilepticus
should be established.
...
PMID:Absence status (petit mal status) with focal characteristics. 11 Feb 95
Seven cases of SLE with concomitant neurological syndromes are reported. In 2 cases brain stroke with right-sided hemiplegia and
aphasia
developed, in the remaining cases brain-stem stroke with subarachnoid haemorrhage, progressive hemiparesis and signs of intracranial hypertension, chorea,
status epilepticus
in terminal uraemia were observed. In one case myasthenia coexisted. Severe neurological syndromes were preceded by signs of involvement of other organs and in most cases by low-grade signs of central nervous system involvement. Treatment with corticosteroids and immunosuppressants resulted in significant improvement without complete remission. A retrospective survey of clinical material showed that modern therapeutic methods have improved the prognosis in systemic lupus erythematosus independently of central nervous system involvement.
...
PMID:[Neurological syndromes in the course of systemic lupus erythematosus]. 52 35
The paper is centered in the comparative study of three groups of long-term epileptic patients in which therapeutic control is difficult to achieve, by means of several neuropsychological tests evaluating levels of intelligence, memory, language and praxis. Paget's tests of conservation of physical quantities revealed no significant differences in results obtained from the exploration of operative levels between epileptics with right temporal, left temporal or centrencephalic electroencephalographic foci. There is no parallel decrease of operative level when present, and deficit of mnesic functions, which is constantly observed in the three groups and usually evidenced in short-term memory. The graphic representation of projective space (Cube, house), is parallel to operative weakening. No significant relationship between lateralization of focus and graphic performance is observed. Language exploration by means of Benton and Spreen's battery of tests shows distinctly similar results in the three groups of patients. The location of the epileptic focus shows no relevance with respect to language disturbances. The most outstanding pathologic phenomenon is a certain degree of anomia observed in the naming of objects. Its significance is discussed (Slight degree of amnesic
aphasia
, deficit of evocative memory, or a lexical level in accordance with the operative deficit). The deficit of the repetition of sentences test and in others including a time element should not be ascribed to a specific language deficit. True aphasia was present in only three patients of the left temporal group after prolonged
status epilepticus
.
...
PMID:[Comparative study of the cognitive functions and symbolic order in temporal and centerencephalic epilepsy of long development of difficult therapeutic control]. 124 6
We report a girl 3 years and 6 months old with onset of
aphasia
at age 3 years and 3 months. There was no evidence of brain damage and there were no seizures. The neuropsychological evaluation showed that the girl tended to be right-handed, that
aphasia
was global and that other higher cortical functions seemed to be preserved. Isolated spikes and spikes-and-wave were recorded during wake over the right temporal region with rare independent contralateral abnormalities. During polysomnography (PSG), the physiological patterns of sleep were preserved and right temporal epileptiform discharges were significantly increased in all sleep stages. Maximal activation was obtained at sleep onset and during rapid eye movement (REM) sleep periods, when focal abnormalities became continuous and spread contralaterally. Repeat PSGs showed that the activation profile retained this particular trait, although subclinical discharges tended to increase during slow wave sleep (SWS). This pattern of subclinical temporal
status epilepticus
during REM sleep differs from the characteristic activation profile found in the syndrome of continuous spikes-and-waves during SWS. However, this profile was transient and all epileptiform changes disappeared during clinical recovery at 18 months of follow-up.
...
PMID:Continuous focal spikes during REM sleep in a case of acquired aphasia (Landau-Kleffner syndrome). 128 Aug 54
Aphasia
due to simple partial
status epilepticus
is rare, particularly in the absence of a seizure history. No previous report describes acute
aphasia
as the sole clinical manifestation of EEG-monitored
status epilepticus
, with prompt resolution with treatment. We report a 45-year-old man with a left temporal glioblastoma who acutely developed a global aphasia, during which an EEG revealed continual repetitive sharp waves emanating from the left hemisphere. After injection of i.v. diazepam, the EEG seizure activity ceased, and the patient's language output returned to preseizure levels.
...
PMID:Aphasia as the sole manifestation of simple partial status epilepticus. 137 Aug 1
We present six patients with acquired
aphasia
with convulsive disorder (Landau-Kleffner syndrome) and distill the main clinical features from a review of the recent literature. Our series showed that the clinical picture can vary at onset, as well as during the course of the illness, and that the long-term outcome of the
aphasia
is quite unpredictable, despite the fact that epilepsy and electroencephalographic abnormalities usually regress or disappear with the years. We also call attention to the electroencephalographic phenomenon of electrical
status epilepticus
during slow sleep, and we suggest that the course of the
aphasia
may well be linked to the appearance and disappearance of electrical
status epilepticus
during slow sleep. Therefore, we recommend a sleep electroencephalogram in all children with Landau-Kleffner syndrome. Finally, our findings did not demonstrate the beneficial effect of treatment with anticonvulsants on the
aphasia
, but recent studies have shown that treatment with corticosteroids, whether combined with anticonvulsants, is effective.
...
PMID:The Landau-Kleffner syndrome or 'acquired aphasia with convulsive disorder'. Long-term follow-up of six children and a review of the recent literature. 769 38
The correlations between sleep and prolonged epileptic activity are discussed on the basis of the status classification of Gastaut (1983). Little information is available on the interrelation of sleep and the status of tonic-clonic seizures (grand mal status). Most important is the therapeutical management of these cases. Tonic seizures have been reported to occur in large numbers during NREM sleep in patients with Lennox-Gastaut syndrome. A status-like increase is possible. Tonic seizures occur almost exclusively during sleep. Myoclonic
status epilepticus
arising (a) in the course of primary generalized epilepsy and (b) in the course of encephalopathies, are usually markedly attenuated during sleep. In absence status (petit mal status) synchronized sleep generally fragments the continuous discharge which is replaced by isolated bursts of polyspikes, or polyspike and wave complexes. The absence status can recur upon awaking during the night or in the morning. The abnormal EEG activity of a petit mal status can, however, occasionally persist during the whole night. Improvement as well as activation during sleep have been observed in elementary (= simple) partial
status epilepticus
; improvement seems to be more frequent. Epilepsia partialis continua may persist or decrease during sleep. An increase as well as decrease of motor phenomena has been observed during the REM stages. 'Epileptic
aphasia
' of childhood is associated with subclinical bioelectric
status epilepticus
during sleep. The electrical
status epilepticus
must be delineated as a separate group. The term encephalopathy related to electrical
status epilepticus
during slow sleep (ESES) has been proposed on the basis of associated psychic syndromes. This form of
status epilepticus
disappears during the waking state and during REM sleep. Cases with hypsarrhythmia without clinical signs may also be classified under the group of electrical or bioelectrical status. In some cases, a continuous hypsarrhythmia is observed only during sleep. In this context, one must also mention those patients who demonstrate continuous activation of spikes, or spike and wave potentials (without clinical seizures) during eye closure.
...
PMID:Sleep and prolonged epileptic activity (status epilepticus). 176 86
Aphasia
as the sole manifestation of focal
status epilepticus
in adult is rarely described. Such a case is reported here. Two separate episodes were studied: 1) prolonged mixed
aphasia
with continuous epileptic patterns; 2) Epileptic
aphasia
organized in shortly spaced temporal seizures marked by total suspension of speech, paraphasic utterances characterizing the interictal period. The clinical and EEG criteria and nosographic situation of this syndrome are reviewed. We conclude that epileptic
aphasia
exists if a fixed and lasting epileptic condition is created, even if a post-ictal phenomenon accounts for the symptomatology.
...
PMID:[Status epilepticus with aphasic manifestation]. 206 73
Prolonged isolated sialorrhea of epileptic origin was described by Penfield and Jasper (1954) in a patient with a lesional epilepsy. A child with prolonged but intermittent drooling, lingual dyspraxia, and other clinical and electroencephalographic (EEG) features compatible with benign childhood epilepsy with centrotemporal spikes (BCECS) is described. The fluctuant course of the symptomatology and correlation with the intensity of the paroxysmal discharges on EEG are consistent with an epileptic dysfunction located in the lower rolandic fissure. No lesion was demonstrated by magnetic resonance imaging (MRI). Our case bears analogies with the recently reported
status epilepticus
of BCECS and the "acquired
aphasia
-epilepsy syndrome."
...
PMID:Prolonged intermittent drooling and oromotor dyspraxia in benign childhood epilepsy with centrotemporal spikes. 250 2
1
2
3
4
5
6
7
8
9
10
Next >>