Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038187 (
starvation
)
24,951
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
2103
Sep
1527
insulin
1290
ATP
767
LC3
443
endoplasmic reticulum
432
mTOR
419
Pseudomonas
377
Dictyostelium
355
AMP
299
ubiquitin
299
Gen
282
tRNA
279
glucagon
273
gut
266
p53
255
proteasome
252
leptin
250
phosphatase
238
ATPase
233
polypeptide
218
cytokine
193
caspase-3
190
catalase
178
Bcl-2
178
p62
174
AMP-activated protein kinase
173
threonine
172
fused
168
PCC
162
acid phosphatase
151
GTP
151
growth hormone
151
Chlamydomonas
140
transcriptional activator
140
AMPK
139
PI3K
138
ULK1
137
membrane protein
137
histone
134
NAD
131
ADP
130
alkaline phosphatase
130
MAPK
130
CO2
130
AKT
127
Beclin-1
125
glutamine synthetase
123
superoxide dismutase
122
phosphatidylinositol 3-kinase
122
TOR
119
Bot
118
reductase
117
membrane-bound
115
NMR
107
NADPH
107
cyclin
107
transcriptional regulator
103
GCN2
103
GSH
103
PDB
101
NADH
101
phosphoenolpyruvate carboxykinase
100
ATG5
98
ERK
92
thyroid hormone
91
ROS
91
Leptin
90
GTPase
90
microsomal
89
muscle protein
85
p21
84
ghrelin
84
p38
84
albumin
82
ERK1
82
ATG8
81
Pol
79
SDS
79
pyruvate kinase
79
unknown function
78
D. melanogaster
77
lipase
77
ribosomal protein
76
UTR
75
pyruvate dehydrogenase
75
glycoprotein
75
neuropeptide Y
75
collagen
74
TORC1
73
phosphodiesterase
71
lipopolysaccharide
71
hexokinase
68
microtubule-associated protein
68
transferrin
67
LC3B
67
casein
66
ferritin
66
cytochrome c
65
ATG7
65
p27
65
adenylate cyclase
64
JNK
63
serum albumin
62
cytochrome
62
PKA
61
glutamate dehydrogenase
61
SOD
61
phosphorylating
60
protein phosphatase
60
insulin-like growth factor
60
MAP kinase
60
tyrosine kinase
60
amylase
58
tumor necrosis factor
58
IGF-1
57
RNase
56
housekeeping
56
cage
55
TCA
55
cyclin D1
54
ACS
53
ATF4
53
hemoglobin
53
beta-endorphin
53
GDP
53
NADP
53
heat shock protein
53
DNase I
53
epidermal growth factor
52
glycogen synthase
51
cryptic
51
IGF-I
51
glucose transporter
51
c-myc
51
A-I
51
prolactin
50
pyruvate dehydrogenase complex
50
glucose-6-phosphate dehydrogenase
50
serine/threonine kinase
50
RNA polymerase II
49
insulin receptor
49
MYB
49
peroxidase
48
epididymal
48
cyclin-dependent kinase
47
PHR1
47
ACTH
47
ornithine decarboxylase
47
C18
47
lipoprotein lipase
47
TNF
47
ATG12
47
FRAP
47
phosphofructokinase
46
histone deacetylase
45
interacting protein
45
A. nidulans
45
cAMP-dependent protein kinase
45
Vps34
45
more...
Disease
cancer
1474
tumor
1005
diabetes
533
obesity
439
cold
421
malnutrition
372
anorexia nervosa
350
Mycobacterium
248
tuberculosis
210
breast cancer
187
pheochromocytoma
184
hepatocellular carcinoma
183
tumor growth
174
hypoglycemia
165
PCC
163
depression
160
tumorigenesis
159
ischemia
144
dehydration
131
sepsis
130
carcinoma
127
tumor progression
119
infectious diseases
118
sepsis
113
ketosis
108
GSH
103
worms
93
leukemia
92
type 2 diabetes
87
MCF
86
Alzheimer's disease
84
eating disorder
80
SDS
80
hyperglycemia
77
hyperphagia
75
neuroblastoma
75
carcinogenesis
75
glioma
72
cholera
72
melanoma
71
wasting
71
heart failure
69
fatty liver
68
adenocarcinoma
67
virus infection
67
colon cancer
66
prostate cancer
63
pancreatic cancer
57
lung cancer
55
bulimia nervosa
55
Infection
54
iron deficiency
54
metabolic syndrome
52
atherosclerosis
52
HIV
52
pneumonia
49
colorectal cancer
48
muscular atrophy
48
Parkinson's disease
48
mental illness
45
binge eating
44
SEM
44
diabetic ketoacidosis
44
AIDS
44
malaria
44
hypertension
42
Cryptococcus neoformans
41
cirrhosis
40
lymphoma
40
retinoblastoma
39
multiple myeloma
39
hyperinsulinemia
38
metastases
37
cardiovascular disease
37
hypothyroidism
37
hyperthyroidism
37
Klebsiella
37
Chagas
36
anemia
36
abortion
36
chlorosis
35
stroke
35
Blocking
35
FBS
34
suicide
33
immunodeficiency
33
plaque
32
coma
32
glioblastoma
32
non-small cell lung cancer
32
ovarian cancer
32
alcoholism
32
aggression
30
cystic fibrosis
30
squamous cell carcinoma
30
pertussis
30
glucose intolerance
30
Yersinia
29
osteosarcoma
29
Legionella
29
epilepsy
28
amenorrhea
27
myocardial infarction
27
West
27
amyotrophic lateral sclerosis
27
Bordetella
26
Chlamydia
25
uremia
25
osteoporosis
25
sarcoma
25
bacterial infection
24
addiction
24
aggressiveness
24
tuberous sclerosis
24
Huntington's disease
24
liver disease
23
myopathy
23
ATM
22
malabsorption
22
gastric cancer
22
type 1 diabetes
22
myocardial ischemia
21
rheumatoid arthritis
21
infertility
21
liver cancer
20
Epstein
20
Haemophilus
20
renal cell carcinoma
20
protein deficiency
20
TEM
20
dementia
20
TEM
20
fits
20
epithelial ovarian cancer
20
acute myeloid leukemia
19
ash
19
violence
19
Crohn's disease
19
Adhesion
18
Still
18
chronic renal failure
18
Brown
18
confusion
18
abdominal aortic aneurysm
17
dyslipidemia
17
hepatitis B
17
hyperlipidemia
17
chronic disease
17
renal failure
17
congestive heart failure
17
pancreatitis
17
AAA
16
ARF
16
aspergillosis
16
Mycoplasma
16
gastroenteritis
16
uterus
16
acute promyelocytic leukemia
16
APC
16
herpes simplex
16
more...
Symptom
starvation
24951
anorexia
176
hunger
141
cachexia
113
exhaustion
95
anesthesia
69
hypothermia
67
vomiting
65
fatigue
53
diarrhea
48
collapse
43
acidity
41
seizures
39
overweight
39
pain
34
emaciation
34
tremor
24
weakness
24
ketonuria
22
ataxia
22
chills
21
acute stress
19
nausea
18
abdominal pain
18
hyperoxia
15
agitation
15
thinning
14
inanition
12
hyperemesis gravidarum
11
lethargy
11
nausea and vomiting
10
analgesia
10
constipation
9
Ill
8
discomfort
7
discomfort
7
apathy
5
hepatomegaly
5
asthenia
5
stigma
5
twitching
5
bloating
5
decreased appetite
4
hyperemesis
4
dyspnea
4
dystonia
4
polyuria
4
autodigestion
4
spasticity
4
functional recovery
4
flushing
4
polydipsia
4
Anoxia
4
hypercapnia
4
Catch
4
hypotonia
4
cyanosis
3
regurgitation
3
sleepiness
3
HSA
3
bitter taste
3
insomnia
3
respiratory distress
3
incoordination
3
livedo
3
alexithymia
3
cerebellar ataxia
3
hypoproteinemia
3
exertional dyspnea
2
aphagia
2
physical appearance
2
angina
2
Depressive symptoms
2
loss of equilibrium
2
memory loss
2
Mills
2
headache
2
Tissue sensitivity
2
chest pain
2
myalgia
2
hepatosplenomegaly
2
CSR
2
retching
2
Sedation
1
paraparesis
1
Stinging
1
shortness of breath
1
thirsty
1
colic
1
epigastric pain
1
Spastic
1
staggering gait
1
Stomach fullness
1
High weight
1
ataxic gait
1
paresis
1
syncope
1
Decreased activity
1
cough
1
paresthesia
1
anosmia
1
Excitability
1
loss of balance
1
dizziness
1
corpulence
1
dental pain
1
despair
1
tachypnea
1
hopelessness
1
Fluctuation
1
hypersomnia
1
enuresis
1
labored breathing
1
belching
1
facial pain
1
abnormal gait
1
mental fatigue
1
stomach distension
1
carpopedal spasm
1
erythema
1
Wind
1
Hudson
1
Chronic vomiting
1
vertigo
1
Amputated
1
Crushing
1
general problem
1
acute abdomen
1
wheezing
1
feeling tired
1
Scratch
1
Welt
1
catatonia
1
hyperesthesia
1
microbial colonization
1
ENT
1
Opisthotonus
1
adipsia
1
splenomegaly
1
Appetite suppression
1
bone pain
1
Drug
lysine
217
NADH
102
ROS
91
lactose
63
Leaf
55
DNase I
53
ABC
39
citric acid
37
caffeine
35
Glucagon
35
ascorbate
32
Gel
29
Dermatol
27
balanced salt solution
25
Glycerol
22
Parkin
21
MAP
21
Parkin
21
Alanine
21
ampicillin
21
Glutathione
20
IFN-gamma
20
Ethanol
20
Fructose
19
Asn
18
IL-2
18
RFP
17
Cardiovasc
16
vitamin E
15
Growth hormone
13
Growth hormone
13
Nephron
12
EPA
12
beta-Galactosidase
12
CaCl2
11
FAD
11
CaCl2
11
CaCl2
11
CDP
11
CSF
11
PCB
10
NH3
10
Albumin
9
MgSO4
9
Heme
9
L-tyrosine
8
DMAP
8
Portal
8
Clofibrate
8
Kenyan
7
Capsicum
7
Bifidobacterium
7
Carotenoid
7
NAG
7
Angiotensin II
7
Diurnal
7
niacin
7
Monit
6
Indomethacin
6
AraC
6
ACT
6
MRC
6
Spectrum
6
CED
6
G418
5
PTH
5
FeCl3
5
Cellulase
5
nitroglycerin
5
THF
5
Taxol
5
Mutagen
5
DHT
5
EE2
5
pyridoxal phosphate
5
CTC
5
Vitamin A
4
Galactose
4
Lactase
4
3-Methyladenine
4
Ringer's solution
4
Adenosine triphosphate
4
Pronase
4
DHT
4
CTC
4
Histamine
4
Sorafenib
4
Ergosterol
4
Alliance
4
Adriamycin
4
GEO
3
p75
3
Vitamin B12
3
Immucillin-G
3
ALA
3
K-252a
3
Forskolin
3
Ouabain
3
AGG
3
Lactose
3
CoCl2
3
Gelatin
3
MOF
3
Nephron
3
Asparaginase
3
FLP
3
AMC
3
Spectrum
3
CoCl2
3
PPA
3
IPM
2
Cimetidine
2
Vitamin E
2
CTX
2
Etoposide
2
ETS
2
Herceptin
2
Adenosine deaminase
2
GNA
2
Serum albumin
2
Bortezomib
2
GHRP
2
Salicylate
2
HCH
2
IFN-beta
2
Prednisolone
2
Lovastatin
2
Amiloride
2
AIC
2
Camp
2
Coral
2
Activin
2
Mazindol
2
EML
2
Tacrolimus
2
Retinoic acid
2
KGF
2
L-Asparaginase
2
Cobalamin
2
Histidinol
2
PE2
2
Saha
2
Azilect
2
TMS
2
Phentolamine
2
Desferal
2
Captopril
2
ADR
2
ROC
2
Glycyrrhiza
2
-deoxyadenosine
2
Ranitidine
2
Dihydro
2
Arsenic trioxide
2
BH4
2
CCL
2
Tallow
2
Cimetidine
2
CPR
2
Imatinib
2
more...
Enzyme
protein kinase
546
mitogen-activated protein kinase
395
RNA polymerase
290
AMP-activated protein kinase
285
proteasome
257
ATPase
253
catalase
190
AMPK
184
ERK
180
acid phosphatase
155
caspase-3
150
superoxide dismutase
147
AMPK
139
alkaline phosphatase
134
glutamine synthetase
125
beta-galactosidase
124
phosphatidylinositol 3-kinase
124
phosphoenolpyruvate carboxykinase
122
pyruvate dehydrogenase
119
TOR
119
phosphoenolpyruvate carboxykinase
116
phosphoenolpyruvate carboxykinase
114
calcineurin
106
RNase
102
RNase
101
luciferase
98
protein kinase C
89
lipase
86
cdc2
81
focal adhesion kinase
81
pyruvate kinase
80
pyruvate dehydrogenase
74
phosphodiesterase
74
pyruvate dehydrogenase
74
glucose-6-phosphate dehydrogenase
71
hexokinase
70
PDK1
70
adenylate cyclase
65
glucose oxidase
63
nitrate reductase
63
glutathione S-transferase
62
MEK
62
glutamate dehydrogenase
62
phosphofructokinase
62
glutamate dehydrogenase
61
glutamate dehydrogenase
61
phosphorylase
60
nitrate reductase
60
nitrate reductase
60
nitrate reductase
60
trypsin
60
ACS
59
nitrate reductase
59
nitrate reductase
59
peroxidase
55
alanine aminotransferase
54
CPT
53
reverse transcriptase
52
glyceraldehyde-3-phosphate dehydrogenase
50
lipoprotein lipase
49
ornithine decarboxylase
49
nitrogenase
49
glyceraldehyde-3-phosphate dehydrogenase
47
lactate dehydrogenase
46
invertase
46
lysozyme
44
glucokinase
43
DNA polymerase
42
ribonuclease
41
histidine kinase
41
ribonuclease
41
aspartate aminotransferase
40
beta-glucuronidase
40
arginase
39
glucose-6-phosphatase
38
glutathione peroxidase
37
PARP
37
acetyl-CoA carboxylase
37
phosphoinositide 3-kinase
37
cathepsin D
37
glyceraldehyde-3-phosphate dehydrogenase
37
glutaminase
36
complex I
36
alpha-amylase
36
glyceraldehyde-3-phosphate dehydrogenase
35
glyceraldehyde-3-phosphate dehydrogenase
35
phospholipase C
33
succinate dehydrogenase
32
ATP synthase
31
malate dehydrogenase
30
caspase-9
30
sucrase
27
glutamate synthase
27
chloramphenicol acetyltransferase
27
asparagine synthetase
27
cathepsin B
26
glutamate synthase
26
glutamate synthase
26
asparaginase
26
leucine aminopeptidase
25
glutathione reductase
25
hormone-sensitive lipase
25
citrate synthase
24
ribonucleotide reductase
24
adenosine deaminase
24
indoleamine 2,3-dioxygenase
24
phosphoenolpyruvate carboxylase
24
aldolase
24
gamma-glutamyl transpeptidase
24
isocitrate lyase
23
isocitrate dehydrogenase
23
endonuclease
23
chitinase
23
ClpP
22
ribonucleotide reductase
22
aminopeptidase I
22
demethylase
22
peroxiredoxin
22
aconitase
22
topoisomerase
22
6-phosphogluconate dehydrogenase
22
protein phosphatase 2A
22
6-phosphogluconate dehydrogenase
22
APC
22
renin
21
creatine kinase
21
nitrite reductase
21
nitrite reductase
21
P-glycoprotein
21
ceruloplasmin
21
nitrite reductase
21
isocitrate dehydrogenase
21
aspartate transcarbamylase
21
pyruvate carboxylase
20
ACE
20
NADPH oxidase
20
DNase
20
acyl-CoA synthetase
20
beta-glucosidase
20
beta-glucosidase
20
HMG-CoA synthase
19
urease
19
deaminase
19
ATP sulfurylase
19
alpha-glucosidase
19
collagenase
19
thymidine kinase
19
NADPH oxidase
19
branched-chain alpha-keto acid dehydrogenase
19
histone acetyltransferase
18
cellulase
18
arginine deiminase
18
adenosine deaminase
18
lactase
18
trehalase
18
ornithine transcarbamylase
18
MAT
17
topoisomerase
17
urease
17
elastase
17
more...
Compound
glucose
3301
nitrogen
2434
DNA
2118
phosphate
1869
Dec
1741
oxygen
1129
water
977
iron
895
ATP
769
phosphorus
500
Clin
495
calcium
441
sodium
424
glutamine
419
arginine
384
methionine
376
leucine
372
cAMP
354
serine
343
alanine
333
glycerol
330
ammonium
323
acetate
318
nitrate
308
His
308
galactose
305
AMP
304
ethanol
300
NH2
293
cysteine
288
hydrogen
274
glutamate
269
salt
268
sulfate
258
lysine
258
threonine
247
tyrosine
242
tryptophan
239
tryptophan
237
ammonia
232
tryptophan
229
tryptophan
229
potassium
216
urea
215
zinc
213
CO2
206
Insulin
192
proline
175
NAD
165
phosphoric acid
160
Ile
159
Phe
154
GTP
153
copper
151
isoleucine
150
isoleucine
147
ADP
141
valine
132
ADP
132
NAD
131
ADP
131
hexose
119
GSH
115
GSH
115
pyrimidine
114
pyrimidine
113
CoA
112
H2O2
111
hexose
109
hexose
109
hexose
109
NADPH
107
NADPH
107
manganese
105
NADH
102
acetyl-CoA
98
2-oxoglutarate
98
asparagine
97
nitric oxide
97
pentose
92
pentose
91
pentose
91
pentose
91
SDS
86
uridine
84
cadmium
79
NADP
76
iodine
74
TCA
72
acetic acid
71
Phytol
71
Phytol
71
TSH
65
MDA
64
Rapamycin
63
tetraphosphate
63
Mg2+
63
ornithine
62
ornithine
62
ornithine
62
Carbon
62
Sucrose
62
ornithine
62
ornithine
62
GDP
61
acetone
60
Asp
60
Gly
58
EDTA
57
H2S
57
alloxan
56
methanol
56
nicotinamide
56
EDTA
55
ACS
54
GlcNAc
53
ACS
53
malonyl-CoA
52
Glutamine
52
adenosylmethionine
52
cyanide
52
adenylate
51
xylose
48
noradrenaline
47
glutamic acid
47
TNF
47
boron
45
Glycogen
44
methane
44
MTT
43
PEG
42
creatinine
42
GMP
41
retinoic acid
41
ACTH
39
palmitic acid
39
acridine
39
TRH
38
TOF
38
salicylic acid
38
Cycloheximide
37
silver
37
bromide
36
MEK
36
homoserine
36
toluene
36
caffeine
35
homoserine
35
Guo
35
N-acetylcysteine
35
Glucagon
35
homoserine
35
silicon
34
Nitrate
33
phenol
33
homocysteine
32
ASC
32
Methionine
31
Serine
31
Cardiol
30
more...