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Query: UMLS:C0038187 (starvation)
 24,951 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Changes of the metabolic pool constitutents of Monosporium olivaceum -- a mould capable of steroid hydroxylation were examined. The experiments were carried during growth and starvation of the microorganism. The highest activity of the 11alpha-hydroxylase was observed in the mycelium which contained the lowest level of free amino acids, glucose, and mannitol. It is suggested that the inhibition of biosynthetic processes and the decrease of the respiration rate, the activity of the NAD(P)H regenerating systems maintained, provide the optimal physiological conditions for the activity of the steroid hydroxylases.
Acta Microbiol Pol 1976
PMID:Changes in the cellular content of the pool constituents of Monosporium olivaceum -- a steroid hydroxylating mould. 6 6

Teh effect of 48 hr food deprivation on noradrenaline (NA) and dopamine (DA) content in the dorsomedial, ventromedial and arcuate hypothalamic nuclei, in the anterior and posterior part of medial forebrain bundle, in the medial preoptic region, nucleus of diagonal band (septum), and in the central, medial and basal nuclei of the amygdaloid complex was investigated by radioenzymatic assay. It was found that starvation resulted in decreased NA and DA levels in arcuate and ventromedial nuclei, and increased DA content in the posterior medial forebrain bundle. A statistically insignificant increase of DA in the central amygdaloid nucl. was also observed.
Pol J Pharmacol Pharm
PMID:Hunger induced changes in the noradrenaline and dopamine contents in various nuclei of the limbic system in rats. 31 24

The experiments were carried out on broiler chickens divided randomly into two groups differing in the feeding level and, consequently, in the rate of weight gain. Half the chickens in each group were given a single dose of glucagon 150 micrograms/kg, and the other half received a control solution of glycine buffer. The chickens were investigated 1--1.5 hour after feeding and after 18--20 hours of starvation using the technique of biopsy of the liver and the external pectoral muscle. In the biopsy specimens the glycogen level was determined immediately before glucagon administration and 30--60--90 minutes after the injection. It was found that glucagon injection caused either a rise or a fall in the glycogen level in the liver and that the trend of these changes depended on the feeding level of the chickens and on the duration of starvation of the birds before treatment. The glycogen level in the pectoral muscle of the chickens kept on the higher feeding level was observed to fall one hour after glucagon administration.
Acta Physiol Pol
PMID:Glucagon effect on glycogen content of chicken liver and muscles. 50 56

The effect of intragastric glucose infusion (1.5 g per rat) to sated rats on the catecholamine content in the medial basal and lateral hypothalamic regions and in the nuclei of the amygdaloid body was investigated. The effect of glucose overloading on the noradrenaline (NA) and dopamine (DA) content in the ventromedial (VMH) and arcuate hypothalamic nuclei was also studied in rats deprived of food for 48 hr. Glucose administration to rats fed ad lib. resulted in an increase in NA in the VMH and a decrease in DA in the central nucleus of the amygdaloid body. In fasted animals glucose overloading partially reversed the changes of NA concentration in the arcuate nucleus produced by starvation, whereas in the VMH glucose was not effective in producing any changes of catecholamine content. Possible interrelations between the amygdala and hypothalamus in respect to the role of catecholamines in the regulation of food intake are discussed.
Pol J Pharmacol Pharm
PMID:The relationship between catecholamine levels in the hypothalamus and amygdala under influence of glucose overloading in hungry and sated rats. 52 39

Body weight and metabolic level in growing chickens. Acta Physiol. Pol., 1977, 28 (6): 575-583. In the investigations carried out on 128 White Rock chicken the metabolic level was determined under standard conditions in chickens characterising by different growth rate resulted from different feeding levels. It was shown that the feeding level of growing chicken has an essential influence on the character of the regression between the metabolic level and body weight. It was also found that this regression is not necessarily ot the character of Kleiber's function H = aWb. The differences in the metabolic level between the chickens maintained on different feeding levels did not disappear even after 4 days of starvation. In the light of the obtained results and recent investigations by other authors the usefulness of the so-called metabolic unit of the body size based on W0.75 in context to growing animals within one species has bee criticized.
Acta Physiol Pol
PMID:Body weight and metabolic level in growing chickens. 61 42

Growth hormone concentration has been assayed in 105 children (45 girls and 60 boys) during starvation and following its stimulation with clonidine and insulin and during the sleep. A significant difference between growth hormone concentration during fasting and after stimulation has been noted. No statistically significant difference between growth hormone concentrations during the sleep and following insulin has been found. The most intensive growth hormone release has been observed during the sleep. Test with clonidine is technically simple and may be performed also in the out-patient clinics.
Pol Tyg Lek
PMID:[Growth hormone concentration following various factors stimulating its release]. 130 18

The experiment was carried out on 15 calves of black and white breed at the age of 21-22 days. The effect of 72 hours simultaneous starvation and water deprivation on pharmacokinetics of antipyrine (phenazone) was studied. The following parameters were determined: Vd--volume of distribution, delta Vd--apparent volume of distribution, t0.5--half-life, ClA--metabolic clearance rate. There were shown statistically significant increase of half-life and decrease of metabolic clearance rate and volume of antipyrine distribution in fasted and water deprived calves. Apparent volume of antipyrine distribution in the control and experimental groups did not differ significantly. The obtained results indicate that starvation and water deprivation considerably inhibits liver biotransformation process (estimated on the basis of antipyrine test) in calves during neonatal period.
Arch Vet Pol 1992
PMID:Effect of short-term starvation and water deprivation on pharmacokinetics of antipyrine in calves. 133 67

Activity of the key enzymes of gluconeogenesis under alimentary thiamine deficiency (15 days of dietary treatment) was studied in the liver and kidney of fed and 48 h starved rats. As compared to pair-fed controls vitamin B1-deficiency was followed by a decrease of glucose 6-phosphatase and fructose 1,6-bisphosphatase activities in both organs; the activity of phosphoenolpyruvate carboxykinase was diminished only in the liver. Starvation of thiamine-deficient rats (as compared to pair-fed starved group) resulted in lower activation of these enzymes. The decrease of the enzyme activities in thiamine-deficient animals indicates that de novo glucose synthesis in the tissues is depressed, though thiamine-requiring enzymes are not directly involved in this process. Possible mechanisms of alterations described are discussed.
Acta Biochim Pol 1990
PMID:Effect of alimentary thiamine deficiency on the activity of gluconeogenic key enzymes in rat liver and kidney. 196 81

From 1975 to 1979, one to two million Cambodians were executed or died of disease and starvation during the rule of the Pol Pot government. In the aftermath of that catastrophe, many survivors have developed symptoms of post-traumatic stress disorder. There is some evidence that the intrusive symptoms of this disorder, such as nightmares, sleep disorders, and startle reactions, can be treated with medication. But other psychosocial problems that are similar to those found in chronic grief, such as avoidance behavior, shame, and decreased involvement with other individuals, are more resistive to treatment. On a cross-cultural level, the interpretations of, or meanings given to, specific symptoms by the patient may be influenced by culturally-specific religious beliefs, rituals, and social traditions. For the clinician, these cultural factors have relevance not only for engaging the patient in treatment, but also in the planning of specific therapeutic interventions.
 ...
PMID:Clinical relevance of grief and mourning among Cambodian refugees. 368 7

Intracerebroventricular (icv) injection of pentagastrin showed a powerful, dose dependent antidipsogenic effect in the rat. Drinking behavior stimulated by 48 h water deprivation was inhibited by 2000 ng of pentagastrin which also blocked, at lower doses, water intake induced by icv injection of angiotensin II (100 ng) and carbachol (150 ng). Pentagastrin was less effective on food intake stimulated by 24 h starvation. The antidipsogenic effect was not a consequence of behavioral alteration. It is suggested that gastrin-like peptides in the brain may play a role in the regulation drinking, acting as thirst inhibitors.
Pol J Pharmacol Pharm
PMID:Effect of intracerebroventricular injection of pentagastrin on rat drinking behavior. 408 Jun 44


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