Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038187 (
starvation
)
24,951
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The generation of a wide ESTs library and database from Trichoderma harzianum CECT 2413 was the base for identifying the gene ThPTR2, coding for a
PTR
family di/tri-peptide transporter. The deduced protein sequence of the ThPTR2 gene showed the conserved motifs and also the 12 transmembrane domains typical of the
PTR
transporters. The highest level of ThPTR2 expression was found when the fungus was grown in chitin as sole carbon source. We also found that ThPTR2 expression was increased when Trichoderma interacted directly in solid medium with the plant-pathogenic fungus Botrytis cinerea, showing that ThPTR2 is involved in the mycoparasitic process. Additionally, its expression was triggered by nitrogen
starvation
and a higher level of expression was also found when Trichoderma was grown in secondary nitrogen sources like allantoin, yeast extract, and urea. However, no difference was found when Trichoderma was grown in presence or absence of glucose as carbon source. Strain T34-15, a transformant that overexpressed the ThPTR2 gene, showed about a 2-fold increase in the uptake of the dipeptide Leu-Leu. Additionally, two transformants from the strain Trichoderma longibrachiatum T52 that overexpressed ThPTR2 were also studied, confirming the role of this gene in peptide transport. Other homologous genes to ThPTR2 were identified in other Trichoderma strains. ThPTR2 is the first experimentally confirmed
PTR
family transporter gene from filamentous fungi.
...
PMID:ThPTR2, a di/tri-peptide transporter gene from Trichoderma harzianum. 1646 53
Nitrate transporter 2.5 (NRT2.5) was originally characterized as the transporter for nitrogen (N) limitation. In
Arabidopsis, NRT2.5
is expressed mainly under extremely low NO
3
-
and N
starvation
conditions, and this must work in conjunction with NAR2.1.
NRT2.5
is expressed both in the roots and leaves in
Arabidopsis
, poplars, tea trees and cassava. This is also expressed in the seeds of
Arabidopsis
and wheat. In wheat,
NRT2.5
is expressed in the embryo and shell and plays a role in the accumulation of NO
3
-
in the seeds. In maize, this is also expressed in silk, cobs and tassel husk leaves. In rice,
OsNRT2.5
(also known as
OsNRT2.3a
) may help the species to remove NO
3
-
from the roots to shoots. In addition,
NRT2.5
may interact with
TGA3, MYC1, LBD37, LBD38, TaNAC2
and other transcription factors and participate in the transmission of NO
3
-
signals. The present review summarizes the functions of NRT2.5 in different plant species, which may help plant breeders and molecular biologists to improve crop yield.
Abbreviations:
NRT, Nitrate transporter; NUE, nitrogen use efficiency;
PTR
, peptide transporter; NPF, nitrate peptide transporter family; CLC, chloride channel; LAC1/SLAH, slow anion channel-associated 1 homolog 3; LATS, low-affinity transporter systems; HATS, high-affinity transport systems; NNP, nitrate-nitrite-porter; MFS, major facilitator superfamily.
...
PMID:The expression patterns and putative function of nitrate transporter 2.5 in plants. 3286 94
