Gene/Protein
Disease
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Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0038187 (
starvation
)
24,951
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
CDP-glycerol pyrophosphorylase, CDP-ribitol pyrophosphorylase and
poly(ribitol phosphate) synthetase
activities have been measured in cultures of Bacillus subtilis W23 as they became phosphate-starved either in batch culture or during changeover from potassium limitation to phosphate limitation in a chemostat. The results indicated that repression of synthesis of all three enzymes occurred at the onset of phosphate
starvation
and that this was accompanied by inhibition of inactivation of CDP-glycerol pyrophosphorylase and
poly(ribitol phosphate) synthetase
. These results show that the initial response to phosphate
starvation
involves more than inhibition of one enzyme as proposed by Glaser and Loewy [Glaser L. and Loewy, A. (1979) J. Biol. Chem. 254, 2184-2186]. Synthesis of both linkage unit and poly(ribitol phosphate) are inhibited independently.
...
PMID:Control of synthesis of wall teichoic acid in phosphate-starved cultures of Bacillus subtilis W23. 627 52
