Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038187 (starvation)
 24,951 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The lipogenic enzymes-6-phosphate dehydrogenase, citrate cleavage enzyme and malic enzyme of both liver and adipose tissue of rate of the wistar strain show a diminished activity in dependence on age. In the liver exists no age difference of the characteristic adaptation under the conditions of starvation and refeeding, but in adipose tissue of 18 months old rats the lipogenic enzymes show a poorer elevation of activity during refeeding after a 48 h period of starvation than in 3 months old animals. The serum inulin level and his variation in starvation and refeeding are independent of age.
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PMID:[Adaptation of lipogenic enzymes of liver and adipose tissue to starvation and refeeding (author's transl)]. 733 76

The specific activity of the citrate cleavage enzyme is 3.3 times greater in livers of obese mice than in livers of their nonobese litter mates. The difference persists during starvation. The specific activity of the acetate activating enzyme is approximately the same in the livers of both types of animals. It is proposed that a high activity of citrate cleavage enzyme is one of the factors responsible for obesity.
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PMID:CITRATE CLEAVAGE ENZYME IN LIVERS OF OBESE AND NONOBESE MICE. 1413 41