Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038187 (
starvation
)
24,951
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A patient with a monoclonal gammopathy, an erosive polyarthritis and a spastic
paraparesis
of both legs revealed a high titer of antinuclear antibodies with an immunofluorescence pattern hitherto unknown. A pleomorphic staining pattern of unsynchronized cells suggested a cell cycle-dependent autoantigen. Cell cycle-dependency of the antigen was confirmed by staining tissue sections, serum-
starvation
of tissue culture cells and mitogen-stimulation of peripheral blood lymphocytes. The antinuclear antibody does not belong to the paraprotein fraction of the serum immunoglobulins.
...
PMID:A novel cell cycle-dependent antinuclear antibody in a patient with a monoclonal gammopathy of unknown significance. 936 38
