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Query: UMLS:C0038187 (starvation)
 24,951 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Refeeding syndrome is a potentially fatal alteration in serum electrolytes occurring in patients refed after a period of starvation. Its actual incidence is not established due to lack of universally acceptable definitions. 88 years lady presented with negligible food intake for 15 days,mild dehydration and a BMI of 16.8kg/m2. Rigorous refeeding was started and patient developed hypophosphatemia, hypomagnesemia and ventricular premature contractions. Patient was diagnosed with refeeding syndrome and treatment was started. She recovered uneventfully and was discharged with nasogastric tube in situ on day 10 of admission. Refeeding syndrome is commonly encountered but mostly overlooked diagnosis and is a significant cause of nutritional morbidity and mortality in patients with chronic malnourishment. Keywords: Hypophosphatemia; refeeding; refeeding syndrome.
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PMID:Refeeding Syndrome. 3145 46

Refeeding syndrome (RFS) is the metabolic response to the switch from starvation to a fed state in the initial phase of nutritional therapy in patients who are severely malnourished or metabolically stressed due to severe illness. It is characterized by increased serum glucose, electrolyte disturbances (particularly hypophosphatemia, hypokalemia, and hypomagnesemia), vitamin depletion (especially vitamin B1 thiamine), fluid imbalance, and salt retention, with resulting impaired organ function and cardiac arrhythmias. The awareness of the medical and nursing staff is often too low in clinical practice, leading to under-diagnosis of this complication, which often has an unspecific clinical presentation. This review provides important insights into the RFS, practical recommendations for the management of RFS in the medical inpatient population (excluding eating disorders) based on consensus opinion and on current evidence from clinical studies, including risk stratification, prevention, diagnosis, and management and monitoring of nutritional and fluid therapy.
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PMID:Management of Refeeding Syndrome in Medical Inpatients. 3184 5


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