Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038187 (starvation)
24,951 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three out of 12,974 fowl in 13 floor pen tests spanning 7 years developed intestinal intussusceptions. Multiple (two separate) intussusceptions in the same bird and a single intussusception with prolapsed colon are conditions both reported for the second time only. One of the three birds had coccidiosis and two had coccidiasis. It is suggested on the basis of these and previously published data that the coccidiosis or coccidiasis sometimes associated with intussusceptions might develop secondarily following reduction of intake of food and, therefore, of anticoccidial agent, caused by the latter condition. Intussusception is probably not caused by starvation per se, since it is rarely associated with poultry diseases which cause primary anorexia. The morphology of the fowl's intestine probably makes invagination physically difficult and induction of an intussusception probably stems from an area of induration, exacerbated by any of several inconsistent predisposing factors. Probably no single cause of intestinal intussusception is identifiable.
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PMID:On the aetiology of intestinal intussusception in the fowl. 1876 29

In a flock of 1017 pullets aged 7 weeks feeding was reduced from 2 to 0.5 bags a day due to feed scarcity. The pullets became weak and some died 5 days later. Necropsy showed duodenal coccidiosis, often an empty gastro-intestinal tract and intussusception of the ileum near the ileocaecal junction. The tips of the caecae and/or their mesentery were often telescoped into the ileum. Affected areas were inflamed, necrotic and often gangrenous and sloughing. On another farm with 328 pullets of 12-weeks-old intussusception of the ileum near the ileocaecal junction was again observed when feeding was reduced from two bags in 3 days to 1 in 5 days. The caecae and/or their mesentery were also involved. Examinations for coccidiosis gave negative results. These observations indicate that starvation may cause intestinal intussusception in fowls.
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PMID:Cases of intestinal intussusception in young fowls. 1876 21

Juvenile polyposis of infancy is a rare genetic disorder, involving multiple hamartomatous polyps of the gastrointestinal tract, which usually has a very aggressive clinical course and is often fatal. It is characterized by early onset (during the 1st months of life) and by diffuse juvenile polyposis with anemia, recurrent gastrointestinal bleeding, diarrhea, rectal prolapse, intussusception, protein-losing enteropathy, starvation, and malnutrition. There is a hypothesis that mutation of the tumor-suppressor genes BMPR1A and PTEN, located on the long arm of chromosome 10, is associated with the development of this disease. Medical treatment for this disorder is challenging and should be conservative whenever possible. We present the case of a 3-year-old girl with juvenile polyposis of infancy who eventually died from mesenteric artery thrombosis during surgical colectomy. Karyotype of the patient showed a paracentric inversion in 10q and a deletion in 10p. We will briefly comment on some genetic considerations of this disease.
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PMID:Juvenile polyposis of infancy associated with paracentric inversion and deletion of chromosome 10 in a Hispanic patient: a case report. 2033 46