Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038002 (splenomegaly)
 9,873 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 59 years old man jaundice, haemathologic disturbances and Splenomegaly, with epilepsy treated by Carbamazepine in the last 3 weeks is reported. He had a positive response to withdrawal carbamazepine and corticotherapy.
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PMID:[Carbamazepine-induced hepatitis. A case report]. 1059 4

Carbamazepine is an antiepileptic drug. In clinical trials the total incidence of reported adverse reaction to this drug is 4.5 per million at defined daily doses, corresponding to 2.7 per million at prescribed daily doses. Among the adverse reactions of carbamazepine, most often reported are skin reactions (48%), hematological (14%), hepatic disorder (10%). Herein, we present a case with erythematous skin rashes and hepato-splenomegaly.
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PMID:Carbamazepine-induced hepato-splenomegaly with erythematous rashes in a child. 2252 91