Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038002 (
splenomegaly
)
9,873
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Marked increases in
phospholipase B
activity were measured in spleen homogenates and sera of CD-1 mice given a primary infection of Plasmodium yoelii. The rise in enzyme activity paralleled parasitemia and
splenomegaly
, all reaching maximum values 14 days after infection. Maximum enzyme activity and
splenomegaly
were noted 5 days after challenge in mice given a secondary infection indicating an anamnesticlike response following a subsequent contact with the infecting parasite. These observations represent a new finding of this enzyme activity in a protozoan infection.
...
PMID:Elevated levels of phospholipase B in mice infected and challenged with Plasmodium yoelii. 713 Nov 82
