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Query: UMLS:C0038002 (splenomegaly)
 9,873 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors describe one case of stenosis of the common hepatic artery associated with splenomegaly. After commenting on the rarity and peculiarity of such an occurrence, they explain the decisive role of selective celiac tripod arteriography not only for precise diagnostic definition of the case but also in terms of formulating an appropriate therapeutic program. The study of this case includes a detailed exploration of the hemodynomic situation created by the anomaly in the hepatosplenic district, and an equally detailed study of the associated blood picture changes.
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PMID:[Stenosis of hepatic artery associated with portal vein anomaly and splenomegaly: a haemodynamic evaluation (author's transl)]. 54 Mar 84

Selective celiac and superior mesenteric arteriographies were performed in patients with portal hypertension. An arterioarterial (A-A) shunt between the superior mesenteric artery and the celiac axis via pancreatic arcades was found in fifteen of forty-three patients with associated massive splenomegaly. A mild A-A shunt disappeared after portacaval anastomosis alone, whereas a prominent A-A shunt was reduced but persisted. The persisting A-A shunt disappeared after splenectomy. These findings led us to suggest that the paucity of the blood flow in the common hepatic artery concomitant with increased splenic arterial flow to the massively enlarged spleen may result in a compensatory supply to the liver from the superior mesenteric artery via the shunt.
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PMID:Significance of selective arteriographic patterns in the celiac axis and superior mesenteric artery in portal hypertension. 98 16

Severe splenomegaly and anemia developed in a 5-year-old girl with diffuse lymphangiomatosis of the upper part of the body. Radioisotope scanning and celiac angiography demonstrated lymphangiomatosis of the spleen, a rare but diagnosable condition. Intractable infection in areas of ulcerated skin led to her death from overwhelming sepsis.
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PMID:Lymphangiomatosis with splenic involvement. 98 35

Of 21 patients with cirrhosis of the liver 9 had collateral arterial flow to the liver from the superior mesenteric artery. The degree of collateral arterial flow in cirrhosis was related to the presence of centrifugal portal flow, the degree of bilirubinemia and the presence of a markedly enlarged spleen with increased splenic blood flow. Of 27 non-cirrhotic 6 had collateral arterial flow to the liver from the superior mesenteric artery. The greatest degree of collateral arterial flow was associated with celiac stenosis in 4/6 patients. One patient had pancreatitis and an explanation was not evident in one patient.
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PMID:The arterial blood supply to the liver in cirrhosis. 105 62

A focal avascular defect in an enlarged spleen, clearly shown both by 99mTc-sulfur colloid scanning and by celiac angiography, could not be associated with any gross pathologic abnormality at splenectomy. Vascular lesions can probably produce focal defects on the scan in the absence of infarction.
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PMID:Arteriographically confirmed focal defect in colloid spleen scan with no gross pathologic lession: case report. 126 41

Clinically, idiopathic portal hypertension (IPH) is characterized by overt splenomegaly with pancytopenia, portal hypertension and relatively mild abnormalities in liver function tests. Although its etiology is still undetermined, the liver pathology is characterized by occlusive changes of the intrahepatic portal radicles, portal and periportal fibrosis, irregularly distributed parenchyma atrophies and absent of regeneration nodules. The disease is relatively benign and does not progress to cirrhosis. Differential diagnosis between IPH and liver cirrhosis is mandatory. We now report a case with histologically proven IPH, including clinical course, laboratory data, roentgenographic findings of hepatic venogram and celiac angiogram, hepatic hemodynamic features and intravariceal pressure of esophageal varix which has never been reported in Taiwan.
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PMID:Idiopathic portal hypertension: a case report. 132 89

We describe the case of a 42 year old woman with abdominal pain, ascites, and splenomegaly after having taken dihydroergotamine continuously for three months due to frequent hemicranic episodes. The celiac-mesenteric angiography demonstrated diffuse thrombosis of splenic, superior mesenteric and portal veins. No surgical intervention was possible. We believe that it is possible that dihydroerogotamine, a hydrogenated derivative of ergotamine, inasmuch as it is capable of causing peripheral vasoconstriction, intimal lesions, arterial and venous thrombi, was also the cause of our patient's portal thrombosis. We therefore suggest the minimum effective amount of the drug be utilized to achieve the relief of cephalalgia.
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PMID:A case of portal thrombosis arisen after treatment with dihydroergotamine. 175 20

Ultrasound investigation of the abdominal vessels (the celiac artery and its branches, the hepatic veins and the portal veins) was performed in 30 patients with cholelithiasis, 20 patients with chronic acalculous cholecystitis and 100 healthy controls. Statistically significant increases in the calibers of the hepatic arteries and portal veins were detected in the patients with cholelithiasis. The diameters of these vessels in the patients with chronic acalculous cholecystitis did not differ considerably from those of the controls. Ascites, splenomegaly, vascular collaterals, varicosis of the esophageal or gastric veins were unobserved in the patients with cholelithiasis, neither was observed an increase in the calibers of the portal veins during the Valsalva test in this group as compared to the control group. It was assumed that an increase in the calibers of the hepatic vessels in cholelithiasis was caused by change in the hepatic blood flow rather than by the development of portal hypertension.
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PMID:[Ultrasonic evaluation of the state of the abdominal vessels in cholelithiasis and chronic acalculous cholecystitis]. 266 51

A 64-year-old man with cirrhosis of the liver had a palpable, pulsatile palm-size mass over the upper abdomen. Splenic artery aneurysm was diagnosed by sonography, computed tomography scan, and celiac angiography. Operative findings showed a huge splenic artery aneurysm (20 X 30 X 20 cm) over the middle portion of the splenic artery. Such a huge splenic artery aneurysm may develop because changes in splenic circulatory dynamics after a portocaval shunt, resulting in compression of the splenic vein and congestive splenomegaly.
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PMID:Huge splenic artery aneurysm after portocaval shunt. 318 29

We report herein the case of a 47-year-old man who developed a huge splenic artery aneurysm (SAA) with splenomegaly, for which ligation of the splenic artery and partial aneurysmectomy was performed. A celiac arteriogram taken 2 months postoperatively revealed that two small aneurysms had developed in the collateral vessels, indicating that increased blood flow through the collateral circulation could be responsible for the formation of secondary aneurysms. This postoperative change suggests that the etiology is related to the SAA and thus, the possibility that aneurysms may develop in the collateral vessels following spleen-preserving procedures for SAA must be borne in mind and careful follow-up performed at regular intervals.
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PMID:Recurrent splenic artery aneurysms developing after aneurysmectomy without splenectomy: report of a case. 777 22


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