Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0037315 (sleep apnea)
 8,000 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
Calcium/calmodulin-dependent protein kinase ID 12.0
GTPase activating protein and VPS9 domains 1 11.0
AHDC1 10.4
Zinc finger protein 36 10.0
CPAP 9.6
TARS2 9.4
GAPVD1 9.4
ZNF462 9.0
PIBF1 9.0
ORP9 8.8
PRPF40A 8.8
PSG2 8.5
EDR3 8.4
PSG 8.4
Hoxb-13 8.3
CD3EAP 8.3
DLEU7 8.2
hPER2 8.1
CSR 8.0
iduronate-2-sulphatase 7.9
CT90 7.9
POGZ 7.6
CAMK1D 7.6
REM 7.5
MAGEL2 7.4
RAI1 7.4
Nuclear respiratory factor 1 7.3
PLOD3 7.3
STOP 7.1
SIDS 7.1
hSyn 7.1
MEMO 7.1
NEDD1 7.0
PSG1 7.0
C4BPA 6.9
beta1,3-galactosyltransferase 6.9
monocarboxylate transporter 2 6.8
putative nuclear factor 6.7
CSA 6.7
PTGER3 6.6
mPR 6.6
ASH1L 6.5
MASK 6.5
EDR1 6.4
MATR3 6.3
pycnodysostosis 6.3
QRFP 6.3
LTF 6.3
PIAS4 6.3
MKS 6.3
acetyl-CoA carboxylase 2 6.2
MsrB3 6.2
AHI1 6.1
OPT 6.1
MPS II 6.1
ms2 6.0
ZBTB7A 6.0
iduronate-2-sulfatase 5.9
ACVR2A 5.9
CLTC 5.9
natriuretic peptide receptor B 5.9
NFATc3 5.8
MAP2K2 5.8
HELIOS 5.8
ARSB 5.8
NKB1 5.7
PLM 5.7
MNK 5.7
PAFR 5.7
ESM-1 5.7
melanoma inhibitory activity 5.6
IDUA 5.6
SNA 5.6
DNA damage-inducible protein 5.6
TNR 5.5
FMR2 5.4
PDHA1 5.4
FIF 5.4
HHH 5.4
CX3C chemokine receptor 1 5.4
more...
Disease
High altitude periodic breathing 12.0
Subglottic obstruction 12.0
Secondary restless legs syndrome 12.0
sleep apnea 12.0
pathological emotionality 12.0
Insufficient sleep syndrome 11.4
Sleep drunkenness 11.0
Scalloped tongue 11.0
Primary alveolar hypoventilation 11.0
Central sleep apnea 10.9
Other sleep disorders 10.7
Upper airway resistance syndrome 10.7
disorders of initiating or maintaining sleep 10.4
Idiopathic Hypersomnia 10.4
Epiglottic cyst 10.0
Nonarteritic ischemic optic neuropathy 9.6
Sleep-related painful erections 9.6
Obesity hypoventilation syndrome 9.6
obstructive sleep apnea 9.4
tonsillar hypertrophy 9.2
Floppy eyelid syndrome 9.1
Mandibular retrognathism 9.0
Ondine's curse 8.9
Ondine's curse 8.8
Nasopharyngeal stenosis 8.8
sleep disorders 8.8
Generalized obesity 8.6
Upper airway obstruction 8.6
sleep terrors 8.6
narcolepsy 8.6
parasomnia 8.5
Tracheal obstruction 8.4
restless legs syndrome 8.4
Chronic respiratory failure 8.4
Benign neonatal sleep myoclonus 8.4
partial monosomy 6q 8.4
Perennial allergic rhinitis 8.3
infantile apnea 8.3
sleepwalking 8.1
REM sleep behavior disorder 8.1
ethanolism 8.1
Multiple symmetrical lipomatosis 8.1
Chronic paroxysmal hemicrania 8.0
Cough syncope 8.0
Hypothalamic dysfunction 7.9
recurrent tonsillitis 7.8
Recurrent apnea 7.8
Pycnodysostosis 7.7
Severe hypothyroidism 7.7
claustrophobia 7.7
adenoiditis 7.6
Thornwaldt 7.6
Primary insomnia 7.6
cataplexy 7.5
sleep disturbances 7.5
sexual dysfunction and infertility 7.4
Hypopharynx 7.4
Transient epileptic amnesia 7.4
postpolio syndrome 7.4
Cor Pulmonale 7.3
Sleep disturbance 7.2
Diabetic autonomic neuropathy 7.2
Gerhardt 7.1
Kleine-Levin syndrome 7.1
Myhre syndrome 7.1
NARES 7.1
syringobulbia 7.0
Secondary pulmonary hypertension 7.0
Overlap syndrome 7.0
nocturia 7.0
secondary polycythemia 6.9
Mauriac syndrome 6.9
Chronic congestive heart failure 6.9
chronic tonsillitis 6.8
behavior disorder 6.8
OHS 6.7
CSA 6.7
Craniometaphyseal dysplasia 6.7
Negative pressure pulmonary edema 6.7
peritonsillitis 6.7
more...
Symptom
Morning headache 10.6
snoring 10.4
Hypersomnolence 9.9
CSR 9.7
Nocturnal angina 9.6
feeling of choking 9.6
Persistent insomnia 9.0
hypersomnia 8.9
abnormal breathing 8.7
Respiratory abnormalities 8.6
eds 8.5
Periodic breathing 8.5
sleepiness 8.4
Neuromuscular weakness 8.3
nocturnal polyuria 8.2
dry throat 8.2
Kussmaul's sign 7.6
Poor sleep 7.4
Lung hyperinflation 7.2
insomnia 7.1
hypercapnia 6.9
Mouth breathing 6.9
bedwetting 6.9
respiratory problem 6.9
Orthostasis 6.8
bradypnea 6.6
situational stress 6.6
hypocapnia 6.5
enuresis 6.4
Nasal symptoms 6.3
stridor 5.9
breath holding 5.8
feeling tired 5.7
nasal congestion 5.4
sighing 5.4
ENT 5.3
cardiovascular impairment 5.2
No pain 5.2
Visual symptoms 5.2
orthopnea 5.1
hypotonia 5.1
lightheadedness 5.0
myoclonus 4.9
body pain 4.9
leg edema 4.9
collapse 4.7
orofacial pain 4.6
throat irritation 4.5
peri-menopausal 4.5
overweight 4.4
loss of taste 4.4
catarrh 4.4
generalized pain 4.3
Fluctuation 4.3
asterixis 4.3
labored breathing 4.2
drooling 4.2
inanition 4.2
forgetfulness 4.1
blackout 4.1
motor symptom 4.1
fatigue 4.1
chronic cough 4.0
postnasal drip 3.9
heartburn 3.9
male subfertility 3.9
distraction 3.9
sneezing 3.9
personality change 3.8
dyspnea 3.8
dark urine 3.8
lassitude 3.8
halitosis 3.7
cyanosis 3.7
dysarthria 3.7
Sedation 3.6
nasal discharge 3.5
hyperoxia 3.5
joint stiffness 3.5
tachypnea 3.5
more...
Drug
Galsulfase 9.4
Aldurazyme 8.8
Aldurazyme 8.8
Idursulfase 8.6
Xyrem 8.1
Tilade 7.9
Armodafinil 7.6
Modafinil 7.5
Equipoise 7.5
Remeron 7.4
Pegvisomant 7.2
Tryptophane 7.0
Anafranil 5.9
Ramelteon 5.6
MINO 5.5
Orlistat 5.4
Atrovent 5.3
Anafranil 5.2
Ketorolac tromethamine 5.2
Tapentadol 5.1
Fluticasone propionate 5.1
PNT 4.9
Diurnal 4.8
NLF 4.7
Mirtazapine 4.7
ENT 4.7
Methyldopa 4.6
Nadolol 4.6
AVC 4.5
Agomelatine 4.4
Nedocromil sodium 4.4
Zonisamide 4.4
Omalizumab 4.3
Pramipexole 4.3
Ipratropium bromide 4.2
Pramipexole 4.2
Liraglutide 4.2
DM1 4.1
Growth hormone 4.0
Theophylline 4.0
Android 3.9
Triazolam 3.9
Check 3.8
IPD 3.7
Exenatide 3.6
Rimonabant 3.6
Ritalin 3.6
Growth hormone 3.6
Codeine 3.5
Codeine 3.4
Allergen 3.4
Xanthium 3.3
Atenolol 3.2
Diclofenac sodium 3.2
DEX 3.1
Singular 3.0
Propofol 2.9
Digitalis 2.7
Triad 2.7
Domperidone 2.6
Triad 2.5
Camp 2.5
ROC 2.2
DBS 2.2
Gabapentin 2.2
Gastro 2.1
Cetuximab 2.1
DDAVP 2.1
DDAVP 2.0
TAK 2.0
Clopidogrel 1.9
Spectrum 1.8
Phentolamine 1.8
Horizon 1.7
Serum albumin 1.7
DPA 1.6
CTC 1.6
CCL 1.6
Lovastatin 1.6
Phenytoin 1.6
more...
Enzyme
iduronate-2-sulfatase 5.6
acetylserotonin O-methyltransferase 5.2
alpha-L-iduronidase 5.0
NAO 4.5
SPT 3.9
ACAT 3.5
PAT 3.2
FFT 3.2
SPT 3.1
O-GlcNAc transferase 3.0
cystathionine gamma-lyase 2.9
p80 2.9
renin 2.8
thromboxane synthase 2.8
phenylethanolamine N-methyltransferase 2.7
cathepsin K 2.7
chymase 2.6
carbonic anhydrase 2.6
DAT 2.4
CAD 2.2
CAD 2.2
caspase-7 2.2
LasR 2.2
IMP dehydrogenase 2.1
CAD 2.1
caspase-7 2.1
BIS 2.1
GAS 2.1
cystathionine beta-synthase 2.0
ADH 1.8
myosin ATPase 1.8
NADPH oxidase 1.4
MAP 1.4
sialyltransferase 1.4
sialyltransferase 1.4
sialyltransferase 1.4
CPT 1.3
NADPH oxidase 1.3
paraoxonase 1.2
CPT 1.2
glycerol-3-phosphate dehydrogenase 1.2
tryptophan hydroxylase 1.2
glycerol-3-phosphate dehydrogenase 1.1
prolyl hydroxylase 1.1
ACE 1.1
TdT 1.1
cholesterol acyltransferase 0.9
paraoxonase 0.9
heme oxygenase 0.9
choline acetyltransferase 0.9
methylenetetrahydrofolate reductase 0.9
methylenetetrahydrofolate reductase 0.9
chondroitinase 0.9
PDK1 0.8
GSK 0.8
CPT 0.8
CDR 0.7
PKG 0.7
hypoxanthine-guanine phosphoribosyltransferase 0.7
NO synthase 0.6
AST 0.4
phosphodiesterase 0.3
sulfatase 0.3
calcineurin 0.2
HSD 0.2
aspartate aminotransferase 0.1
PDE 0.1
alanine aminotransferase 0.1
acetylcholinesterase -0.0
proteinase K -0.0
succinate dehydrogenase -0.0
cholinesterase -0.1
alpha-glucosidase -0.1
alcohol dehydrogenase -0.2
CD10 -0.3
MIP -0.3
tyrosine hydroxylase -0.3
tissue plasminogen activator -0.5
phosphoinositide 3-kinase -0.6
caspase-1 -0.7
more...
Compound
DNPD 12.0
Protriptyline 8.4
Phentermine 5.9
CLTC 5.9
Acetazolamide 5.8
CHQ 5.7
Nalmefene 5.6
Sibutramine 5.2
SD 25 5.2
ADMA 5.2
Tamsulosin 5.0
Trazodone 5.0
MIT 4.9
AIR 4.9
MIT 4.9
PNT 4.9
Clonazepam 4.8
Pyridostigmine 4.5
MNE 4.5
Gallamine 4.5
CUE 4.5
Aminophylline 4.5
Phenothiazine 4.4
Esmolol 4.4
11-dehydro-thromboxane 4.4
Prone 4.4
Bisoprolol 4.3
Clomipramine 4.3
SHB 4.3
Zonisamide 4.3
Bepridil 4.3
Nitrazepam 4.3
Tempol 4.2
PAP 4.1
Inactin 4.1
Geigy 4.1
Salmeterol 4.0
Cabergoline 4.0
Mirtazapine 3.9
PAP 3.9
PAP 3.9
NCD 3.9
MAD 3.8
Theophylline 3.8
PAP 3.8
Trimethylamine N-oxide 3.8
2-nonenal 3.8
Montelukast 3.8
HMS 3.8
IPD 3.8
Ritalin 3.7
Succinylcholine 3.7
MSL 3.7
Meperidine 3.6
Codeine 3.5
Fenfluramine 3.5
Domperidone 3.5
Desmopressin 3.4
oxygen 3.4
DMD 3.4
PAT 3.4
HAQ 3.3
PAG 3.3
Methylphenidate 3.3
PMS 3.3
Dexmedetomidine 3.2
CO2 3.2
DEX 3.2
Selectin 3.1
Zolpidem 3.1
MAOA 3.1
SVC 3.1
DBT 3.1
8-OHdG 3.1
BIC 3.1
Buspirone 3.0
Flumazenil 3.0
Testosterone 3.0
Quetiapine 3.0
Tanshinone 3.0
more...