Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0037315 (
sleep apnea
)
8,000
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
550
REM
250
CPAP
250
insulin
234
CO2
123
renin
64
growth hormone
59
MRI
56
leptin
55
ENT
53
COPD
46
CSA
45
She
43
Mol
38
Mal
36
Pol
35
hemoglobin
31
natriuretic peptide
31
cytokine
30
SAS
30
IL-6
29
PSG
28
orexin
28
CSR
27
C-reactive protein
25
STOP
24
cage
22
interleukin-6
22
erythropoietin
20
tumor necrosis factor
19
lymphoid
19
SIDS
19
angiotensin II
19
TNF-alpha
18
ANOVA
18
TNF
18
adiponectin
18
reserved
17
somatostatin
15
chronic renal failure
15
Leptin
15
endothelin-1
14
atrial natriuretic peptide
13
thyroid hormone
12
gut
12
ICD
12
PAP
12
Men
12
CSF
11
HDL
11
CRP
11
FEV
11
nitric oxide synthase
10
carbonic anhydrase
10
resistin
10
dream
10
HLA
9
X-linked
9
vascular endothelial growth factor
9
MPS II
9
Growth hormone
9
ATP
9
TCS
8
SNA
8
IGF-I
8
Gen
8
P300
8
albumin
8
ghrelin
8
ET-1
8
vasopressin
8
DM1
8
prolactin
7
GABA
7
axonal
7
IL-8
7
endoplasmic reticulum
7
NMDA receptor
7
collagen
7
IGF-1
6
more...
Disease
sleep apnea
8000
obstructive sleep apnea
1699
hypertension
1067
obesity
1005
sleep disorders
757
diabetes
475
heart failure
443
depression
364
stroke
339
cardiovascular disease
336
narcolepsy
251
sleep disturbances
244
chronic obstructive pulmonary disease
226
type 2 diabetes
189
pulmonary hypertension
177
restless legs syndrome
164
congestive heart failure
156
asthma
155
metabolic syndrome
142
respiratory failure
123
coronary artery disease
114
cognitive impairment
109
cancer
103
epilepsy
100
atherosclerosis
94
heart disease
94
gastroesophageal reflux disease
93
sudden infant death syndrome
92
dementia
87
acromegaly
85
myocardial infarction
77
renal disease
75
dyslipidemia
75
morbid obesity
72
Central sleep apnea
72
myocardial ischemia
71
coronary heart disease
67
Alzheimer's disease
65
osteoarthritis
62
Parkinson's disease
61
lung disease
57
respiratory disease
56
movement disorder
54
SEM
54
hypothyroidism
53
Syndrome
52
hyperlipidemia
51
tumor
51
polycystic ovary syndrome
49
cor pulmonale
49
cataplexy
49
ventricular hypertrophy
48
Down syndrome
47
dysphagia
46
Thorax
46
COPD
46
CSA
45
migraine
44
cardiomyopathy
43
glucose intolerance
42
nocturia
39
DM1
36
ischemia
36
tonsillar hypertrophy
35
pulmonary edema
35
chronic pain
35
renal failure
34
chronic disease
32
parasomnia
32
REM sleep behavior disorder
32
right heart failure
31
fatty liver
31
Sleep disturbance
30
hypogonadism
30
vascular disease
29
anemia
29
pneumonia
28
bruxism
28
cold
27
neuropathy
27
more...
Symptom
sleepiness
1061
snoring
981
insomnia
365
hypercapnia
246
fatigue
217
collapse
186
anesthesia
168
pain
161
overweight
143
CSR
143
hypersomnia
129
headache
127
dyspnea
100
seizures
98
eds
97
weakness
71
cough
53
ENT
53
hypotonia
51
discomfort
40
discomfort
40
hypocapnia
38
enuresis
36
stridor
36
distraction
35
myoclonus
33
respiratory distress
33
ataxia
27
analgesia
26
angina
24
abnormal breathing
23
tremor
18
syncope
18
agitation
18
hyperoxia
15
Poor sleep
15
lethargy
14
arthralgia
14
dysarthria
12
nasal congestion
12
cyanosis
12
shortness of breath
11
nocturnal polyuria
11
vomiting
11
nausea
11
wheezing
10
dystonia
10
regurgitation
10
cerebellar ataxia
9
bedwetting
9
Periodic breathing
8
spasm
8
constipation
8
chronic cough
8
breath holding
8
heartburn
8
chest pain
8
hypothermia
7
exhaustion
7
sneezing
7
tachypnea
7
memory loss
7
dizziness
7
orofacial pain
6
sore throat
6
polyuria
6
tinnitus
6
spasticity
6
back pain
6
exertional dyspnea
6
hepatosplenomegaly
6
hunger
5
abdominal pain
5
bradypnea
5
rhinorrhea
5
leg edema
5
stigma
5
vertigo
4
Morning headache
4
nasal discharge
4
more...
Drug
Cardiovasc
57
ENT
54
Modafinil
18
Asthma
18
caffeine
15
Growth hormone
12
Diurnal
12
CSF
11
Monit
11
Dial
10
ROC
9
Growth hormone
9
Theophylline
8
Spectrum
7
Dermatol
7
Check
7
DM1
7
MAP
7
Nephron
7
ROS
5
Nephron
4
Orlistat
4
nitroglycerin
4
Propofol
4
Allergen
4
vitamin E
3
Spectrum
3
Pegvisomant
3
Android
3
Atenolol
2
Xanthium
2
CTX
2
DEX
2
ABC
2
Omalizumab
2
Ethanol
2
Mirtazapine
2
Aldurazyme
2
Idursulfase
2
IL-2
2
Albumin
2
Liraglutide
2
Aldurazyme
2
Zonisamide
2
Angiotensin II
2
Atropine
2
Leaf
2
Xyrem
2
DDAVP
1
Glutathione
1
MINO
1
niacin
1
Clopidogrel
1
Domperidone
1
DPA
1
Triad
1
Codeine
1
Agomelatine
1
ETA
1
Equipoise
1
Anafranil
1
Dakar
1
Galsulfase
1
Methyldopa
1
Anafranil
1
Ketorolac tromethamine
1
NLF
1
Frontal
1
ADM
1
Phenytoin
1
Clonidine
1
Serum albumin
1
Horizon
1
Ramelteon
1
MDS
1
Phentolamine
1
Tilade
1
Gabapentin
1
Nitric Oxide
1
Ipratropium bromide
1
more...
Enzyme
renin
64
carbonic anhydrase
11
ACE
10
mitogen-activated protein kinase
9
superoxide dismutase
8
protein kinase
8
ERK
8
acetylcholinesterase
7
NADPH oxidase
7
alanine aminotransferase
7
protein kinase C
7
NADPH oxidase
7
phosphodiesterase
6
aspartate aminotransferase
6
NO synthase
6
CAD
5
calcineurin
5
CAD
5
ATPase
5
MAP
5
CAD
5
catalase
5
thrombin
3
cathepsin K
3
alpha-L-iduronidase
3
cholinesterase
3
choline acetyltransferase
3
glutathione peroxidase
3
lactate dehydrogenase
3
GSK
3
iduronate-2-sulfatase
3
caspase-3
3
tyrosine hydroxylase
3
DAT
2
AST
2
alkaline phosphatase
2
CPT
2
creatine kinase
2
lipase
2
tissue plasminogen activator
2
FFT
2
focal adhesion kinase
2
chymase
2
CPT
2
luciferase
2
alcohol dehydrogenase
2
PAT
2
ADH
2
peroxidase
2
CPT
2
heme oxygenase
2
AMP-activated protein kinase
2
CD10
2
adenylate cyclase
2
succinate dehydrogenase
2
phospholipase C
2
SPT
2
SPT
2
lysozyme
1
myosin ATPase
1
proteasome
1
NAO
1
cystathionine beta-synthase
1
alpha-glucosidase
1
cytochrome oxidase
1
paraoxonase
1
prolyl hydroxylase
1
proteinase K
1
IMP dehydrogenase
1
tryptophan hydroxylase
1
caspase-7
1
glycerol-3-phosphate dehydrogenase
1
O-GlcNAc transferase
1
caspase-8
1
cystathionine gamma-lyase
1
ACAT
1
caspase-9
1
AMPK
1
PKG
1
HSD
1
more...
Compound
oxygen
982
Clin
723
Dec
635
CO2
206
glucose
142
Cardiol
122
water
112
sodium
50
nitric oxide
46
His
46
aldosterone
41
calcium
33
DNA
31
ethanol
27
Insulin
23
creatinine
22
potassium
21
iron
20
salt
20
noradrenaline
19
Optimal
19
TNF
18
5-HT
15
caffeine
15
MIT
13
homocysteine
13
acetate
13
MIT
13
Acetazolamide
12
PAP
12
PAP
12
Testosterone
12
PAP
12
PAP
12
Testosterone
12
phosphate
10
Thyroid
10
nitrogen
10
DSM
10
Dial
10
Theophylline
10
glutamate
9
arginine
9
6-12
9
ATP
9
silver
8
GABA
7
Melatonin
7
tryptophan
7
H2S
7
8-OHdG
7
tryptophan
7
tryptophan
7
tryptophan
7
hydrogen
7
GABA
7
MAP
6
SO2
6
2-nonenal
6
Nicotine
6
ASA
6
Angiotensin II
6
urea
6
acrylamide
5
cAMP
5
A 42
5
sulfate
5
cysteine
5
SDS
4
ANS
4
PAS
4
Propofol
4
zinc
4
barium
4
Cholesterol
4
DBP
4
dUTP
4
DDD
4
Androgen
4
DBP
4
more...