Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0037315 (sleep apnea)
8,000 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 550
REM 250
CPAP 250
insulin 234
CO2 123
renin 64
growth hormone 59
MRI 56
leptin 55
ENT 53
COPD 46
CSA 45
She 43
Mol 38
Mal 36
Pol 35
hemoglobin 31
natriuretic peptide 31
cytokine 30
SAS 30
IL-6 29
PSG 28
orexin 28
CSR 27
C-reactive protein 25
STOP 24
cage 22
interleukin-6 22
erythropoietin 20
tumor necrosis factor 19
lymphoid 19
SIDS 19
angiotensin II 19
TNF-alpha 18
ANOVA 18
TNF 18
adiponectin 18
reserved 17
somatostatin 15
chronic renal failure 15
Leptin 15
endothelin-1 14
atrial natriuretic peptide 13
thyroid hormone 12
gut 12
ICD 12
PAP 12
Men 12
CSF 11
HDL 11
CRP 11
FEV 11
nitric oxide synthase 10
carbonic anhydrase 10
resistin 10
dream 10
HLA 9
X-linked 9
vascular endothelial growth factor 9
MPS II 9
Growth hormone 9
ATP 9
TCS 8
SNA 8
IGF-I 8
Gen 8
P300 8
albumin 8
ghrelin 8
ET-1 8
vasopressin 8
DM1 8
prolactin 7
GABA 7
axonal 7
IL-8 7
endoplasmic reticulum 7
NMDA receptor 7
collagen 7
IGF-1 6
more...
Disease
sleep apnea 8000
obstructive sleep apnea 1699
hypertension 1067
obesity 1005
sleep disorders 757
diabetes 475
heart failure 443
depression 364
stroke 339
cardiovascular disease 336
narcolepsy 251
sleep disturbances 244
chronic obstructive pulmonary disease 226
type 2 diabetes 189
pulmonary hypertension 177
restless legs syndrome 164
congestive heart failure 156
asthma 155
metabolic syndrome 142
respiratory failure 123
coronary artery disease 114
cognitive impairment 109
cancer 103
epilepsy 100
atherosclerosis 94
heart disease 94
gastroesophageal reflux disease 93
sudden infant death syndrome 92
dementia 87
acromegaly 85
myocardial infarction 77
renal disease 75
dyslipidemia 75
morbid obesity 72
Central sleep apnea 72
myocardial ischemia 71
coronary heart disease 67
Alzheimer's disease 65
osteoarthritis 62
Parkinson's disease 61
lung disease 57
respiratory disease 56
movement disorder 54
SEM 54
hypothyroidism 53
Syndrome 52
hyperlipidemia 51
tumor 51
polycystic ovary syndrome 49
cor pulmonale 49
cataplexy 49
ventricular hypertrophy 48
Down syndrome 47
dysphagia 46
Thorax 46
COPD 46
CSA 45
migraine 44
cardiomyopathy 43
glucose intolerance 42
nocturia 39
DM1 36
ischemia 36
tonsillar hypertrophy 35
pulmonary edema 35
chronic pain 35
renal failure 34
chronic disease 32
parasomnia 32
REM sleep behavior disorder 32
right heart failure 31
fatty liver 31
Sleep disturbance 30
hypogonadism 30
vascular disease 29
anemia 29
pneumonia 28
bruxism 28
cold 27
neuropathy 27
more...
Symptom
sleepiness 1061
snoring 981
insomnia 365
hypercapnia 246
fatigue 217
collapse 186
anesthesia 168
pain 161
overweight 143
CSR 143
hypersomnia 129
headache 127
dyspnea 100
seizures 98
eds 97
weakness 71
cough 53
ENT 53
hypotonia 51
discomfort 40
discomfort 40
hypocapnia 38
enuresis 36
stridor 36
distraction 35
myoclonus 33
respiratory distress 33
ataxia 27
analgesia 26
angina 24
abnormal breathing 23
tremor 18
syncope 18
agitation 18
hyperoxia 15
Poor sleep 15
lethargy 14
arthralgia 14
dysarthria 12
nasal congestion 12
cyanosis 12
shortness of breath 11
nocturnal polyuria 11
vomiting 11
nausea 11
wheezing 10
dystonia 10
regurgitation 10
cerebellar ataxia 9
bedwetting 9
Periodic breathing 8
spasm 8
constipation 8
chronic cough 8
breath holding 8
heartburn 8
chest pain 8
hypothermia 7
exhaustion 7
sneezing 7
tachypnea 7
memory loss 7
dizziness 7
orofacial pain 6
sore throat 6
polyuria 6
tinnitus 6
spasticity 6
back pain 6
exertional dyspnea 6
hepatosplenomegaly 6
hunger 5
abdominal pain 5
bradypnea 5
rhinorrhea 5
leg edema 5
stigma 5
vertigo 4
Morning headache 4
nasal discharge 4
more...
Drug
Cardiovasc 57
ENT 54
Modafinil 18
Asthma 18
caffeine 15
Growth hormone 12
Diurnal 12
CSF 11
Monit 11
Dial 10
ROC 9
Growth hormone 9
Theophylline 8
Spectrum 7
Dermatol 7
Check 7
DM1 7
MAP 7
Nephron 7
ROS 5
Nephron 4
Orlistat 4
nitroglycerin 4
Propofol 4
Allergen 4
vitamin E 3
Spectrum 3
Pegvisomant 3
Android 3
Atenolol 2
Xanthium 2
CTX 2
DEX 2
ABC 2
Omalizumab 2
Ethanol 2
Mirtazapine 2
Aldurazyme 2
Idursulfase 2
IL-2 2
Albumin 2
Liraglutide 2
Aldurazyme 2
Zonisamide 2
Angiotensin II 2
Atropine 2
Leaf 2
Xyrem 2
DDAVP 1
Glutathione 1
MINO 1
niacin 1
Clopidogrel 1
Domperidone 1
DPA 1
Triad 1
Codeine 1
Agomelatine 1
ETA 1
Equipoise 1
Anafranil 1
Dakar 1
Galsulfase 1
Methyldopa 1
Anafranil 1
Ketorolac tromethamine 1
NLF 1
Frontal 1
ADM 1
Phenytoin 1
Clonidine 1
Serum albumin 1
Horizon 1
Ramelteon 1
MDS 1
Phentolamine 1
Tilade 1
Gabapentin 1
Nitric Oxide 1
Ipratropium bromide 1
more...
Enzyme
renin 64
carbonic anhydrase 11
ACE 10
mitogen-activated protein kinase 9
superoxide dismutase 8
protein kinase 8
ERK 8
acetylcholinesterase 7
NADPH oxidase 7
alanine aminotransferase 7
protein kinase C 7
NADPH oxidase 7
phosphodiesterase 6
aspartate aminotransferase 6
NO synthase 6
CAD 5
calcineurin 5
CAD 5
ATPase 5
MAP 5
CAD 5
catalase 5
thrombin 3
cathepsin K 3
alpha-L-iduronidase 3
cholinesterase 3
choline acetyltransferase 3
glutathione peroxidase 3
lactate dehydrogenase 3
GSK 3
iduronate-2-sulfatase 3
caspase-3 3
tyrosine hydroxylase 3
DAT 2
AST 2
alkaline phosphatase 2
CPT 2
creatine kinase 2
lipase 2
tissue plasminogen activator 2
FFT 2
focal adhesion kinase 2
chymase 2
CPT 2
luciferase 2
alcohol dehydrogenase 2
PAT 2
ADH 2
peroxidase 2
CPT 2
heme oxygenase 2
AMP-activated protein kinase 2
CD10 2
adenylate cyclase 2
succinate dehydrogenase 2
phospholipase C 2
SPT 2
SPT 2
lysozyme 1
myosin ATPase 1
proteasome 1
NAO 1
cystathionine beta-synthase 1
alpha-glucosidase 1
cytochrome oxidase 1
paraoxonase 1
prolyl hydroxylase 1
proteinase K 1
IMP dehydrogenase 1
tryptophan hydroxylase 1
caspase-7 1
glycerol-3-phosphate dehydrogenase 1
O-GlcNAc transferase 1
caspase-8 1
cystathionine gamma-lyase 1
ACAT 1
caspase-9 1
AMPK 1
PKG 1
HSD 1
more...
Compound
oxygen 982
Clin 723
Dec 635
CO2 206
glucose 142
Cardiol 122
water 112
sodium 50
nitric oxide 46
His 46
aldosterone 41
calcium 33
DNA 31
ethanol 27
Insulin 23
creatinine 22
potassium 21
iron 20
salt 20
noradrenaline 19
Optimal 19
TNF 18
5-HT 15
caffeine 15
MIT 13
homocysteine 13
acetate 13
MIT 13
Acetazolamide 12
PAP 12
PAP 12
Testosterone 12
PAP 12
PAP 12
Testosterone 12
phosphate 10
Thyroid 10
nitrogen 10
DSM 10
Dial 10
Theophylline 10
glutamate 9
arginine 9
6-12 9
ATP 9
silver 8
GABA 7
Melatonin 7
tryptophan 7
H2S 7
8-OHdG 7
tryptophan 7
tryptophan 7
tryptophan 7
hydrogen 7
GABA 7
MAP 6
SO2 6
2-nonenal 6
Nicotine 6
ASA 6
Angiotensin II 6
urea 6
acrylamide 5
cAMP 5
A 42 5
sulfate 5
cysteine 5
SDS 4
ANS 4
PAS 4
Propofol 4
zinc 4
barium 4
Cholesterol 4
DBP 4
dUTP 4
DDD 4
Androgen 4
DBP 4
more...