Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0037315 (sleep apnea)
 8,000 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 550
REM 250
CPAP 250
insulin 234
CO2 123
renin 64
growth hormone 59
MRI 56
leptin 55
ENT 53
COPD 46
CSA 45
She 43
Mol 38
Mal 36
Pol 35
hemoglobin 31
natriuretic peptide 31
SAS 30
cytokine 30
IL-6 29
orexin 28
PSG 28
CSR 27
C-reactive protein 25
STOP 24
interleukin-6 22
cage 22
erythropoietin 20
tumor necrosis factor 19
lymphoid 19
SIDS 19
angiotensin II 19
TNF-alpha 18
TNF 18
ANOVA 18
adiponectin 18
reserved 17
chronic renal failure 15
Leptin 15
somatostatin 15
endothelin-1 14
atrial natriuretic peptide 13
ICD 12
thyroid hormone 12
PAP 12
Men 12
gut 12
HDL 11
CSF 11
FEV 11
CRP 11
resistin 10
dream 10
nitric oxide synthase 10
carbonic anhydrase 10
Growth hormone 9
X-linked 9
MPS II 9
HLA 9
ATP 9
vascular endothelial growth factor 9
vasopressin 8
ET-1 8
Gen 8
P300 8
IGF-I 8
albumin 8
SNA 8
TCS 8
DM1 8
ghrelin 8
GABA 7
endoplasmic reticulum 7
NMDA receptor 7
collagen 7
IL-8 7
axonal 7
prolactin 7
plasminogen activator inhibitor 6
CA1 6
calcium channel 6
fibrinogen 6
phosphodiesterase 6
IGF-1 6
superoxide dismutase 6
rhodanese 6
alanine aminotransferase 6
asymmetrical 6
c-fos 5
Ang II 5
MAP 5
ATPase 5
nodal 5
plasminogen activator inhibitor-1 5
short form 5
Orexin 5
aspartate aminotransferase 5
glucagon 5
epididymal 5
GH receptor 5
mineralocorticoid receptor 5
San 5
PKC 5
inducible nitric oxide synthase 5
JAMA 5
caspase-3 5
substance P 5
glial fibrillary acidic protein 5
human leukocyte antigen 5
ROS 5
CAD 5
SBP 5
APA 4
calcitonin 4
beta-endorphin 4
CD8 4
MNK 4
HTN 4
TLR4 4
DDD 4
insulin-like growth factor-I 4
vascular endothelium 4
SDS 4
AHDC1 4
adipokine 4
tumor necrosis factor alpha 4
ASA 4
DBP 4
Adiponectin 4
Facioscapulohumeral muscular dystrophy 4
angiotensin receptor 4
LTB 4
tyrosine hydroxylase 4
IL-10 4
tau protein 4
erythroid 4
interferon 4
insulin-like growth factor 1 4
ACE 4
OPT 4
neuropeptide Y 4
angiotensin II receptor 4
sex hormone binding globulin 4
arginine vasopressin 4
NMR 4
ankylosing spondylitis 4
acetylcholinesterase 4
ART 4
p38 4
insulin-like growth factor 4
P-selectin 4
PSA 4
thyroid stimulating hormone 3
SPA 3
olfactory 3
alpha-L-iduronidase 3
PCA 3
galactosamine 3
thrombin 3
more...
Disease
sleep apnea 8000
obstructive sleep apnea 1699
hypertension 1067
obesity 1005
sleep disorders 757
diabetes 475
heart failure 443
depression 364
stroke 339
cardiovascular disease 336
narcolepsy 251
sleep disturbances 244
chronic obstructive pulmonary disease 226
type 2 diabetes 189
pulmonary hypertension 177
restless legs syndrome 164
congestive heart failure 156
asthma 155
metabolic syndrome 142
respiratory failure 123
coronary artery disease 114
cognitive impairment 109
cancer 103
epilepsy 100
heart disease 94
atherosclerosis 94
gastroesophageal reflux disease 93
sudden infant death syndrome 92
dementia 87
acromegaly 85
myocardial infarction 77
dyslipidemia 75
renal disease 75
morbid obesity 72
Central sleep apnea 72
myocardial ischemia 71
coronary heart disease 67
Alzheimer's disease 65
osteoarthritis 62
Parkinson's disease 61
lung disease 57
respiratory disease 56
SEM 54
movement disorder 54
hypothyroidism 53
Syndrome 52
tumor 51
hyperlipidemia 51
polycystic ovary syndrome 49
cor pulmonale 49
cataplexy 49
ventricular hypertrophy 48
Down syndrome 47
COPD 46
dysphagia 46
Thorax 46
CSA 45
migraine 44
cardiomyopathy 43
glucose intolerance 42
nocturia 39
DM1 36
ischemia 36
pulmonary edema 35
chronic pain 35
tonsillar hypertrophy 35
renal failure 34
chronic disease 32
REM sleep behavior disorder 32
parasomnia 32
right heart failure 31
fatty liver 31
hypogonadism 30
Sleep disturbance 30
anemia 29
vascular disease 29
pneumonia 28
bruxism 28
neuropathy 27
hallucinations 27
cold 27
essential hypertension 27
rhinitis 26
behavior disorder 26
chronic renal failure 26
multiple sclerosis 26
allergic rhinitis 26
sleepwalking 25
confusion 25
infertility 24
cardiovascular risk factor 24
glaucoma 24
Nose 24
mental illness 23
endometrial stromal sarcoma 23
osteoporosis 23
preeclampsia 23
erectile dysfunction 22
cleft palate 22
fibromyalgia 21
ARF 21
polycythemia 21
dysplasia 21
mental retardation 21
anxiety disorders 21
otitis media 20
major depressive disorder 20
developmental delay 20
parkinsonism 19
aldosteronism 19
rheumatoid arthritis 19
arthritis 19
mental retardation 19
chronic bronchitis 18
hyperglycemia 18
recurrent tonsillitis 18
PAF 18
cystic fibrosis 18
Obesity hypoventilation syndrome 18
amyotrophic lateral sclerosis 18
genetic disorder 18
delirium 17
ADHD 17
idiopathic pulmonary fibrosis 17
scoliosis 17
Thoracic 16
erythrocytosis 16
aggression 16
hydrocephalus 16
hypercholesterolemia 16
psychosis 16
acute myocardial infarction 16
secondary hypertension 16
schizophrenia 16
alcoholic fatty liver 16
interstitial lung disease 16
Upper airway obstruction 15
polio 15
alcoholism 15
liver disease 15
fluid overload 15
cerebral ischemia 15
chronic fatigue syndrome 15
proteinuria 15
sinusitis 14
hyperphagia 14
transient ischemic attack 14
neurological disease 14
Best 14
decubitus 14
incontinence 14
autism 14
pulmonary embolism 14
emphysema 14
craniosynostosis 14
hypoglycemia 14
myopathy 14
mountain sickness 14
sexual dysfunction 14
respiratory acidosis 13
more...
Symptom
sleepiness 1061
snoring 981
insomnia 365
hypercapnia 246
fatigue 217
collapse 186
anesthesia 168
pain 161
CSR 143
overweight 143
hypersomnia 129
headache 127
dyspnea 100
seizures 98
eds 97
weakness 71
cough 53
ENT 53
hypotonia 51
discomfort 40
discomfort 40
hypocapnia 38
stridor 36
enuresis 36
distraction 35
myoclonus 33
respiratory distress 33
ataxia 27
analgesia 26
angina 24
abnormal breathing 23
syncope 18
agitation 18
tremor 18
Poor sleep 15
hyperoxia 15
lethargy 14
arthralgia 14
nasal congestion 12
dysarthria 12
cyanosis 12
shortness of breath 11
vomiting 11
nausea 11
nocturnal polyuria 11
wheezing 10
dystonia 10
regurgitation 10
cerebellar ataxia 9
bedwetting 9
heartburn 8
breath holding 8
chest pain 8
spasm 8
Periodic breathing 8
constipation 8
chronic cough 8
hypothermia 7
exhaustion 7
dizziness 7
memory loss 7
sneezing 7
tachypnea 7
orofacial pain 6
spasticity 6
hepatosplenomegaly 6
polyuria 6
back pain 6
exertional dyspnea 6
sore throat 6
tinnitus 6
hunger 5
stigma 5
rhinorrhea 5
abdominal pain 5
leg edema 5
bradypnea 5
nasal discharge 4
vertigo 4
orthopnea 4
functional recovery 4
Sedation 4
Depressive symptoms 4
asthenia 4
cachexia 4
bradykinesia 4
facial pain 4
nausea and vomiting 4
paresthesia 4
myalgia 4
diarrhea 4
Morning headache 4
skin irritation 4
Hypersomnolence 4
lightheadedness 4
hepatomegaly 4
hoarseness 4
drooling 3
low back pain 3
dry throat 3
apathy 3
forgetfulness 3
neuralgia 3
joint stiffness 3
Wind 3
productive cough 3
respiratory problem 3
acute pain 3
decreased appetite 3
Fluctuation 3
hot flashes 2
Nasal symptoms 2
dysesthesia 2
incoordination 2
dysuria 2
feeling of choking 2
anosmia 2
motor symptom 2
hypertonia 2
personality change 2
numbness 2
ophthalmoplegia 2
neck pain 2
chronic constipation 2
Postoperative pain 2
blackout 2
pallor 2
paresis 2
halitosis 2
body pain 2
Respiratory abnormalities 2
loss of taste 2
Ill 2
situational stress 2
hemoptysis 2
torticollis 1
partial seizure 1
Nocturnal angina 1
hypoproteinemia 1
Visual symptoms 1
catarrh 1
syncopal episodes 1
Welt 1
inanition 1
polydipsia 1
hot flushes 1
Decreased activity 1
lassitude 1
Mouth breathing 1
clubbing 1
thigh pain 1
right upper quadrant pain 1
Hudson 1
otalgia 1
muscle cramps 1
Orthostasis 1
peri-menopausal 1
clonus 1
clumsiness 1
HSA 1
more...
Drug
Cardiovasc 57
ENT 54
Modafinil 18
Asthma 18
caffeine 15
Diurnal 12
Growth hormone 12
CSF 11
Monit 11
Dial 10
ROC 9
Growth hormone 9
Theophylline 8
Spectrum 7
MAP 7
DM1 7
Dermatol 7
Nephron 7
Check 7
ROS 5
Propofol 4
Orlistat 4
Allergen 4
nitroglycerin 4
Nephron 4
Pegvisomant 3
vitamin E 3
Spectrum 3
Android 3
Albumin 2
Atenolol 2
Leaf 2
DEX 2
ABC 2
Omalizumab 2
CTX 2
Xanthium 2
Aldurazyme 2
Liraglutide 2
Mirtazapine 2
Ethanol 2
Atropine 2
Aldurazyme 2
Idursulfase 2
Zonisamide 2
IL-2 2
Angiotensin II 2
Xyrem 2
DDAVP 1
Glutathione 1
MINO 1
niacin 1
Clopidogrel 1
Domperidone 1
DPA 1
Triad 1
Codeine 1
Agomelatine 1
ETA 1
Equipoise 1
Anafranil 1
Dakar 1
Galsulfase 1
Methyldopa 1
Anafranil 1
MOF 1
NLF 1
Frontal 1
ADM 1
Phenytoin 1
Gastro 1
Serum albumin 1
Horizon 1
Rimonabant 1
Diclofenac sodium 1
Ramelteon 1
Nadolol 1
Ketorolac tromethamine 1
ZnO 1
MDS 1
Phentolamine 1
Tilade 1
Gabapentin 1
PNT 1
Clonidine 1
Portal 1
Atrovent 1
Triazolam 1
Norplant 1
Ipratropium bromide 1
IPD 1
Nitric Oxide 1
DDAVP 1
Lovastatin 1
Posture 1
Vitamin A 1
Codeine 1
CCL 1
CTC 1
Exenatide 1
Kenyan 1
Nedocromil sodium 1
TAC 1
ADR 1
Tapentadol 1
Armodafinil 1
DBS 1
Ritalin 1
lysine 1
Glucagon 1
Fraction 1
PTH 1
Singular 1
Remeron 1
Pramipexole 1
Triad 1
Forskolin 1
AVC 1
TAK 1
Camp 1
Ranitidine 1
Pramipexole 1
Fluticasone propionate 1
Digitalis 1
CAM 1
Tryptophane 1
Cetuximab 1
Enzyme
renin 64
carbonic anhydrase 11
ACE 10
mitogen-activated protein kinase 9
superoxide dismutase 8
ERK 8
protein kinase 8
acetylcholinesterase 7
protein kinase C 7
NADPH oxidase 7
NADPH oxidase 7
alanine aminotransferase 7
phosphodiesterase 6
NO synthase 6
aspartate aminotransferase 6
CAD 5
calcineurin 5
ATPase 5
catalase 5
CAD 5
MAP 5
CAD 5
thrombin 3
cathepsin K 3
alpha-L-iduronidase 3
tyrosine hydroxylase 3
iduronate-2-sulfatase 3
glutathione peroxidase 3
GSK 3
choline acetyltransferase 3
caspase-3 3
lactate dehydrogenase 3
cholinesterase 3
DAT 2
AST 2
CPT 2
creatine kinase 2
lipase 2
FFT 2
tissue plasminogen activator 2
alcohol dehydrogenase 2
CD10 2
focal adhesion kinase 2
phospholipase C 2
peroxidase 2
ADH 2
CPT 2
PAT 2
CPT 2
adenylate cyclase 2
heme oxygenase 2
AMP-activated protein kinase 2
luciferase 2
succinate dehydrogenase 2
chymase 2
alkaline phosphatase 2
SPT 2
SPT 2
lysozyme 1
myosin ATPase 1
proteasome 1
NAO 1
cystathionine beta-synthase 1
alpha-glucosidase 1
cytochrome oxidase 1
paraoxonase 1
prolyl hydroxylase 1
proteinase K 1
IMP dehydrogenase 1
tryptophan hydroxylase 1
caspase-7 1
glycerol-3-phosphate dehydrogenase 1
O-GlcNAc transferase 1
caspase-8 1
cystathionine gamma-lyase 1
PDE 1
ACAT 1
caspase-9 1
glycerol-3-phosphate dehydrogenase 1
CDR 1
collagenase 1
beta-lactamase 1
AMPK 1
sulfatase 1
PKG 1
PARP 1
HSD 1
caspase-1 1
GAS 1
phosphatidylinositol 3-kinase 1
p80 1
chondroitinase 1
PDK1 1
TdT 1
ribonuclease 1
xanthine oxidase 1
hypoxanthine-guanine phosphoribosyltransferase 1
glutathione reductase 1
RNase 1
phosphoinositide 3-kinase 1
sialyltransferase 1
paraoxonase 1
caspase-7 1
methylenetetrahydrofolate reductase 1
MIP 1
acetylserotonin O-methyltransferase 1
AMPK 1
sialyltransferase 1
ribonuclease 1
sialyltransferase 1
BIS 1
P-glycoprotein 1
glutathione S-transferase 1
gamma-glutamyl transpeptidase 1
LasR 1
RNase 1
phenylethanolamine N-methyltransferase 1
methylenetetrahydrofolate reductase 1
thromboxane synthase 1
cholesterol acyltransferase 1
ACS 1
Compound
oxygen 982
Clin 723
Dec 635
CO2 206
glucose 142
Cardiol 122
water 112
sodium 50
nitric oxide 46
His 46
aldosterone 41
calcium 33
DNA 31
ethanol 27
Insulin 23
creatinine 22
potassium 21
iron 20
salt 20
Optimal 19
noradrenaline 19
TNF 18
caffeine 15
5-HT 15
MIT 13
MIT 13
homocysteine 13
acetate 13
Acetazolamide 12
PAP 12
PAP 12
PAP 12
PAP 12
Testosterone 12
Testosterone 12
phosphate 10
Dial 10
Thyroid 10
nitrogen 10
DSM 10
Theophylline 10
glutamate 9
arginine 9
ATP 9
6-12 9
silver 8
H2S 7
GABA 7
GABA 7
8-OHdG 7
Melatonin 7
tryptophan 7
tryptophan 7
tryptophan 7
hydrogen 7
tryptophan 7
ASA 6
MAP 6
SO2 6
Angiotensin II 6
Nicotine 6
2-nonenal 6
urea 6
A 42 5
cysteine 5
sulfate 5
acrylamide 5
cAMP 5
DDD 4
dUTP 4
ANS 4
Pac 4
PAS 4
DBP 4
Propofol 4
DBP 4
zinc 4
barium 4
Cholesterol 4
Androgen 4
SDS 4
ANS 4
ADMA 3
ACTH 3
AMP 3
DMD 3
leucine 3
Tempol 3
vitamin D 3
Clonazepam 3
Protriptyline 3
L-DOPA 3
hydroxyindoleacetic acid 3
tyrosine 3
TSH 3
EDS 3
Aminophylline 3
Adrenal 3
bromide 3
GSH 3
MAD 3
Formal 3
acetamide 3
cGMP 3
AIR 3
manganese 3
HCl 3
Lead 3
palmitic acid 3
Vitamin D 3
cobalt 3
Norepinephrine 3
acetamide 3
GSH 3
ACh 3
THP 3
Homocysteine 2
MEP 2
proline 2
Diabetol 2
Panam 2
CAT 2
aluminum 2
CPT 2
PEG 2
CPT 2
CAM 2
carbonate 2
NADPH 2
Trazodone 2
Methylphenidate 2
MEP 2
CPA 2
Baclofen 2
H2S 2
toluene 2
CAT 2
Homocysteine 2
CAT 2
PAG 2
Diabetol 2
Metformin 2
Hearts 2
DEX 2
Dipyridamole 2
Cereb 2
coenzyme Q10 2
Propranolol 2
Clomipramine 2
Adenine 2
HCO 2
Propranolol 2
Sodium 2
piperidine 2
GMP 2
Ile 2
N2O 2
NADPH 2
Ang II 2
CPA 2
more...