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Query: UMLS:C0037315 (sleep apnea)
 8,000 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In this paper, we extracted hand crafted features from the ECG signals and evaluated the performance of different combination of features for sleep apnoea detection. We calculated the ECG derived respiratory (EDR) signal using three methods (QRS area, amplitude demodulation and fast PCA methods) and then calculated the cardiopulmonary coupling (CPC) spectrum using each EDR method. We then extracted features from the CPC spectrums and the time and frequency representations of the heart rate variability (HRV) and EDR signals Then, we compared the performance results of different combinations of the features used for automated sleep apnoea detection. We also applied a temporal optimisation method by averaging the features of every three adjacent epochs. Two classifiers were used to detect sleep apnoea: the extreme learning machine (ELM), and linear discriminant analysis. The features were evaluated on the MIT PhysioNet Apnea-ECG database. Apnoea detection was evaluated with leave-one-record-out cross-validation. The PCA CPC features obtained the highest accuracy of 86.5% and AUC of 0.94 using LDA classifier. The performance results of the combined features (of PCA method) obtained the same results. We conclude that for this study, the CPC features using fast PCA method are our best feature set for sleep apnoea detection.
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PMID:Comparing Different Methods of Hand-crafted HRV, EDR and CPC Features for Sleep Apnoea Detection. 3194 18

Pulse signals are widely used to evaluate the status of the human cardiovascular, respiratory, and circulatory systems. In the process of being collected, the signals are usually interfered by some factors, such as the spike noise and the poor-sensor-contact noise, which have severely affected the accuracy of the subsequent detection models. In recent years, some methods have been applied to processing the above noisy signals, such as dynamic time warping, empirical mode decomposition, autocorrelation, and cross-correlation. Effective as they are, those methods are complex and difficult to implement. It is also found that the noisy signals are tightly related to gross errors. The Chauvenet criterion, one of the gross error discrimination criterions, is highly efficient and widely applicable for being without the complex calculations like decomposition and reconstruction. Therefore, in this study, based on the Chauvenet criterion, a new pulse signal preprocessing method is proposed, in which adaptive thresholds are designed, respectively, to discriminate the abnormal signals caused by spike noise and poor-sensor-contact noise. 81 hours of pulse signals (with a sleep apnea annotated every 30 seconds and 9,720 segments in total) from the MIT-BIH Polysomnographic Database are used in the study, including 35 minutes of poor-sensor-contact noises and 25 minutes of spike noises. The proposed method was used to preprocess the pulse signals, in which 9,684 segments out of a total of 9,720 were correctly discriminated, and the accuracy of the method reached 99.63%. To quantitatively evaluate the noise removal effect, a simulation experiment is conducted to compare the Jaccard Similarity Coefficient (JSC) calculated before and after the noise removal, respectively, and the results show that the preprocessed signal obtains higher JSC, closer to the reference signal, which indicates that the proposed method can effectively improve the signal quality. In order to evaluate the method, three back-propagation (BP) sleep apnea detection models with the same network structure and parameters were established, respectively. Through comparing the recognition rate and the prediction rate of the models, higher rates were obtained by using the proposed method. To prove the efficiency, the comparison experiment between the proposed Chauvenet-based method and a Romanovsky-based method was conducted, and the execution time of the proposed method is much shorter than that of the Romanovsky method. The results suggest that the superiority in execution time of the Chauvenet-based method becomes more significant as the date size increases.
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PMID:A Pulse Signal Preprocessing Method Based on the Chauvenet Criterion. 3208 8

Many works in recent years have been focused on developing a portable and less expensive system for diagnosing patients with obstructive sleep apnea (OSA), instead of using the inconvenient and expensive polysomnography (PSG). This study proposes a sleep apnea detection system based on a one-dimensional (1D) deep convolutional neural network (CNN) model using the single-lead 1D electrocardiogram (ECG) signals. The proposed CNN model consists of 10 identical CNN-based feature extraction layers, a flattened layer, 4 identical classification layers mainly composed of fully connected networks, and a softmax classification layer. Thirty-five released and thirty-five withheld ECG recordings from the MIT PhysioNet Apnea-ECG Database were applied to train the proposed CNN model and validate its accuracy for the detection of the apnea events. The results show that the proposed model achieves 87.9% accuracy, 92.0% specificity, and 81.1% sensitivity for per-minute apnea detection, and 97.1% accuracy, 100% specificity, and 95.7% sensitivity for per-recording classification. The proposed model improves the accuracy of sleep apnea detection in comparison with several feature-engineering-based and feature-learning-based approaches.
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PMID:A Sleep Apnea Detection System Based on a One-Dimensional Deep Convolution Neural Network Model Using Single-Lead Electrocardiogram. 3272 30


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