Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0037315 (sleep apnea)
8,000 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Objective:To assess the clinical significance of nasal nitric oxide(NNO) levels in children with sleep disordered breathing(SDB).Method:Thirty children with SDB and twenty healthy children were enrolled. The NNO levels were measured non-invasively using a NIOX MINO system. SPSS statistics 20.0 software was used to analyze the data. Result:Compared to healthy children,NNO level was significant higher in children with SDB(Z=-2.215,P<0.05) .Correlation analysis showed that SDB children's NNO level was directly correlated with AHI(r=0.429,P<0.05),and it was inversely correlated with nadir SaO2(r=-0.482,P<0.01).But NNO level was not significantly correlated with other polysomnographic parameters. Conclusion:Our data suggested that NNO levels might be useful for evaluating the disease severity in SDB children.
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PMID:[Airway inflammation in sleep disordered breathing children: preliminary results]. 2987 43