Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0037315 (sleep apnea)
 8,000 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A man presenting with sleep apnoea was found to have a haemangioblastoma at the cervico-medullary junction. The associated hydrocephalus and syringomyelia resolved after excision of the tumour. Postoperatively the patient developed transient bilateral glossopharyngeal neuralgia, presumably due to surgical damages to the tractus solitarius. To the best of our knowledge this is the first reported case with transient bilateral glossopharyngeal neuralgia following resection of a haemangioblastoma of the cervico-medullary junction.
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PMID:Bilateral glossopharyngeal neuralgia after excision of a solitary cervico-medullary haemangioblastoma: case report. 156 41

We describe the case of an 8-year-old child who presented with sleep breathing disorders associated with glossopharyngeal neuralgia. Polysomnographic studies showed central sleep apnoea lasting 10 to 18 seconds in an average frequency of 63 times for every hour of sleep. Magnetic resonance imaging (MRI) studies showed a caudal displacement of the cerebellar tonsils down to C3 level, associated with a syringomyelic cavity in the upper cervical cord and an extramedullary cystic collection at C2. Surgical decompression of the cranio-cervical junction completely relieved the apnoea and the glossopharyngeal neuralgia immediately following the procedure. MRI study performed one month later showed the complete disappearance of the syringomyelic cavity. Two years later this child remains asymptomatic. In childhood the association of Chiari type I malformation with sleep apnoea and glossopharyngeal neuralgia has not been previously reported. The successful outcome after surgery suggests a compressive mechanism on the brainstem and on the IX cranial nerve to explain these two clinical features in our patient.
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PMID:Chiari type I malformation, glossopharyngeal neuralgia and central sleep apnoea in a child. 897 98

Dolichoectatic arteries are elongated tortuous aneurysms of intracranial arteries most commonly of vertebrobasilar tree presenting with ischaemic, haemorrhagic, thromboembolic lesions or with cranial nerve compression. The clinical presentation includes tic douloureux, neuralgia, tinnitus, vertigo, motor or sensory deficits, ataxia, dementia, Parkinsonism, hydrocephalus, headache, migraine, aneurysm, neoplasm, stroke/transient ischaemic attacks, leukoencephalopathy, central sleep apnoea and cerebellar dysfunctions. We present a case of recurrent facial nerve palsy secondary to vertebrobasilar dolichoectasia, an interesting and rare condition.
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PMID:Recurrent facial hemiparesis due to dolichoectatic vertebrobasilar artery: an unusual and ignored cause. 2350 76