Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0037315 (
sleep apnea
)
8,000
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The aim of the presented pilot study was to compare urinary excretion of two plasma proteins similar in molecular mass and isoelectric point: albumin and
alpha-1-antitrypsin
(
AAT
) in patients with different forms of arterial hypertension and in healthy subjects. The 24-h urinary excretion of albumin and
AAT
were assessed in 52 patients, 29 with essential hypertension and 23 with secondary hypertension, caused by renovascular hypertension, adrenal phaeochromocytoma and obturative
sleep apnoea
syndrome. The concentrations of albumin and
AAT
were determined by rocket immunodiffusion. An increase of mean albumin and
AAT
urinary excretion was demonstrated, as compared to the control group, both in the patients with essential hypertension and with secondary hypertension. In 93.2% of the healthy subjects no
AAT
presence in urine was detected. No correlation was found between the excretion of albumin and
AAT
with urine.
...
PMID:Comparison of urinary excretion of albumin and alpha-1-antitrypsin in patients with arterial hypertension. 1035 22