Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0037116 (silicosis)
 1,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
HECTD1 protein 13.1
PPP1R13B 12.1
ZC3H4 12.1
RHOXF1 11.5
GK 2 11.1
C4B5 11.1
HECTD1 10.9
LANCL2 10.1
macrophage receptor with collagenous structure 10.1
solute carrier family 9 9.9
syndecan 2 9.8
INT4 9.8
TICAM1 9.4
HLA-DQB 9.4
Cdc42-interacting protein 4 9.4
TAT1 9.3
ITGA8 9.2
GK2 9.2
targeting protein for Xklp2 9.1
SP-10 8.8
Zinc finger E-box-binding homeobox 2 8.8
desmosomal glycoprotein 1 8.7
nephronectin 8.7
ARL13B 8.6
MCPIP1 8.5
Cathepsin H 8.2
SMR 8.2
fibrinogen alpha chain 8.1
SAP3 8.0
cathepsin X 8.0
C4A3 8.0
BHLHE40 7.9
phosphoglucomutase 1 7.8
NFAT3 7.8
leukotriene B4 receptor 7.7
alternatively spliced product 7.7
ALPK1 7.7
CHAD 7.6
VRK1 7.6
BBC3 7.6
acidic mammalian chitinase 7.5
group-specific component 7.5
oviduct-specific glycoprotein 7.5
SERPING1 7.4
NR1H3 7.4
osteopontin, bone sialoprotein 7.4
HSPD1 7.4
TMX 7.3
PTPN2 7.2
FIZZ1 7.2
collagen type I alpha 1 7.2
SLC11A1 7.2
Interleukin-17A 7.2
NALP3 7.1
TBX2 7.1
BAL 7.1
MARCO 7.0
LAMP2 7.0
PARL 7.0
PSAP 7.0
IL-12B 6.9
HOP 6.9
BLT2 6.9
ID1 6.9
CD204 6.9
Mannan-binding lectin 6.8
PIK3C3 6.8
macrophage receptor 6.8
GDP-dissociation inhibitor 6.8
very low density lipoprotein receptor 6.8
DRP 6.7
Decoy receptor 3 6.7
ELK 6.7
desmoglein 3 6.7
GLI2 6.7
manganese-containing superoxide dismutase 6.6
bone morphogenetic protein 7 6.6
retinoic acid receptor beta 6.5
DQ6 6.5
DR11 6.5
more...
Disease
tuberculosis; chest 14.1
Acute silicosis 14.1
Chronic silicosis 14.1
silicosis 14.1
chalicosis 14.1
Type 1 respiratory failure 14.1
silicotuberculosis 13.6
Silicotics 13.5
Eggshell calcification 13.1
stannosis 13.1
Progressive massive fibrosis 12.9
occupational lung disease 12.1
Simple pneumoconiosis 11.9
talcosis 11.7
Chemical pneumonitis 11.5
pneumoconiosis 11.5
Caplan's syndrome 11.4
anthracosilicosis 11.3
pleural disorder 11.3
Oxalate nephropathy 11.1
asbestosis 11.0
Chronic necrotizing pulmonary aspergillosis 11.0
anthracosis 10.5
broncholithiasis 10.3
Thoracic Disease 10.3
occupational disease 9.9
beryllium disease 9.9
Lupus erythematodes 9.9
pleural plaque 9.5
byssinosis 9.4
Respiratory morbidity 9.2
pulmonary granuloma 9.0
pulmonary fibrosis 8.6
honeycomb lung 8.5
JC virus infection 8.1
arteriolitis 8.1
adiaspiromycosis 8.1
hypersensitivity pneumonitis 8.0
Latent tuberculosis 7.9
pleuropericarditis 7.7
MIN 7.6
MIN 7.6
pulmonary alveolar proteinosis 7.6
myofasciitis 7.6
siderosis 7.4
fibrothorax 7.3
collagenosis 7.2
acroosteolysis 7.2
adenocarcinoma of the gallbladder 7.2
idiopathic pulmonary fibrosis 7.1
interstitial lung disease 7.1
Interstitial fibrosis 6.9
lung disease 6.9
infantilism 6.9
circulatory disorder 6.8
chronic bronchitis 6.8
pulmonary tuberculosis 6.8
atypical mycobacterial infection 6.8
Shaver 6.8
small airways disease 6.7
sarcoidosis 6.7
bronchitis 6.6
tuberculous pleurisy 6.6
scleroderma 6.6
sclerodactyly 6.6
Granuloma 6.6
farmer's lung 6.6
PSS 6.6
bronchitis 6.5
Pancoast 6.5
Spontaneous pneumothorax 6.4
cor pulmonale 6.4
fibroelastosis 6.4
bronchogenic carcinoma 6.4
emphysema 6.3
pachymeningitis 6.3
asthmatic bronchitis 6.1
MacLeod 6.0
Raynaud's phenomenon 6.0
sick building syndrome 6.0
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Symptom
abnormal breath sounds 10.5
Chest discomfort 10.1
Respiratory symptoms 7.2
rales 7.1
non-productive cough 7.0
skin irritant 6.5
catarrh 6.5
chest tightness 5.5
chronic cough 5.4
hemoptysis 5.3
clubbing 5.3
Spots 5.3
dyspnea 5.1
personality change 5.0
productive cough 5.0
adenitis 4.9
cough 4.8
limb pain 4.7
forgetfulness 4.7
exertional dyspnea 4.7
wheezing 4.7
shortness of breath 4.1
hypersomnia 4.1
emaciation 4.0
muscle rigidity 4.0
night sweats 3.9
arthralgia 3.9
asthenia 3.7
abdominal discomfort 3.3
neuralgia 3.3
cyanosis 3.2
respiratory distress 3.2
chest pain 3.0
dysuria 2.8
tachypnea 2.8
hoarseness 2.6
apathy 2.1
chills 2.0
hepatosplenomegaly 2.0
ataxia 1.7
ENT 1.7
weakness 1.7
hepatomegaly 1.6
myalgia 1.4
hypercapnia 1.1
fatigue 1.0
tremor 0.9
dizziness 0.9
insomnia 0.7
Ill 0.6
thinning 0.6
back pain 0.5
sleepiness 0.5
stigma 0.4
anorexia 0.3
headache 0.3
hypothermia 0.0
anesthesia -0.1
collapse -0.7
abdominal pain -0.8
pain -1.3
Drug
Stenorol 10.8
Fangji 10.1
Ferric oxide 10.1
Atractylodes rhizome 9.9
Silica 9.6
Pumice 9.2
Flunisolide 8.5
TMX 7.8
Bosutinib 7.5
Talc 7.3
Terlipressin 7.3
Terlipressin 7.3
Silica gel 6.9
SiO2 6.5
Tuberculin 6.5
Kaolin 6.2
MRC 6.2
ID2 5.9
Emodin 5.2
BCG vaccine 5.0
Emodin 4.9
Dasatinib 4.9
CCL 4.8
NBT 4.7
Isoniazid 4.2
TAK 4.1
Prednisone 4.1
Clopidogrel 4.0
Captopril 3.9
BLM 3.7
Leaf 3.7
Gelatin 3.3
Award 3.3
TiO2 3.2
NAG 3.0
ACT 3.0
Paraffin 3.0
Albumin 2.9
niacin 2.2
ROC 2.2
ENT 2.0
ROS 1.9
IFN-gamma 1.9
IL-2 1.8
Mutagen 1.6
Nephron 1.5
EPA 1.3
ascorbate 1.2
DNase I 1.1
vitamin E 1.0
Nephron 1.0
Ethanol 0.8
CTX 0.8
ZnO 0.4
lysine -0.2
Asthma -0.6
Dial -0.8
CSF -0.8
Dermatol -0.9
Monit -1.0
Cardiovasc -3.5
Enzyme
GK2 8.6
collagenase 3 8.1
galactosylhydroxylysyl glucosyltransferase 7.7
BAL 7.1
cathepsin X 6.9
type III procollagen 6.7
proteinase-3 5.7
prolidase 5.1
Hageman factor 5.1
meprin 5.0
arginase 4.6
MCS 4.5
angiotensin-converting enzyme 2 4.1
hexosaminidase 3.9
thioredoxin reductase 3.8
lysyl oxidase 3.8
caspase-1 3.8
chymase 3.7
phosphoglucomutase 3.7
protein phosphatase 2A 3.5
5'-nucleotidase 3.5
lactate dehydrogenase 3.4
MIP 3.4
ceruloplasmin 3.4
alpha-galactosidase 3.4
glycerol-3-phosphate dehydrogenase 3.3
glycerol-3-phosphate dehydrogenase 3.3
prolyl hydroxylase 3.3
PAM 3.2
ACE 3.1
chondroitinase 3.1
neutrophil elastase 3.1
cathepsin B 3.1
MMP 3.0
chondroitinase 3.0
glutathione peroxidase 3.0
PDK1 3.0
superoxide dismutase 2.9
caspase-8 2.9
elastase 2.9
matrix metalloproteinase 2 2.9
peroxiredoxin 2.7
tryptase 2.7
beta-galactosidase 2.6
hyaluronidase 2.5
CPT 2.5
NADPH oxidase 2.3
CPT 2.3
collagenase 2.3
NADPH oxidase 2.2
beta-glucuronidase 2.2
caspase-3 2.1
xanthine oxidase 2.1
catalase 2.0
chitinase 2.0
acid phosphatase 2.0
lysozyme 2.0
CPT 1.9
topoisomerase 1.9
hyaluronidase 1.9
topoisomerase 1.8
adenosine deaminase 1.8
adenosine deaminase 1.7
CPR 1.7
urokinase-type plasminogen activator 1.7
RNase 1.7
peroxidase 1.7
RNase 1.5
ribonuclease 1.4
ribonuclease 1.4
PARP 1.4
mitogen-activated protein kinase 1.4
NOS 1.3
luciferase 1.2
NO synthase 1.1
reverse transcriptase 1.1
succinate dehydrogenase 1.1
cdc2 1.1
alanine aminotransferase 1.0
renin 1.0
more...
Compound
8-hydroxy-5-quinolinesulfonic acid 11.1
Tetrandrine 10.9
Tetrandrine 10.9
Tetrandrine 10.9
Tetrandrine 10.9
Rubiadin 10.8
Janus Green B 9.1
238A 8.8
Flunisolide 8.5
Dioscin 8.5
Dioscin 8.5
Hydroxylysine 8.3
Asbestos 7.5
SiO2 7.3
2-vinylpyridine 7.0
2-vinylpyridine 7.0
2-vinylpyridine 7.0
Vinyl chloride 6.9
methyl palmitate 6.7
BAL 6.6
Ginsenoside Rg1 6.6
ANCA 6.5
4-methylpyridine 6.5
Hydroxyproline 6.3
silicon 6.1
Mannan 6.0
Protect 6.0
Ethambutol 5.9
Oleanolic acid 5.8
Ellagic acid 5.5
Ural 5.4
TGR 5.3
Nicorandil 5.3
5-formyltetrahydrofolate 5.3
Nodular 5.2
Emodin 5.2
Baicalin 5.2
Tanshinone 5.1
Xenon 5.1
Carrageenan 4.9
DBD 4.9
MAK 4.8
Hematoxylin 4.7
TTA 4.6
NBT 4.6
Carvedilol 4.6
ANA 4.6
ANA 4.6
Lea 4.5
cyclohexanol 4.4
cyclohexanol 4.4
Tumor Necrosis Factor 4.3
tungsten 4.3
Proline 4.2
Bordeaux 4.2
Tin 4.2
DPI 4.2
tin 4.2
aluminum 4.1
Azathioprine 4.1
Rifampicin 4.0
Emodin 4.0
DAP 4.0
DAP 4.0
INH 3.9
GPT 3.9
Glibenclamide 3.9
LTD 3.8
XTT 3.8
chromium 3.8
DFO 3.7
Malondialdehyde 3.7
Lip 3.6
Benin 3.5
Prednisone 3.4
Ang II 3.3
Lac 3.3
SPF 3.3
DTA 3.3
PGD2 3.2
more...