Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0037116 (
silicosis
)
1,822
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
collagen
132
Sep
113
Mol
71
cytokine
52
tumor necrosis factor
42
TNF
28
TNF-alpha
22
superoxide dismutase
21
Fas
20
IL-6
19
CD4
19
lactate dehydrogenase
18
fibronectin
17
lipopolysaccharide
16
Mal
15
inducible nitric oxide synthase
15
BAL
15
MRC
14
IL-10
14
Fas ligand
14
catalase
13
SMA
13
IL-4
13
smooth muscle actin
12
SMR
12
p53
12
interleukin-6
12
IL-18
11
rheumatoid factor
11
IgA
11
NLRP3
11
caspase-3
11
albumin
11
HLA
11
vimentin
11
glutathione peroxidase
10
lymphoid
10
IL-1
10
E-cadherin
10
GSH
10
IL-13
9
CD8
9
COPD
9
myeloperoxidase
9
FEV
9
interferon-gamma
9
ash
8
MAPK
8
interferon
8
chemokine
8
IFN-gamma
7
LDH
7
TGF-beta
7
Ang II
7
She
7
angiotensin II
6
ANA
6
IFN
6
IL-8
6
p21
6
rat)
6
ECM
6
p38
6
IL-2
6
caspase-8
6
ATP
6
SOD
6
Pol
6
IgE
5
MCP-1
5
C-reactive protein
5
cyclooxygenase
5
A-I
5
macrophage receptor with collagenous structure
5
PBS
5
PDGF
5
p62
4
collagenase
4
Bcl-2
4
endoplasmic reticulum
4
more...
Disease
silicosis
1822
pneumoconiosis
255
tuberculosis
216
lung cancer
200
pulmonary fibrosis
153
asbestosis
153
cancer
134
lung disease
111
sarcoidosis
82
occupational disease
68
pulmonary tuberculosis
62
PSS
59
chronic obstructive pulmonary disease
53
emphysema
53
occupational lung disease
52
silicotuberculosis
51
asthma
51
idiopathic pulmonary fibrosis
44
rheumatoid arthritis
41
tumor
39
systemic lupus erythematosus
38
interstitial lung disease
37
bronchitis
36
bronchitis
36
chronic bronchitis
33
scleroderma
32
respiratory disease
28
hypertension
28
hypersensitivity pneumonitis
27
Mycobacterium
27
pneumonia
26
mesothelioma
22
diabetes
21
carcinogenesis
20
pneumothorax
20
HIV
20
carcinoma
20
vasculitis
19
respiratory failure
19
glomerulonephritis
18
lymphadenopathy
17
bronchogenic carcinoma
17
beryllium disease
17
autoimmune disease
16
pulmonary hypertension
15
interstitial pneumonia
14
arthritis
14
anthracosis
13
immunodeficiency
12
renal failure
12
cor pulmonale
11
adenocarcinoma
11
renal disease
11
AIDS
11
GSH
10
Raynaud's phenomenon
10
Thorax
10
bronchiectasis
10
depression
10
malignant mesothelioma
10
Thoracic
9
proteinuria
9
byssinosis
9
gout
9
lymphoma
9
squamous cell carcinoma
9
COPD
9
lupus
9
pulmonary alveolar proteinosis
9
siderosis
8
bronchiolitis
8
Moore
8
ash
8
cirrhosis
8
talcosis
8
infectious diseases
8
metastases
7
broncholithiasis
7
atherosclerosis
7
lymphocytosis
7
more...
Symptom
dyspnea
54
cough
39
hemoptysis
14
respiratory distress
10
chest pain
8
weakness
7
wheezing
7
anesthesia
6
arthralgia
6
pain
6
fatigue
6
exertional dyspnea
5
shortness of breath
5
chronic cough
5
rales
5
Respiratory symptoms
4
headache
4
ataxia
3
productive cough
2
asthenia
2
chest tightness
2
clubbing
2
cyanosis
2
tremor
2
non-productive cough
2
chills
1
hypersomnia
1
myalgia
1
insomnia
1
hypothermia
1
muscle rigidity
1
abdominal discomfort
1
hepatosplenomegaly
1
abnormal breath sounds
1
personality change
1
neuralgia
1
hoarseness
1
night sweats
1
apathy
1
thinning
1
adenitis
1
back pain
1
dizziness
1
sleepiness
1
Chest discomfort
1
ENT
1
anorexia
1
catarrh
1
limb pain
1
hypercapnia
1
dysuria
1
emaciation
1
Spots
1
tachypnea
1
skin irritant
1
collapse
1
Ill
1
abdominal pain
1
hepatomegaly
1
forgetfulness
1
stigma
1
Drug
Silica
110
SiO2
31
Leaf
16
MRC
14
Dermatol
8
TiO2
6
IFN-gamma
6
IL-2
6
ROS
4
lysine
3
ascorbate
3
Tuberculin
3
BCG vaccine
2
Albumin
2
Nephron
2
vitamin E
2
Talc
2
ROC
2
Silica gel
2
CCL
2
ENT
2
NBT
2
Captopril
2
Nephron
2
Terlipressin
1
BLM
1
Cardiovasc
1
ACT
1
NAG
1
Asthma
1
Stenorol
1
Dasatinib
1
Clopidogrel
1
Terlipressin
1
Isoniazid
1
Kaolin
1
Pumice
1
Monit
1
niacin
1
Atractylodes rhizome
1
Flunisolide
1
TMX
1
TAK
1
Gelatin
1
Bosutinib
1
Emodin
1
Award
1
Mutagen
1
ZnO
1
CSF
1
ID2
1
Paraffin
1
Fangji
1
Ferric oxide
1
Emodin
1
Prednisone
1
Ethanol
1
DNase I
1
Dial
1
CTX
1
EPA
1
Enzyme
superoxide dismutase
26
lactate dehydrogenase
18
BAL
15
mitogen-activated protein kinase
14
catalase
13
peroxidase
12
glutathione peroxidase
10
caspase-3
9
ACE
9
ERK
8
luciferase
5
caspase-1
5
collagenase
5
lysozyme
5
arginase
5
beta-galactosidase
5
type III procollagen
4
renin
4
reverse transcriptase
4
protein kinase C
4
elastase
4
ceruloplasmin
3
caspase-8
3
focal adhesion kinase
3
NADPH oxidase
3
RNase
3
RNase
3
hexosaminidase
3
ATPase
3
MIP
3
acid phosphatase
3
alanine aminotransferase
3
NADPH oxidase
3
phosphodiesterase
2
NO synthase
2
topoisomerase
2
alkaline phosphatase
2
xanthine oxidase
2
urokinase-type plasminogen activator
2
beta-glucuronidase
2
hyaluronidase
2
thioredoxin reductase
2
MMP
2
neutrophil elastase
2
trypsin
2
5'-nucleotidase
2
protein phosphatase 2A
2
topoisomerase
2
cathepsin B
2
PARP
2
plasmin
1
ribonuclease
1
lipase
1
collagenase 3
1
protein kinase
1
proteinase-3
1
phospholipase A2
1
APC
1
meprin
1
phospholipase C
1
hyaluronidase
1
glycerol-3-phosphate dehydrogenase
1
ribonuclease
1
matrix metalloproteinase 2
1
lysyl oxidase
1
PDK1
1
chitinase
1
glutathione reductase
1
cathepsin X
1
angiotensin-converting enzyme 2
1
phosphoglucomutase
1
aspartate aminotransferase
1
cdc2
1
alpha-galactosidase
1
CPT
1
Hageman factor
1
CPT
1
chymase
1
succinate dehydrogenase
1
prolyl hydroxylase
1
more...
Compound
silicon
177
Dec
129
oxygen
84
SiO2
62
Clin
57
DNA
50
iron
47
water
31
aluminum
28
TNF
28
Tetrandrine
27
Tetrandrine
27
Tetrandrine
27
Tetrandrine
27
hydrogen
20
calcium
17
BAL
15
titanium
15
chromium
14
tin
12
copper
12
phosphate
12
nitric oxide
12
proline
12
Asbestos
11
acetate
11
cobalt
11
nickel
11
GSH
10
ANCA
10
CO2
10
GSH
10
nitrogen
9
tungsten
8
creatinine
8
cysteine
7
sulfate
7
ASA
7
tyrosine
7
zinc
7
sodium
6
ANA
6
ATP
6
ANA
6
H2O2
6
silver
5
MDA
5
Hydroxyproline
5
vinyl
5
potassium
5
DMSO
4
THP
4
alanine
4
barium
4
Ang II
4
Collagen
4
Hematoxylin
4
THP
4
BCG
4
mercury
4
His
4
Asp
4
ADP
4
N-acetylcysteine
4
ADP
4
ADP
4
leucine
4
lysine
4
2-vinylpyridine
3
tryptophan
3
MTT
3
glucose
3
PGE2
3
tryptophan
3
arginine
3
2-vinylpyridine
3
Ascorbic acid
3
manganese
3
INH
3
salt
3
more...