Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0037116 (silicosis)
 1,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collagen 132
Sep 113
Mol 71
cytokine 52
tumor necrosis factor 42
TNF 28
TNF-alpha 22
superoxide dismutase 21
Fas 20
IL-6 19
CD4 19
lactate dehydrogenase 18
fibronectin 17
lipopolysaccharide 16
inducible nitric oxide synthase 15
Mal 15
BAL 15
MRC 14
Fas ligand 14
IL-10 14
IL-4 13
SMA 13
catalase 13
p53 12
SMR 12
interleukin-6 12
smooth muscle actin 12
IL-18 11
albumin 11
vimentin 11
caspase-3 11
NLRP3 11
IgA 11
rheumatoid factor 11
HLA 11
GSH 10
glutathione peroxidase 10
IL-1 10
E-cadherin 10
lymphoid 10
COPD 9
CD8 9
myeloperoxidase 9
interferon-gamma 9
IL-13 9
FEV 9
interferon 8
chemokine 8
MAPK 8
ash 8
LDH 7
TGF-beta 7
Ang II 7
She 7
IFN-gamma 7
p21 6
ANA 6
p38 6
IL-2 6
ATP 6
IFN 6
rat) 6
ECM 6
caspase-8 6
SOD 6
IL-8 6
angiotensin II 6
Pol 6
A-I 5
PDGF 5
cyclooxygenase 5
macrophage receptor with collagenous structure 5
MCP-1 5
IgE 5
PBS 5
C-reactive protein 5
lysozyme 4
catenin 4
AKT 4
MRI 4
THP 4
ADP 4
Bcl-2 4
ROS 4
chronic renal failure 4
ERK 4
CD95 4
PI3K 4
platelet-derived growth factor 4
ras 4
transforming growth factor-beta 1 4
ACE 4
collagenase 4
monocyte chemoattractant protein-1 4
B10 4
p62 4
endoplasmic reticulum 4
RhoA 4
ESI 4
Nrf2 4
NALP3 4
FDG 4
MyD88 4
thymus 4
type I collagen 4
IL-23 4
renin 4
HLA-DR 4
matrix metalloproteinase 3
Interferon-gamma 3
COX-2 3
IL-17 3
Smad2 3
interleukin-10 3
nitric oxide synthase 3
GLI 3
cytochrome 3
peroxidase 3
AII 3
thioredoxin 3
interleukin-4 3
Gen 3
transferrin 3
p65 3
CO2 3
telomeric 3
Cytokine 3
MIP-1alpha 3
calcium channel 3
CRP 3
vascular endothelial growth factor 3
mast cell 3
PMS 3
tyrosine kinase 3
Hua 3
EPA 3
FGF 3
HLA class II 3
AP-1 3
mTOR 3
bradykinin 3
IkappaBalpha 3
acid phosphatase 3
pyrin 3
white cell 3
FasL 3
Smad3 3
Angiotensin-converting enzyme 3
P2X7 3
ceruloplasmin 3
STAT 3
TLR4 3
gem 3
MMP-9 3
monocyte chemotactic protein 3
topoisomerase I 3
nodal 3
vitronectin 3
K-ras 3
transforming growth factor-beta 3
more...
Disease
silicosis 1822
pneumoconiosis 255
tuberculosis 216
lung cancer 200
asbestosis 153
pulmonary fibrosis 153
cancer 134
lung disease 111
sarcoidosis 82
occupational disease 68
pulmonary tuberculosis 62
PSS 59
chronic obstructive pulmonary disease 53
emphysema 53
occupational lung disease 52
silicotuberculosis 51
asthma 51
idiopathic pulmonary fibrosis 44
rheumatoid arthritis 41
tumor 39
systemic lupus erythematosus 38
interstitial lung disease 37
bronchitis 36
bronchitis 36
chronic bronchitis 33
scleroderma 32
respiratory disease 28
hypertension 28
hypersensitivity pneumonitis 27
Mycobacterium 27
pneumonia 26
mesothelioma 22
diabetes 21
pneumothorax 20
carcinogenesis 20
HIV 20
carcinoma 20
respiratory failure 19
vasculitis 19
glomerulonephritis 18
lymphadenopathy 17
beryllium disease 17
bronchogenic carcinoma 17
autoimmune disease 16
pulmonary hypertension 15
interstitial pneumonia 14
arthritis 14
anthracosis 13
renal failure 12
immunodeficiency 12
cor pulmonale 11
renal disease 11
AIDS 11
adenocarcinoma 11
Thorax 10
bronchiectasis 10
GSH 10
depression 10
malignant mesothelioma 10
Raynaud's phenomenon 10
lymphoma 9
COPD 9
byssinosis 9
pulmonary alveolar proteinosis 9
proteinuria 9
Thoracic 9
gout 9
lupus 9
squamous cell carcinoma 9
bronchiolitis 8
siderosis 8
talcosis 8
infectious diseases 8
cirrhosis 8
ash 8
Moore 8
cold 7
metastases 7
atherosclerosis 7
anthracosilicosis 7
lymphocytosis 7
West 7
broncholithiasis 7
lung carcinoma 7
leukemia 6
connective tissue disease 6
amyloidosis 6
gastric cancer 6
heart failure 6
pulmonary edema 6
carcinomatosis 6
dermatomyositis 6
hepatitis 6
IgA nephropathy 6
cystic fibrosis 6
Wegener's granulomatosis 6
chronic disease 5
Chronic silicosis 5
osteoporosis 5
chronic renal failure 5
Langerhans cell histiocytosis 5
Still 5
malnutrition 5
dysphagia 5
pericarditis 5
lupus 5
aspergillosis 5
adult respiratory distress syndrome 4
systemic disease 4
alcoholism 4
fungal infection 4
myocardial ischemia 4
aggression 4
rare disease 4
cardiovascular disease 4
histoplasmosis 4
Caplan's syndrome 4
Hodgkin's disease 4
pleurisy 4
anemia 4
nephritis 3
respiratory infection 3
MIP 3
thrombocytopenia 3
SLE 3
MIN 3
bronchopneumonia 3
bronchopulmonary dysplasia 3
ischemia 3
MIN 3
stroke 3
influenza 3
MAC 3
Fabry 3
skin disease 3
Progressive massive fibrosis 3
sepsis 3
plaque 3
neoplastic transformation 3
pulmonary granuloma 3
eosinophilia 3
Chronic necrotizing pulmonary aspergillosis 3
Poland 3
Cryptococcus neoformans 3
sepsis 3
ICD 3
pleural plaque 3
lymphadenitis 3
Granuloma 2
interstitial nephritis 2
pachymeningitis 2
non-Hodgkin's lymphoma 2
rheumatism 2
SEM 2
substance abuse 2
coccidioidomycosis 2
dysplasia 2
hemosiderosis 2
genetic disorder 2
Churg-Strauss syndrome 2
more...
Symptom
dyspnea 54
cough 39
hemoptysis 14
respiratory distress 10
chest pain 8
weakness 7
wheezing 7
anesthesia 6
arthralgia 6
pain 6
fatigue 6
exertional dyspnea 5
shortness of breath 5
chronic cough 5
rales 5
Respiratory symptoms 4
headache 4
ataxia 3
productive cough 2
asthenia 2
chest tightness 2
clubbing 2
cyanosis 2
tremor 2
non-productive cough 2
chills 1
hypersomnia 1
myalgia 1
insomnia 1
hypothermia 1
muscle rigidity 1
abdominal discomfort 1
hepatosplenomegaly 1
abnormal breath sounds 1
personality change 1
neuralgia 1
hoarseness 1
night sweats 1
apathy 1
thinning 1
adenitis 1
back pain 1
dizziness 1
sleepiness 1
Chest discomfort 1
ENT 1
anorexia 1
catarrh 1
limb pain 1
hypercapnia 1
dysuria 1
emaciation 1
Spots 1
tachypnea 1
skin irritant 1
collapse 1
Ill 1
abdominal pain 1
hepatomegaly 1
forgetfulness 1
stigma 1
Drug
Silica 110
SiO2 31
Leaf 16
MRC 14
Dermatol 8
TiO2 6
IFN-gamma 6
IL-2 6
ROS 4
lysine 3
ascorbate 3
Tuberculin 3
BCG vaccine 2
Albumin 2
Nephron 2
vitamin E 2
Talc 2
ROC 2
Silica gel 2
CCL 2
ENT 2
NBT 2
Captopril 2
Nephron 2
Terlipressin 1
BLM 1
Cardiovasc 1
ACT 1
NAG 1
Asthma 1
Stenorol 1
Dasatinib 1
Clopidogrel 1
Terlipressin 1
Isoniazid 1
Kaolin 1
Pumice 1
Monit 1
niacin 1
Atractylodes rhizome 1
Flunisolide 1
TMX 1
TAK 1
Gelatin 1
Bosutinib 1
Emodin 1
Award 1
Mutagen 1
ZnO 1
CSF 1
ID2 1
Paraffin 1
Fangji 1
Ferric oxide 1
Emodin 1
Prednisone 1
Ethanol 1
DNase I 1
Dial 1
CTX 1
EPA 1
Enzyme
superoxide dismutase 26
lactate dehydrogenase 18
BAL 15
mitogen-activated protein kinase 14
catalase 13
peroxidase 12
glutathione peroxidase 10
caspase-3 9
ACE 9
ERK 8
lysozyme 5
luciferase 5
beta-galactosidase 5
collagenase 5
arginase 5
caspase-1 5
reverse transcriptase 4
elastase 4
protein kinase C 4
type III procollagen 4
renin 4
ceruloplasmin 3
focal adhesion kinase 3
NADPH oxidase 3
RNase 3
MIP 3
RNase 3
ATPase 3
hexosaminidase 3
caspase-8 3
acid phosphatase 3
alanine aminotransferase 3
NADPH oxidase 3
phosphodiesterase 2
NO synthase 2
topoisomerase 2
urokinase-type plasminogen activator 2
hyaluronidase 2
topoisomerase 2
beta-glucuronidase 2
MMP 2
cathepsin B 2
PARP 2
xanthine oxidase 2
alkaline phosphatase 2
thioredoxin reductase 2
trypsin 2
5'-nucleotidase 2
protein phosphatase 2A 2
neutrophil elastase 2
plasmin 1
ribonuclease 1
lipase 1
collagenase 3 1
protein kinase 1
proteinase-3 1
phospholipase A2 1
APC 1
meprin 1
phospholipase C 1
hyaluronidase 1
glycerol-3-phosphate dehydrogenase 1
ribonuclease 1
matrix metalloproteinase 2 1
lysyl oxidase 1
PDK1 1
phosphatidylinositol 3-kinase 1
cathepsin X 1
peroxiredoxin 1
chitinase 1
glutathione reductase 1
chondroitinase 1
cdc2 1
phosphoglucomutase 1
aspartate aminotransferase 1
adenosine deaminase 1
NOS 1
GK2 1
chondroitinase 1
glutathione S-transferase 1
alpha-galactosidase 1
adenosine deaminase 1
CPT 1
prolidase 1
Hageman factor 1
angiotensin-converting enzyme 2 1
CPT 1
chymase 1
succinate dehydrogenase 1
prolyl hydroxylase 1
ACS 1
glycerol-3-phosphate dehydrogenase 1
MEK 1
thrombin 1
CPT 1
galactosylhydroxylysyl glucosyltransferase 1
MCS 1
PAM 1
CPR 1
tryptase 1
tissue plasminogen activator 1
Compound
silicon 177
Dec 129
oxygen 84
SiO2 62
Clin 57
DNA 50
iron 47
water 31
aluminum 28
TNF 28
Tetrandrine 27
Tetrandrine 27
Tetrandrine 27
Tetrandrine 27
hydrogen 20
calcium 17
BAL 15
titanium 15
chromium 14
nitric oxide 12
phosphate 12
proline 12
copper 12
tin 12
acetate 11
cobalt 11
Asbestos 11
nickel 11
ANCA 10
CO2 10
GSH 10
GSH 10
nitrogen 9
creatinine 8
tungsten 8
ASA 7
cysteine 7
zinc 7
sulfate 7
tyrosine 7
H2O2 6
sodium 6
ANA 6
ANA 6
ATP 6
silver 5
MDA 5
Hydroxyproline 5
vinyl 5
potassium 5
THP 4
alanine 4
N-acetylcysteine 4
barium 4
Ang II 4
ADP 4
Hematoxylin 4
His 4
THP 4
ADP 4
DMSO 4
ADP 4
mercury 4
Collagen 4
Asp 4
leucine 4
BCG 4
lysine 4
Ascorbic acid 3
glucose 3
MTT 3
pyrene 3
PGE2 3
benzene 3
arginine 3
manganese 3
2-vinylpyridine 3
tryptophan 3
salt 3
tryptophan 3
2-vinylpyridine 3
tryptophan 3
INH 3
2-vinylpyridine 3
pyridine 3
tryptophan 3
aspartic acid 2
Malondialdehyde 2
NBT 2
serine 2
galactose 2
GPT 2
cadmium 2
hexose 2
Angiotensin II 2
Lead 2
238A 2
Xenon 2
oxalate 2
iodine 2
Proline 2
aspartic acid 2
fluorine 2
selenium 2
aldehyde 2
molybdenum 2
Dioscin 2
nitrate 2
DTPA 2
PEG 2
aspartic acid 2
aspartic acid 2
Cardiol 2
TOF 2
PMA 2
Nodular 2
Rifampicin 2
aldehyde 2
PEG 2
Dioscin 2
PMA 2
nicotinamide 2
PGE 1
DFO 1
DBA 1
cAMP 1
Emodin 1
CPT 1
5-formyltetrahydrofolate 1
5-HT 1
ABA 1
aflatoxin B1 1
SO2 1
MEK 1
PPD 1
ornithine 1
oxalic acid 1
ornithine 1
Ethambutol 1
phosphorus 1
BCNU 1
methyl palmitate 1
oxalic acid 1
ethanol 1
formic acid 1
oxalic acid 1
Nifedipine 1
Tumor Necrosis Factor 1
oxalic acid 1
DEAE 1
Rubiadin 1
Nicorandil 1
CAT 1
DAP 1
prostaglandin E1 1
oxalic acid 1
Janus Green B 1
ornithine 1
cyclohexanol 1
TGR 1
more...