Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0037116 (silicosis)
 1,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of atypical mycobacterial infections are reported. The first caused by Mycobacterium avium in a patient with silicosis, the second by Mycobacterium xenopii in a subject with evidence of extensive post-tuberculosis pulmonary lesions. Both were treated with ofloxacin with good results.
Pneumonol Alergol Pol 1992
PMID:[Ofloxacin in the treatment of pulmonary changes caused by Mycobacterium avium and Mycobacterium xenopii]. 129 Sep 92

The main purpose of our research was to estimate the ventilation and physical efficiency in 6 patients suffering from aluminosis and silicosis. Chest X-ray examinations, statical spirometric investigations and spiroergometric tests (TSE) were performed. Oxygen levels achieved in this group were equal or even higher than medium values achieved by healthy people. Ability to physical effort can be estimated only using TSE.
Pneumonol Alergol Pol 1995
PMID:[Spirometric investigation and spiro-ergometric test in evaluation of exercise tolerance in patients suffering from aluminosis and silicosis]. 862 Jan 69

We present a case of progressive multifocal leukoencephalopathy (PML) diagnosed at autopsy, in which JC virus infection of the central nervous system was confirmed by means of electron microscopy and immunohistochemistry. The patient had been receiving steroid hormones due to suspected sarcoidosis or pneumoconiosis. Diffuse silicosis in lungs and in hilar and mediastinal lymph nodes was diagnosed at autopsy. Intranuclear inclusions, ultrastructurally typical of JC virus were found in some oligodendrocytes in the white matter. However the strongest immunopositive viral deposits were found in the cerebellar cortex, also within Purkinje cells. Numerous apparently apoptotic cells seen in white matter suggest that this mechanism of cell elimination plays an important role in PML pathogenesis and hence anti-apoptotic treatment may alleviate the symptoms and prolong survival.
Pol J Pathol 2000
PMID:Progressive multifocal leukoencephalopathy (PML) in a patient with silicosis treated previously with steroids. A report of a case with JC virus infection confirmed immunohistochemically and by electron microscopy. 1097 34

39 years old man with granulomatous lesions in both lungs caused by occupational contact with glass fibers was described. He has been working as an bricklayer-plasterer for 18 years and was in contact with lime, cement, plaster, asbestos, dust of coal and wood and with glass fibers. For the last two years before admission in 1993 he has had frequent bronchial infections. On admission he was in good general condition, his spirometric examination and blood gases were within normal limits. On chest x-ray disseminated lesions were found. Those lesions were of the round shapes on chest CT. Many sputum cultures for tubercle bacilli were negative. ANA and ANCA were not found in the serum. ACE was within normal limits. No precipitins to environmental antigens were found. Cancer metastases were suspected and lung biopsy during videothoracoscopy was done. Many foreign body type granulomas were found throughout the specimen. The character of the lesions was not typical for tuberculosis, sarcoidosis, extrinsic allergic alveolitis, silicosis or asbestosis. There are some reports concerning the possibility of development of such lesions after the exposition to glass fibers. We suspect that case is an example of such pathology. His occupational exposition was stopped in 1993 and he was observed without treatment. During the 5 years of observation (up till 1998) he was in good health with stable chest x-ray picture and results of respiratory system function.
Pneumonol Alergol Pol 2000
PMID:[Granulomatous lung lesions after occupational exposure to glass fibers]. 1100 67

We report a rare case of silicosis, histologically corresponding to silicoproteinosis and tuberculosis, in a man working consecutively as a miner, blacksmith and founder. A microscopic study revealed deposits in alveoli, in which immunohistochemistry did not reveal surfactant (SP-A), that was present in the alveolar fluid in alveolar lipoproteinosis.
Pol J Pathol 2002
PMID:Silicoproteinosis of the lung in a 49-year-old man. 1247 20

In the development of systemic lupus erythematosus (SLE) genetic predisposition are essential. The role of external factors such as viral infection, exposure to pesticide and silica dust and cigarette smoking are frequently emphasized in the development of this disease. On the basis of the observed case we decided to describe the problem of connection between silicosis and systemic lupus erythematosus (SLE).
Pol Merkur Lekarski 2008 Jan
PMID:[Silicosis and systemic lupus erythematosus--case report]. 1863 45