Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0037116 (
silicosis
)
1,822
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Cytokines are important mediators of the pathogenesis of lung fibrosis. The experimental studies carried out in our laboratory have used a murine model of lung
silicosis
to explore the activity of interleukin-9, -10 and -12. The data presented in this short overview illustrate the pro-fibrotic activity of anti-inflammatory cytokines (IL-10), and the role of type 2 immune polarisation, as illustrated by the paradoxical effect of IL-9 and the activity of IL-12
p40
subunit.
...
PMID:[Recent findings on the role of cytokines in the pathogenesis of interstitial pulmonary fibrosis]. 1250 16