Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0037116 (silicosis)
 1,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Diagnosis of pneumoconiosis was made in 2 dental technicians presenting with interstitial lung disease. The occupational origin of inhaled dust was confirmed by mineralogic analyses, which disclosed mainly large amounts of chromium-cobalt-molybdenum particles originating from Vitallium prostheses, but also showed abrasives (silica and silicon carbide) and asbestos in 1 patient. The presence of Vitallium and its chemical stability in bronchoalveolar lavage and lung several years after cessation of exposure confirm the resistance of this alloy to corrosion by body fluids. This contrasts with the high solubility of cobalt described in cobalt or hard metal disease. We suggest that dental technician's pneumoconiosis is a complex pneumoconiosis distinct from silicosis, asbestosis, or hard metal disease and that Cr-Co-Mo alloys play a role in its pathogenesis.
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PMID:Dental technician's pneumoconiosis. A report of two cases. 394 27

The authors studied respiratory function in workers of wolfram-molybdenum mine where dust contains nearly 75% of silicon dioxide and considerable amounts of metals. The examinees were those with I stage silicosis and with silicosis complicated by chronic obstructive bronchitis. The respiratory disorders appeared most severe in association of the diseases.
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PMID:[Flow volume curve evaluation of respiratory function in wolfram-molybdenum miners]. 1141 20