Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0037116 (silicosis)
 1,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The records of all patients who were examined for silicosis at the Fund of Occupational Diseases between 1972 and 1976 are reviewed. In 3627 cases the mechanographical record was incomplete leaving 40 376 patients in the study. Electrocardiographic signs of chronic cor pulmonale (C.C.P.) were detected in 5.58 per cent. The severity of C.C.P. was evaluated and the prevalence of the different electrocardiographic signs was examined. The presence and severity of C.C.P. was compared to the radiological stage of silicosis, to the pulmonary function, to the duration of professional exposure to the risk of silicosis and to the use of tobacco. The value of the electrocardiographic signs of C.C.P. was evaluated. It is concluded that the mechanographical record obtained in insurance medicine is a valuable tool for statistical analysis of a disease and that C.C.P. is an infrequent and mostly late complication of silicosis.
Acta Cardiol 1978
PMID:Electrocardiographic signs of chronic cor pulmonale in 40 376 patients with silicosis. 15 45

Silicosis is an occupational lung disorder caused by inhalation of silica dust. It not only causes respiratory disorders but also affects other organs. We report an extremely rare case of silicosis complicated by pericarditis in an 83-year-old male. He had been working as a coal miner and was diagnosed with silicosis at the age of 63. Because he had experienced repeated pericardial effusions, he was referred for a surgical pericardial biopsy to elucidate the cause of his repeated pericardial effusion and to perform pericardial fenestration. Thoracoscopic surgery was performed. The pericardium was resected, and a drain was placed in the left thoracic cavity. Histopathological examination revealed the pericardial degeneration due to silicosis, suggesting that pericarditis and pericardial effusion are related to silicosis. The operation was successful, and he experienced no recurrence of pericardial effusion at the 7-month follow-up.
Case Rep Cardiol 2019
PMID:A Rare Case of Pericardial Effusion in a Patient with Silicosis. 3128 77