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Query: UMLS:C0037116 (silicosis)
 1,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Among 4608 evaluated post mortem records (3452 miners with silicosis and 1156 miners without silicosis or nonminers resp.) 501 cases had developed a bronchial carcinoma. 425 of these observed cases showed a bronchial carcinoma together with silicosis, 76 cases were without anthracosilicosis. The occurrence of the bronchial carcinoma in case of anthracosilicosis did not depend on the time of employment in the underground mining industry. Neither was there a correlation between the determined grade of anthracosilicosis and the frequency of bronchial carcinoma. The diagnosis for 2,8% of these combined cases of anthracosilicosis and bronchial carcinoma was silicotic carcinoma of scar tissue. Statistically no signficant differences could be detected between the two groups of bronchial carcinomata with and without silicosis regarding age structure, kind of propagation and histological type of the bronchial carcinoma.
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PMID:[The concurrence of bronchial carcinoma and anthracosilicosis in the lung (concomitantly a contribution to "silicotic carcinoma in scar tissue of the lung")]. 65 56

The article presents medical examination and clinical data on 117 cases of silicosis, anthracosilicosis, electric welder's pneumoconiosis and dust bronchitis. Diagnostic and therapeutic procedures were performed with due account of generally accepted resort treatment recommendations. The data obtained served as a basis for determining the role of different symptoms and results of complimentary medical, including immunologic, techniques, as well as for objective assessment of the effectiveness of resort treatment of occupational diseases.
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PMID:[An objective assessment of the criteria of the efficacy of sanatorium treatment in patients with occupational lung diseases]. 253 9

The paper is concerned with the results of roentgenofunctional investigation of 293 miners, among them there were 63 patients with dust bronchitis and 230 patients with the main types of dust disease (anthracosis, silicosis and anthracosilicosis). Two-stage roentgenopneumopolygraphy (RPPG) with a chess grid and spiral pneumoroentgenography (SPRG) with a spiral grid were employed. Respiratory dysfunction in patients with pneumoconiosis depended on an x-ray and morphological type of fibrosis and stage of disease rather than on its type. The formation of zones of emphysematous inflation in the apical area, in the upper and middle regions of the lungs was revealed, however signs of basal emphysema were ++undetectable. Analysis of RPPG and SPRG findings has shown that unlike pneumoconiosis, dust bronchitis is characterized by earlier development of respiratory dysfunction of more noticeable type, particularly in early signs of disease.
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PMID:[Experience with the roentgenodiagnosis of disturbances of respiratory function in coal miners]. 280 Mar 15

Cohort studies in three American asbestos factories were undertaken to investigate the effect of fibre type and manufacturing process on lung cancer, mesothelioma, and asbestosis. Reports have been published on a chrysotile textile plant in South Carolina and a mainly textile plant in Pennsylvania, which also used amphiboles. In the third plant in Connecticut friction products and packings were made from chrysotile only. In a cohort of 3641 men employed for one month or more, 1938-58, 3513 (96.5%) were traced, 1267 (36%) had died, and death certificates were obtained for 1228 (96.9%). Individual exposures were estimated (in mcpf . years) from impinger measurements. Life table analyses using Connecticut mortality rates gave an SMR for all causes of 108.5 (USA 107.9). The SMR (all causes) for men who had worked for less than a year was 129.9 and for those who had worked for a year or more, 101.2. The equivalent SMRs for respiratory cancer were 167.4 and 136.7 respectively. Excluding men who had worked for less than a year, there was possible evidence of some increase in risk of lung cancer with increasing exposure, supported also by a "log-rank" (case-control) analysis, of the same order as that observed in chrysotile mining and milling. These findings may be compared with chrysotile textile manufacture where the risk of lung cancer was some 50-fold greater. It is suggested that the differences in risk are perhaps related to the higher proportion of submicroscopic fibres in textile manufacture that may result from the traumatic carding , spinning, and weaving processes. No case of mesothelioma was found, consistent with a much lower risk of this tumour with chrysotile than with amphiboles. Twelve deaths (nine in men with very short and low asbestos exposure) were given ICD code 523 (pneumoconiosis); all but two were ascribed to anthracosilicosis or silicosis and none to asbestosis.
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PMID:Dust exposure and mortality in an American chrysotile asbestos friction products plant. 632 94

263 patients with coniotuberculosis of the intrathoracic lymph nodes were compared clinically according to whether they were or not at 0ccupational risk of silicosis. Patients exposed to quartz dust had some special morphological picture of affected lymph nodes: periadenitis, dust caseosis and tubercula in the presence anthracosilicosis sclerosis. Silicotuberculous broncho-adenitis in silicosis patients is characterized by solitary lesions of the lymph nodes, bronchi, rare dissemination to the lungs. Coniotuberculous broncho-adenitis in elderly subjects arises in the result of occupation-unrelated accumulation in the lymph nodes of coal and quartz dust and runs chronically. Unless the disease is controlled early and actively, it may generalize and aggravate with perforation in the bronchi, vessels and esophagus. Profuse hemorrhage, caverns, atelectasis are also possible.
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PMID:[Comparative characteristics of intrathoracic lymph node coniotuberculosis of occupational and non-occupational etiology]. 852 65

In 50 lung cancers (25 small cell lung cancers, 17 squamous cell carcinomas, 8 adenocarcinomas) pulmonary, mediastinal and cervical lymph node-metastases were analyzed. Lymph-node "skipping" was demonstrated in 46% of the investigated tumors. In seven of these cases the lymph nodes were skipped, which showed complete hyalinization as a consequence of preexisting anthracosilicosis. In 5 other tumors additional lymph nodes with preserved structure were skipped by the metastatic process. Fibrosis of lymphatic tissue after tuberculosis or exposure to ionizing radiation were further reasons for lymph-node skipping. The skipping of intact lymph nodes can be explained by anatomically demonstrable intra- and perinodal short circuit connections. Apart from that, preexisting lymph node changes (silicosis, fibrosis) play an important part.
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PMID:[Discontinuous lymph node metastases ("skipping") in malignant lung tumors]. 932 38

The authors revealed differences in pulmonary volumes, bronchial patency of bronchi at various levels, integral time of air transit in individuals having early anthracosilicosis and silicosis signs vs in healthy miners. During stage 1 of anthracosilicosis and silicosis respiratory function progressively deteriorates and demonstrates moderate disorders. When compared to anthracosilicosis ones, patients having polymetallic dust silicosis showed more significant decrease of the studied parameters.
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PMID:[Comparative analysis of respiratory function in miners suffering from anthracosilicosis and silicosis]. 1184 66