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Query: UMLS:C0037090 (Respiratory symptoms)
 467 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Gastroesophageal reflux (GER) is a dysfunction of the distal esophagus causing movement of stomach contents into the esophagus. Patients may develop heartburn, regurgitation, dysphagia, odynophagia, and hemorrhage. Respiratory symptoms occur in 10-60 percent of patients with GER or hiatal hernia. Although there is evidence associating pulmonary symptoms and GER, causality has not been proven. The appropriate use of antireflux therapy or surgery to treat GER may consequently alleviate respiratory symptoms.
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PMID:Gastroesophageal reflux and respiratory symptoms: is there an association? Proposed mechanisms and treatment. 227 31

The aetiologic factors in gastro-oesophageal reflux disease include the free reflux of gastric juice, the composition of refluxed juice, the defensive mechanisms of the oesophagus, which are both mechanical and mucosal, and, sometimes, gastric abnormalities. Symptoms include heartburn, odynophagia, chest pain, dysphagia, regurgitation, and, occasionally, haemorrhage. Respiratory symptoms may occur. Diagnosis is based on determining the pressure and frequency of reflux (for which pH monitoring is preferred), testing for symptoms that may be caused by reflux, and assessing the degree of oesophagitis, for which endoscopy and histology are the only known techniques.
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PMID:Aetiology, pathogenesis, and clinical manifestations of gastro-oesophageal reflux disease. 306 36