Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0037090 (Respiratory symptoms)
467 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It was on 31st December 2019, that a cluster of pneumonia cases was reported to the World Health Organization (WHO) by China. The initial investigations revealed the cases to be due to a previously unknown "never before seen strain of coronavirus". Coronaviruses are a group of viruses, which are normally present among animals such as cows, bats, camels and cats. The disease was officially named COVID-19 by WHO on 11th February 2020. The International Committee on Taxonomy of Viruses named the virus as SARS-CoV-2 due to its resemblance to SARS coronavirus. According to WHO's Situation Report-28 as of 17th February 2020, globally there were 71,429 confirmed cases, which included both laboratories confirmed and clinically diagnosed cases (applicable only to Hubei province of China). Cases are clinically diagnosed based on their signs and symptoms and chest x-rays without laboratory testing. More than 99% of these are in China i.e. 70,635 and 794 are outside China. The cases reported outside of China belong to 25 countries in various regions of WHO: China having the epicenter of the disease bears the greatest brunt, with 1772 deaths. The three deaths outside China have been reported in Philippines, Japan and France. The case fatality rate of COVID-19 ranges between 2-3% A wide spectrum of disease, ranging from mild to severe, has been reported in confirmed cases of COVID-19. Respiratory symptoms, fever, cough, dyspnoea, myalgia, fatigue, breathing difficulties and bilateral lung infiltrates on C.T are common findings. Pakistan so far has not reported any confirmed case of COVID-19. Government is showing its commitment towards the threat of importation. This novel coronavirus, called as a "devil" by Chinese Prime Minister, Xi Ping is really an enigma.
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PMID:Coronavirus (COVID-19): Let's Prevent Not Panic. 3246 75

In March-April 2020, the Corona Virus Disease 19 (COVID-19) pandemic suddenly hit Italian healthcare facilities and in some of them many staff members became infected. In this work 595 health care workers from a public company were tested for Severe acute respiratory syndrome coronavirus 2 (82 positive) and asked to complete a questionnaire on early COVID-19 symptoms. Respiratory symptoms were present in 56.1% of cases. Anosmia and dysgeusia in COVID-19 cases were found to have an odds ratio (OR) = 100.7 (95% Confidence Interval [CI] = 26.5-382.6) and an OR = 51.8 (95%CI 16.6-161.9), respectively. About one in three of the cases (29.3%) never manifested symptoms. Anxiety was reported by 16.6% of COVID-19 cases and depression by 20.3%, with a significant increase in the estimated risk (OR = 4.3; 95%CI = 2.4-7.4 for anxiety, OR = 3.5; 95%CI = 2.0-6.0 for depression). In cases, sleep was a significant moderating factor in the relationship between occupational stress, or organizational justice, and anxiety. The early diagnosis of COVID-19 in health care workers, must consider, in addition to respiratory disorders and fever, anosmia, dysgeusia, exhaustion, myalgias and enteric disorders. The frequency of anxiety and depression disorders in the population examined was not higher than that commonly recorded in the same company during periodic checks in the years preceding the epidemic. In COVID-19 cases there was a significant risk of anxiety, especially in those who had low sleep quality. Mental health support and improvement interventions must mainly concern workers with positive tests and should also tend to improve sleep quality.
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PMID:Symptoms in Health Care Workers during the COVID-19 Epidemic. A Cross-Sectional Survey. 3269 20

BACKGROUND Coronavirus disease 2019 (COVID-19) has been increasing all over the world. During the pandemic, a variety of presentations have been described. Nevertheless, some patients remain asymptomatic. Respiratory symptoms and gastrointestinal symptoms are often reported among these patients. CASE REPORT Here, we report a case with flank pain. Radiological images were significant for bilateral consolidation, which raised a high suspicion of COVID-19. Hence, on further investigation, he was diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. CONCLUSIONS In the time of the COVID-19 pandemic, patients with multiple comorbidities may present atypically. Flank pain, which is not a usual presentation, may raise the suspicion of COVID-19 infection.
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PMID:A 73-Year-Old Man with a History of Hypertension and Ischemic Heart Disease Who Presented with Pain in the Right Flank as a Symptom of COVID-19 Pneumonia. 3269 3

The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), started at the beginning of December 2019, in Wuhan, Hubei, China. Since then, the disease has been spreading quickly all over the world with dramatic consequences for global health. That is the reason why it was declared pandemic since March 11th, 2020. The clinical presentation of SARS-CoV-2 is quite variable. Respiratory symptoms dominate its clinical manifestations, but based on current observations, it can significantly affect the heart as well, thus leading to myocardial injury. Imaging plays a key role in the cardiovascular management of these patients, with the aim of improving their outcomes. This review article provides an overview as to strengths and weaknesses of cardiac magnetic resonance compared with echocardiography in the difficult management of these patients.
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PMID:Cardiac Involvement in COVID-19-Assessment with Echocardiography and Cardiac Magnetic Resonance Imaging. 3283 39

Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), previously named "2019 novel coronavirus" (2019-nCoV) is an emerging disease and a major public health issue. At the moment, little is known, except that its spread is on a steady upward trend. That is the reason why it was declared pandemic since March 11th, 2020. Respiratory symptoms dominate the clinical manifestations of the virus, but in a few patients also other organs are involved, such as their heart. This review article provides an overview of the existing literature regarding imaging of heart injury during COVID-19 acute infection and follow-up.
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PMID:Imaging in COVID-19-related myocardial injury. 3321 Dec 42