Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0036690 (sepsis)
59,461 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 3707
cytokine 3141
lipopolysaccharide 3117
IL-6 1722
LPS 1687
tumor necrosis factor 1620
TNF 1547
Pseudomonas 1500
Mol 1325
IL-10 907
gut 900
C-reactive protein 878
TLR4 824
She 791
TNF-alpha 727
interleukin-6 654
insulin 597
inducible nitric oxide synthase 558
IL-8 545
albumin 544
thrombin 494
myeloperoxidase 431
nitric oxide synthase 430
fibrinogen 395
tumor necrosis factor alpha 386
IL-1 383
hemoglobin 376
interferon 376
granulocyte 370
CD4 349
CD14 340
protein C 338
IFN 337
caspase-3 315
tissue factor 302
chemokine 300
Cytokine 294
p38 290
ATP 289
TLR2 271
prothrombin 267
CSF 258
lymphoid 258
serum albumin 238
glycoprotein 237
superoxide dismutase 233
antithrombin 233
p65 220
MIC 209
CRP 207
MRI 205
collagen 202
chronic renal failure 200
granulocyte colony-stimulating factor 200
interleukin 6 195
CD11b 194
fibronectin 194
MAPK 192
vascular endothelium 186
CD8 185
IFN-gamma 183
high mobility group box 1 181
thromboplastin 181
catalase 179
IgA 177
MyD88 175
HLA 171
Tumor necrosis factor 167
muscle protein 167
thrombomodulin 166
alanine aminotransferase 166
CLP 165
alkaline phosphatase 164
aspartate aminotransferase 163
IL-1 beta 162
vasopressin 159
Bcl-2 158
antithrombin III 158
interferon-gamma 155
IL-2 150
more...
Disease
sepsis 59461
sepsis 52184
pneumonia 3849
cancer 2771
meningitis 2545
bacteremia 1956
infectious diseases 1579
peritonitis 1511
diabetes 1370
disseminated intravascular coagulation 1228
endocarditis 1081
Infection 1080
tumor 1046
ischemia 1041
renal failure 1034
neutropenia 979
bacterial infection 975
Klebsiella 931
thrombocytopenia 903
acute renal failure 845
heart failure 799
respiratory failure 769
adult respiratory distress syndrome 751
urinary tract infection 732
stroke 701
hypertension 695
anemia 678
cirrhosis 595
coagulopathy 591
necrotizing enterocolitis 581
osteomyelitis 565
depression 559
pancreatitis 551
leukemia 518
HIV 513
malnutrition 508
arthritis 507
liver disease 488
encephalopathy 466
renal disease 465
immunodeficiency 458
lymphoma 455
myocardial infarction 441
carcinoma 420
cellulitis 407
acute pancreatitis 407
rheumatoid arthritis 399
AIDS 397
tuberculosis 392
Haemophilus 392
pulmonary edema 391
Infections 390
prematurity 383
abortion 377
acute myeloid leukemia 370
hepatitis 353
rash 340
leukopenia 338
cholangitis 336
gastroenteritis 323
septic arthritis 323
pulmonary embolism 321
cytomegalovirus 314
pyelonephritis 309
systemic lupus erythematosus 306
congestive heart failure 306
Severe sepsis 305
Crohn's disease 304
pulmonary hypertension 300
hypoglycemia 294
fasciitis 294
chronic renal failure 294
obesity 293
atherosclerosis 291
virus infection 285
cholestasis 285
heart disease 282
influenza 282
fungal infection 280
malaria 279
more...
Symptom
respiratory distress 1450
diarrhea 1008
pain 964
anesthesia 644
abdominal pain 505
vomiting 481
hypothermia 314
weakness 307
seizures 306
nausea 223
dyspnea 212
collapse 208
fatigue 175
lethargy 171
headache 163
splenomegaly 159
anorexia 158
oliguria 157
chills 152
cachexia 144
starvation 130
hepatosplenomegaly 122
tachypnea 120
cough 113
nausea and vomiting 112
Ill 108
erythema 106
hepatomegaly 103
acute abdomen 99
analgesia 99
fever of unknown origin 95
discomfort 83
discomfort 82
back pain 78
chest pain 75
exhaustion 67
sore throat 66
cyanosis 62
hemoptysis 60
constipation 59
colic 55
myalgia 54
arthralgia 53
regurgitation 52
hypercapnia 50
hyperoxia 47
hypotonia 44
shortness of breath 44
sleepiness 37
angina 37
flank pain 36
functional recovery 36
syncope 34
pallor 34
rigors 32
paresis 31
epigastric pain 31
low back pain 30
hypoproteinemia 29
acute abdominal pain 29
ataxia 27
flushing 26
ENT 26
polyuria 26
neck pain 25
dysuria 25
microbial colonization 24
hip pain 23
productive cough 22
pelvic pain 22
bone pain 22
dizziness 21
tremor 21
agitation 21
acidity 20
asthenia 19
abdominal discomfort 18
overweight 18
spasticity 18
right upper quadrant pain 17
more...
Drug
ampicillin 529
Cardiovasc 406
CSF 308
Dermatol 260
IFN-gamma 180
IL-2 150
Dial 144
Monit 123
G-CSF 116
lysine 106
Nephron 103
ROS 99
ascorbate 93
CTX 92
ROC 92
IPM 74
CTX 74
CTX 73
MAP 69
Drotrecogin alfa 62
Drotrecogin alfa 62
Nephron 55
Albumin 53
Bifidobacterium 47
MOF 44
Ceftazidime 43
Heme 42
lactose 41
vitamin E 39
NADH 38
ENT 36
Piperacillin 35
IL-1ra 35
Ringer's solution 33
Portal 33
Indomethacin 30
Meropenem 29
Adriamycin 29
Antithrombin III 28
p75 27
AZT 26
Simvastatin 25
SBT 24
TAK 24
Meropenem 23
Rituximab 23
Gel 23
Fluconazole 22
Propofol 21
AMC 21
Colistin 20
Fraction 20
CPR 19
Nitric Oxide 19
nitroglycerin 19
Serum albumin 19
Amoxicillin 19
caffeine 19
TAT 19
Leaf 17
Augmentin 16
CPZ 16
Methylprednisolone 16
Augmentin 16
Taxol 16
Asthma 16
Prednisolone 16
Cimetidine 15
Cimetidine 15
Ulinastatin 15
Growth hormone 14
Growth hormone 14
Ethanol 14
Zinat 14
Tacrolimus 14
MDS 13
Levosimendan 13
DNase I 13
Glutathione 12
CPT-11 12
more...
Enzyme
APC 683
mitogen-activated protein kinase 521
peroxidase 483
thrombin 483
alanine aminotransferase 354
superoxide dismutase 289
NO synthase 263
aspartate aminotransferase 238
caspase-3 226
ERK 201
catalase 200
thromboplastin 197
beta-lactamase 191
protein kinase 170
lactate dehydrogenase 169
alkaline phosphatase 164
elastase 146
focal adhesion kinase 141
caspase-1 139
proteasome 137
protein kinase C 123
NOS 118
creatine kinase 112
luciferase 108
NADPH oxidase 102
MIP 101
plasmin 97
NADPH oxidase 94
neutrophil elastase 93
renin 88
phospholipase A2 86
tissue plasminogen activator 85
kallikrein 84
AMP-activated protein kinase 77
ATPase 74
lysozyme 74
glutathione peroxidase 70
AST 69
reverse transcriptase 67
MAP 66
phosphodiesterase 63
urokinase-type plasminogen activator 61
neuraminidase 57
heme oxygenase 57
ACS 57
trypsin 56
phospholipase C 55
ACE 55
IKK 52
lipase 51
collagenase 48
xanthine oxidase 48
guanylate cyclase 47
caspase-11 46
complex I 46
caspase-11 46
PARP 43
phosphatidylinositol 3-kinase 42
RNA polymerase 41
AMPK 38
calcineurin 38
BMT 38
caspase-8 37
AMPK 35
pyruvate dehydrogenase 34
DNase 33
MEK 33
acetylcholinesterase 32
CD10 31
caspase-9 30
transcriptase 30
succinate dehydrogenase 29
cytochrome oxidase 28
asparaginase 28
gamma-glutamyl transpeptidase 27
lipoxygenase 27
GSK 27
phosphoinositide 3-kinase 26
cathepsin G 24
RNase 24
more...
Compound
Clin 5036
Dec 3931
oxygen 2108
TNF 1547
DNA 1269
nitric oxide 1194
glucose 1013
creatinine 950
water 903
sodium 640
calcium 627
nitrogen 582
urea 480
arginine 438
iron 433
His 371
phosphate 336
Cardiol 322
ATP 289
CO2 254
glutamine 247
tyrosine 227
galactose 223
sulfate 221
MIC 209
leucine 204
nitrate 199
acetate 195
potassium 184
hydrogen 173
alanine 172
Phe 171
zinc 164
serine 158
DIC 151
lysine 146
Dial 144
cysteine 137
THP 137
THP 137
ethanol 132
Methicillin 132
Parenteral 123
silver 120
prostacyclin 116
GSH 113
GSH 113
Vancomycin 109
iodine 107
cAMP 107
Optimal 104
salt 94
CTX 92
noradrenaline 89
TOF 88
PGE2 85
methionine 85
ADP 85
PEG 83
Insulin 82
ammonia 80
NADP 78
vitamin D 78
Lactate 75
cGMP 74
N-acetylcysteine 74
glutamate 72
barium 71
Ile 71
ACTH 71
ADP 70
GPT 70
SDS 69
Penicillin 69
tryptophan 68
tryptophan 68
MAP 68
ADP 67
threonine 66
tryptophan 66
more...