Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0036690 (
sepsis
)
59,461
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
3707
cytokine
3141
lipopolysaccharide
3117
IL-6
1722
LPS
1687
tumor necrosis factor
1620
TNF
1547
Pseudomonas
1500
Mol
1325
IL-10
907
gut
900
C-reactive protein
878
TLR4
824
She
791
TNF-alpha
727
interleukin-6
654
insulin
597
inducible nitric oxide synthase
558
IL-8
545
albumin
544
thrombin
494
myeloperoxidase
431
nitric oxide synthase
430
fibrinogen
395
tumor necrosis factor alpha
386
IL-1
383
hemoglobin
376
interferon
376
granulocyte
370
CD4
349
CD14
340
protein C
338
IFN
337
caspase-3
315
tissue factor
302
chemokine
300
Cytokine
294
p38
290
ATP
289
TLR2
271
prothrombin
267
CSF
258
lymphoid
258
serum albumin
238
glycoprotein
237
superoxide dismutase
233
antithrombin
233
p65
220
MIC
209
CRP
207
MRI
205
collagen
202
chronic renal failure
200
granulocyte colony-stimulating factor
200
interleukin 6
195
CD11b
194
fibronectin
194
MAPK
192
vascular endothelium
186
CD8
185
IFN-gamma
183
high mobility group box 1
181
thromboplastin
181
catalase
179
IgA
177
MyD88
175
HLA
171
Tumor necrosis factor
167
muscle protein
167
thrombomodulin
166
alanine aminotransferase
166
CLP
165
alkaline phosphatase
164
aspartate aminotransferase
163
IL-1 beta
162
vasopressin
159
Bcl-2
158
antithrombin III
158
interferon-gamma
155
IL-2
150
more...
Disease
sepsis
59461
sepsis
52184
pneumonia
3849
cancer
2771
meningitis
2545
bacteremia
1956
infectious diseases
1579
peritonitis
1511
diabetes
1370
disseminated intravascular coagulation
1228
endocarditis
1081
Infection
1080
tumor
1046
ischemia
1041
renal failure
1034
neutropenia
979
bacterial infection
975
Klebsiella
931
thrombocytopenia
903
acute renal failure
845
heart failure
799
respiratory failure
769
adult respiratory distress syndrome
751
urinary tract infection
732
stroke
701
hypertension
695
anemia
678
cirrhosis
595
coagulopathy
591
necrotizing enterocolitis
581
osteomyelitis
565
depression
559
pancreatitis
551
leukemia
518
HIV
513
malnutrition
508
arthritis
507
liver disease
488
encephalopathy
466
renal disease
465
immunodeficiency
458
lymphoma
455
myocardial infarction
441
carcinoma
420
cellulitis
407
acute pancreatitis
407
rheumatoid arthritis
399
AIDS
397
tuberculosis
392
Haemophilus
392
pulmonary edema
391
Infections
390
prematurity
383
abortion
377
acute myeloid leukemia
370
hepatitis
353
rash
340
leukopenia
338
cholangitis
336
gastroenteritis
323
septic arthritis
323
pulmonary embolism
321
cytomegalovirus
314
pyelonephritis
309
systemic lupus erythematosus
306
congestive heart failure
306
Severe sepsis
305
Crohn's disease
304
pulmonary hypertension
300
hypoglycemia
294
fasciitis
294
chronic renal failure
294
obesity
293
atherosclerosis
291
virus infection
285
cholestasis
285
heart disease
282
influenza
282
fungal infection
280
malaria
279
more...
Symptom
respiratory distress
1450
diarrhea
1008
pain
964
anesthesia
644
abdominal pain
505
vomiting
481
hypothermia
314
weakness
307
seizures
306
nausea
223
dyspnea
212
collapse
208
fatigue
175
lethargy
171
headache
163
splenomegaly
159
anorexia
158
oliguria
157
chills
152
cachexia
144
starvation
130
hepatosplenomegaly
122
tachypnea
120
cough
113
nausea and vomiting
112
Ill
108
erythema
106
hepatomegaly
103
acute abdomen
99
analgesia
99
fever of unknown origin
95
discomfort
83
discomfort
82
back pain
78
chest pain
75
exhaustion
67
sore throat
66
cyanosis
62
hemoptysis
60
constipation
59
colic
55
myalgia
54
arthralgia
53
regurgitation
52
hypercapnia
50
hyperoxia
47
hypotonia
44
shortness of breath
44
sleepiness
37
angina
37
flank pain
36
functional recovery
36
syncope
34
pallor
34
rigors
32
paresis
31
epigastric pain
31
low back pain
30
hypoproteinemia
29
acute abdominal pain
29
ataxia
27
flushing
26
ENT
26
polyuria
26
neck pain
25
dysuria
25
microbial colonization
24
hip pain
23
productive cough
22
pelvic pain
22
bone pain
22
dizziness
21
tremor
21
agitation
21
acidity
20
asthenia
19
abdominal discomfort
18
overweight
18
spasticity
18
right upper quadrant pain
17
more...
Drug
ampicillin
529
Cardiovasc
406
CSF
308
Dermatol
260
IFN-gamma
180
IL-2
150
Dial
144
Monit
123
G-CSF
116
lysine
106
Nephron
103
ROS
99
ascorbate
93
CTX
92
ROC
92
IPM
74
CTX
74
CTX
73
MAP
69
Drotrecogin alfa
62
Drotrecogin alfa
62
Nephron
55
Albumin
53
Bifidobacterium
47
MOF
44
Ceftazidime
43
Heme
42
lactose
41
vitamin E
39
NADH
38
ENT
36
Piperacillin
35
IL-1ra
35
Ringer's solution
33
Portal
33
Indomethacin
30
Meropenem
29
Adriamycin
29
Antithrombin III
28
p75
27
AZT
26
Simvastatin
25
SBT
24
TAK
24
Meropenem
23
Rituximab
23
Gel
23
Fluconazole
22
Propofol
21
AMC
21
Colistin
20
Fraction
20
CPR
19
Nitric Oxide
19
nitroglycerin
19
Serum albumin
19
Amoxicillin
19
caffeine
19
TAT
19
Leaf
17
Augmentin
16
CPZ
16
Methylprednisolone
16
Augmentin
16
Taxol
16
Asthma
16
Prednisolone
16
Cimetidine
15
Cimetidine
15
Ulinastatin
15
Growth hormone
14
Growth hormone
14
Ethanol
14
Zinat
14
Tacrolimus
14
MDS
13
Levosimendan
13
DNase I
13
Glutathione
12
CPT-11
12
more...
Enzyme
APC
683
mitogen-activated protein kinase
521
peroxidase
483
thrombin
483
alanine aminotransferase
354
superoxide dismutase
289
NO synthase
263
aspartate aminotransferase
238
caspase-3
226
ERK
201
catalase
200
thromboplastin
197
beta-lactamase
191
protein kinase
170
lactate dehydrogenase
169
alkaline phosphatase
164
elastase
146
focal adhesion kinase
141
caspase-1
139
proteasome
137
protein kinase C
123
NOS
118
creatine kinase
112
luciferase
108
NADPH oxidase
102
MIP
101
plasmin
97
NADPH oxidase
94
neutrophil elastase
93
renin
88
phospholipase A2
86
tissue plasminogen activator
85
kallikrein
84
AMP-activated protein kinase
77
ATPase
74
lysozyme
74
glutathione peroxidase
70
AST
69
reverse transcriptase
67
MAP
66
phosphodiesterase
63
urokinase-type plasminogen activator
61
neuraminidase
57
heme oxygenase
57
ACS
57
trypsin
56
phospholipase C
55
ACE
55
IKK
52
lipase
51
collagenase
48
xanthine oxidase
48
guanylate cyclase
47
caspase-11
46
complex I
46
caspase-11
46
PARP
43
phosphatidylinositol 3-kinase
42
RNA polymerase
41
AMPK
38
calcineurin
38
BMT
38
caspase-8
37
AMPK
35
pyruvate dehydrogenase
34
DNase
33
MEK
33
acetylcholinesterase
32
CD10
31
caspase-9
30
transcriptase
30
succinate dehydrogenase
29
cytochrome oxidase
28
asparaginase
28
gamma-glutamyl transpeptidase
27
lipoxygenase
27
GSK
27
phosphoinositide 3-kinase
26
cathepsin G
24
RNase
24
more...
Compound
Clin
5036
Dec
3931
oxygen
2108
TNF
1547
DNA
1269
nitric oxide
1194
glucose
1013
creatinine
950
water
903
sodium
640
calcium
627
nitrogen
582
urea
480
arginine
438
iron
433
His
371
phosphate
336
Cardiol
322
ATP
289
CO2
254
glutamine
247
tyrosine
227
galactose
223
sulfate
221
MIC
209
leucine
204
nitrate
199
acetate
195
potassium
184
hydrogen
173
alanine
172
Phe
171
zinc
164
serine
158
DIC
151
lysine
146
Dial
144
cysteine
137
THP
137
THP
137
ethanol
132
Methicillin
132
Parenteral
123
silver
120
prostacyclin
116
GSH
113
GSH
113
Vancomycin
109
iodine
107
cAMP
107
Optimal
104
salt
94
CTX
92
noradrenaline
89
TOF
88
PGE2
85
methionine
85
ADP
85
PEG
83
Insulin
82
ammonia
80
NADP
78
vitamin D
78
Lactate
75
cGMP
74
N-acetylcysteine
74
glutamate
72
barium
71
Ile
71
ACTH
71
ADP
70
GPT
70
SDS
69
Penicillin
69
tryptophan
68
tryptophan
68
MAP
68
ADP
67
threonine
66
tryptophan
66
more...