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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The case of 19-year old men with iatrogenic esophageal wall perforation is presented. The patient underwent anterior cervical stabilization using plate and screw for fracture of the C4 and C5 vertebra followed by an abscess of prevertebral space with discharging pus and food from the wound. The general condition was poor. Symptoms included: pneumonia, pleuritis with effusion, septicemia with mediastinitis, fever up to 40 and quadriplegia on neurological examination. During surgical procedure the implant loose but was still fixed into the esophagus causing a large defect in the posterior wall of the hypopharynx and cervical part of esophagus was found. The patient undergone three step surgery with wide drainage of prevertebral abscess, removing of osteosynthetic plate removal and formation of pedicle flap with sterno-cleido-mastoideus muscule. The finnal fourth procedure with using of pediculed infrahyoid flap gave an excellent result. During 160 days hospitalization the pus culture showed growth of the 11 bacterials species (like Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis) and 2 species of fungus. He was treated 13 types of antybiotics. This special case we present because of live threatening complication (mediastinitis) and complicated clinical course as well as because of unique technique of the defect closure, i.e. the infrahyoid flap occurred to be successful.
Otolaryngol Pol 2005
PMID:[Wide esophageal wall rupture as iatrogenic complication of anterior cervical spine surgery]. 1652 58

An incidence of sepsis, septic shock, systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) is still actual clinical problem. Inducing factors and clinical pictures are similar to recently reported data from comparable populations in North America, Europe and Australia. The most important complication of severe sepsis is organ dysfunction observed in over 30% of sepsis patients hospitalized in intensive care unit. Applied intensive therapy including new generations of antibiotics gives an increase in clinical recovery. However, a hospital mortality of sepsis patients is over 30%.
Pol Merkur Lekarski 2006 Feb
PMID:[Sepsis--actual clinical problem]. 1670 53

Descending necrotic mediastinitis is a serious illness which, among others, follows acute bacterial infections located in a cervical area. One of the most frequent causes of this illness, not connected with surgical interventions, is a peritonsillar and peridental abscess. The process originally placed in the peritonsillar area spreads along the cervical fascia engulfs mediastinum. Inflammatory process of the mediastinum considerably worsens the prognosis and obligates to decisive surgical (mediastinum drainage) and pharmacological (antibiotic therapy) treatments. The following works presents the course of the illness of a 55-year-old man who was diagnosed with severe sepsis in the course of the peritonsillar abscess. After surgical provision of the abscess (incision) the patient was qualified for the therapy with activated protein C (Xigris, Lilly). The patient condition initially improved, however, after 8 days a descending necrotic mediastinitis with ambilateral pleural abscess was diagnosed. The administration of the treatment within 48 days of hospitalization (antibiotic therapy, thoracotomy, flow drainage of the mediastinum, tracheotomy, respirotherapy) brought about the effect of complete recovery.
Otolaryngol Pol 2006
PMID:[Severe sepsis as a complication of descending necrotizing mediastinitis due to a peritonsillar abscess. A case study]. 1690 40

Each factor infection or non-infection (surgery, burn) can be the cause of inflammatory reaction development and in turn releasing of pro- and antiinflammatory mediators. Excessive or/and uncontrol releasing of these mediators leads to endothelium damage and organ dysfunction. Standard analysis of common infection markers, i.e. peripheral blood leukocytes, C-reactive protein, reaction of Biernacki measurements, do not allow to distinguish infection and noninfection reason of systemic inflammatory response. Procalcitonin is the specific marker for bacterial and fungal infection. Its level is low during local bacterial and virus infection, autoimmunological diseases, but it is increased at the patients with sepsis, severe sepsis. In described case (patient with Wegener's granulomatosis) applying procalcitonin measurement and sensitive and specific microbiological diagnostic by using bronchio-alveolal lavage leads to successful treatment.
Pol Merkur Lekarski 2006 Oct
PMID:[Severe sepsis or clinical view of autoaggressive disease. Wegener's granulomatosis--case report]. 1720 75

Endoscopic sphincterotomy and stone extraction has become method of choice in the treatment of residual lithiasis after cholecystectomy. Then safe endeavour and effective, yet despite many advantages possible complications are. The paper presents a rare case endoscopic sphincterotomy under form of gigantic abscess of extraperitoneal space from consequent sepsis and death of patient.
Pol Merkur Lekarski 2007 May
PMID:[Late complication of endoscopic sphincterotomy]. 1767 84

The Yersinia genus belongs to the Enterobacteriacae family and comprises strains pathogenic for humans, which causes diseases of the gastrointestinal system. The infection can be transmitted with blood and blood components causing sepsis. The paper presents Yersinia enterocolitica complications after transfusion of blood and blood components as well as the frequency of occurrence and preventive measures.
Pol Merkur Lekarski 2007 May
PMID:[Infections of the gastrointestinal system--risk of transmission with blood and blood components]. 1767 6

Hyper IgE syndrome (Job's syndrome) is a rare multiorgan disease characterized by the triad: elevated serum IgE level, recurrent sinopulmonary infections, most often staphylococcal, and cutaneous cold abscesses starting in infancy. We report 21 years old patient with hyper IgE syndrome, diagnosed at age of 6 years on the basis of hyperimmunoglobulinaemia E and recurrent pulmonary and cutaneous infections. Now he was admitted because of pneumonia complicating with pneumatocele, which could not be resolved despite intravenous antibiotics. Surgical intervention was necessary. The postoperative period was complicated by Staphyloccocus aureus sepsis.
Pneumonol Alergol Pol 2007
PMID:[Pneumatocele during long-lasting observation of hyper IgE patient]. 1797 30

The aim of the study was to introduce a case of a 49-year-old woman who had been using an intrauterine contraceptive device for 20 years. The pelvic actynomycosis in her case led to sepsis and consequently to her death. Colonisation Actinomyces israeli in women using IUD may amount up to even 20%, however infections occur very seldom. Following the recommended time of IUD usage, cytology and early start of antibiotic therapy may protect patients against the Actinomyces infection.
Ginekol Pol 2007 Dec
PMID:[Pelvic actynomycosis as the result of a long standing use of an intrauterine device. Case report]. 1841 27

Thrombophlebitis of dura venous sinuses is a rare intracranial complication of otitis media, which may be sometimes accompanied by symptoms or sepsis. Anatomical conditions and early diagnosis of this vascular complication determine the treatment modality. Aim of this study was the assessment of diagnostics and treatment of venous sinuses thrombophlebitis in acute and chronic otitis media considering anatomy and the venous sinuses and status of coagulation system. Otogenic thrombophlebitis may occur in lateral, transverse, upper and lower petrosal sinuses, and rarely in cavernous. In some cases thrombophlebitis proces may expand into brain or emissary mastoid veins. Lateral sinus thrombophlebitis in chronic otitis media usually appears clinically as septic fever, earache, and increasing neurologic signs. In acute otitis media when thrombophlebitis develops the patient complains about headache, high fever and visual acquity. Diagnosis of venous sinus thrombophlebitis is based on clinical signs, radiological imaging (CT scan, MRI), bacteriological examinations and laboratory biochemical tests. Contrast enhanced CT scan shows "delta sign". Septic thrombophlebitis sinus sigmoidei is caused by mixed bacterial flora. Surgical treatment in cases with septic thrombus consists of radical modiffied ear operation and lateral sinus exposure. Thrombectomy and jugular vein ligation is performed when sepsis or thrombus is present. Mastoidectomy and tympanic cavity drainage is performed in cases with lateral sinus thrombosis in acute mastoiditis. Intravenous antibiotics therapy should be continued for 2 weeks. Anticoagulants should be given taking into consideration parameters of coagulation system and the type of thrombus. Treatment results of venous sinuses thrombophlebitis are good if they are not accompanied by other intracranial complications.
Otolaryngol Pol 2007
PMID:[Thrombophlebitis of venous sinuses in otitis media]. 1855 16

Supplementary transfusions of granulocyte concentrates were known 70 years ago, when a direct relationship between decrease of the number of circulating granulocytes and the risk of sepsis was found. Using concentrates of granulocytes for treatment of severe bacterial and fungal infections in patients with prolonged neutropenia or disturbances of granulocytes function caused by immunosupression treatment is logically justified. Despite numerous clinical trials, the efficacy and safety of the concentrates transfusion still remains controversial. Early attempts were unsuccessful mainly because insufficient number of cells in concentrates. The technical progress enables now to achieve sufficient number of granulocytes for clinical purposes. Preliminary date suggest their clinical effectiveness. Further clinical studies on the role of granulocyte transfusions in the treatment of severe sepsis in patients with neutropenia or disturbances of granulocyte function caused by immunosupresion are needed.
Pol Merkur Lekarski 2008 Apr
PMID:[Clinical application of granulocyte concentrates in neutropenia caused by immunosupressive treatment]. 1863 71


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