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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Authors wanted to draw attention to possibility of dangerous postoperative complications when the clinical manifestation of reactivation Herpes simplex virus infection develops during the postoperative period. We report a case of parapharyngeal phlegmon following tonsillectomy in a previously healthy 18-year old woman. On postoperative day six signs of Herpes simplex virus infection were presented in our patient. Hypoimmunity causing reactivation of virus led to evolution of septicemia and extended parapharyngeal phlegmon. Management involved parapharyngeal space drainage, broad spectrum antibiotics and gammaglobulin coverage. Treatment was successful. The patient was discharged in good condition in the fourth week of her admission.
Otolaryngol Pol 2004
PMID:[Parapharyngeal phlegmon as a complication after tonsillectomy]. 1531 20

The concentration measurement of the acute phase proteins in blood serum has been applied in differential diagnosis of inflammatory arthritis since a long time. However, it appeared that the qualitative changes such as the presence of different glycoforms of the acute phase protein that was a glycoprotein, enabled to differentiate acute inflammatory conditions including the chronic ones, and to determine the dynamics of inflammatory process. This phenomenon is defined as a main heterogeneity, whereas the determination of the proportions of particular glycoforms is known as glycosylation profile. The changes of this profile are well known in the course of acute inflammatory conditions such as: bacterial sepsis, skin burns complicated with bacterial infections or acute pancreatitis. Considerably less observations concern the chronic conditions as: rheumatoid arthritis, systemic lupus erythematosus and degenerative joint disease. The examination encompassed 25 patients with rheumatoid arthritis, 21 with systemic lupus erythematosus, 19 with reactive arthritis and 21 patients with degenerative joint disease whose diagnosis was established on the basis of international diagnostic criteria. In all these patient the changes of C-reactive protein (CRP), acid glycoprotein (AGP) as well as glycosylation profile of the AGP were evaluated. For this purpose the electrophoresis method of two affinity directions with concanavalin A was applied, whereas the concentration of particular acute phase protein was determined by Laurell's immunoelectrophoresis method. The variants of glycoprotein resulted from electrophoresis were calculated with aid of planimetric method, and the results were presented as a coefficient of glycosylation. The characteristic patterns of glycosylation profile in the course of systemic lupus erythematosus, rheumatoid arthritis and reactive arthritis may be useful in differential diagnosis of the above mentioned diseases.
Pol Merkur Lekarski 2004 Oct
PMID:[Analysis of the acid glycoprotein heterogeneity in patients with arthritis]. 1569 Jun 99

The authors present the case of bilateral internal jugular vein thrombosis, which was diagnosed in a patient after combined therapy (surgery and radiotherapy) because of laryngeal carcinoma. Thrombosis is the frequent complication and the second largest death cause from neoplasms. In review of the literature the cases of bilateral internal jugular vein thrombosis are uncommon. Jugular vein thrombosis has previously been reported in association with deep head and neck infections, sepsis, central vein catherization and the neck injuries. Because of that the presented case of internal jugular vein thrombosis seems to be interesting.
Otolaryngol Pol 2004
PMID:[Bilateral internal jugular vein thrombosis following treatment of laryngeal carcinoma--a case report]. 1573 46

Severe infections caused by Neisseria meningitidis, clinically appearing as meningitis or sepsis, are constantly noted in developed countries, including Poland. Because of rapid clinical course and mortality rate they continue to pose a serious clinical problem. Most cases are sporadic ones, caused by the contact with a healthy carrier of N. meningitidis. Familial and group outbreaks are rare, being responsible for about 1% of cases. However, in family members of patients with meningococcal infection the risk of developing the disease during the following week is about one hundred times higher than in the general population and they should receive an antibiotic prophylaxis. We describe a familial outbreak of meningococcal meningitis with typical clinical features, which appeared in two members of a family during the same day, with a case of acute pharyngitis most likely of the same etiology in the third person, a child. In that instance, practically simultaneous appearance of consecutive cases gave no time for prophylaxis. However, suspicion of meningococcal disease in the first patient contributed to the prompt hospitalization and diagnostics and proper treatment in the two following cases.
Pol Merkur Lekarski 2004 Nov
PMID:[Meningococcal meningitis--familial outbreak]. 1575 42

Abdominal aortic aneurysm surgery (AAA) is associated with perturbations of immune response and decreased immunity to infection, followed by high risk of organ and systemic complications development, including sepsis. The postoperative mortality in patients with AAA comes up to 10-12% and determines us to look for factors that may influence the immune response and are important for uneventful postoperative course. IL-12 is a potent immunoregulatory cytokine, that regulates cellular and humoral immunity. The aim of this study was to determine the IL-12 serum level in patients with AAA and its relation to ischaemia and reperfusion during aortic surgery. The study comprised 17 patients undergoing AAA repair and 10 patients of control group. Peripheral blood samples were taken before surgery (T0), before unclamping of aorta (T1), 90 minutes after unclamping (T2) and 24 h after surgery (T3). The IL-12 serum concentrations were measured with high sensitivity ELISA technique. IL-12 serum concentration was significantly higher in patients with AAA than in control group. During surgery a slight elevation after ischaemia (T1) and great depletion after reperfusion (T2) were observed. We found a significant correlation between IL-12 level at T2 and the length of surgery. The serum level of IL-12 is higher in AAA patients than in healthy men. Ischaemia and reperfusion during AAA repair results in an increase followed by decrease of cytokine serum level. There was not relationship between IL-12 level and its changes and postoperative course of AAA patients.
Pol Arch Med Wewn 2004 Oct
PMID:[Serum concentration of interleukin-12 (IL-12) in patients undergoing abdominal aortic aneurysm repair--preliminary report]. 1577 29

A case of Group B Streptococcus sepsis is reported in a male newborn with a renal vascular hypertension. An abdominal Doppler examination revealed aortic thrombosis extending from renal to the common iliac arteries. Prolonged broad spectrum antibiotic therapy and fibrinolytic treatment combined with surgical thrombectomy were used, at last obtaining improvement of general patient condition. The infant's hypertension resolved and reperfusion of the right kidney and urine output resumed. Ultrasound examination at 4th month showed presence of collateral circulation to arteries providing right lower limb. Patient's long-term out come is still under control of Outpatient Department of Vascular Surgery.
Ginekol Pol 2005 Jan
PMID:[Abdominal aortic-iliac thrombosis as a complication of newborn's bacterial sepsis]. 1584 68

Intraamniotic infection has been recognized as a major etiologic factor for preterm delivery. Several groups have proposed that amniocentesis be used to identify the patient at risk for infectious morbidity. The number of techniques have been studied for rapid identification of bacterial colonization of amniotic cavity. Diagnostic index value of Gram stain, white blood cell count, glucose level and LDH (lactate dehydrogenase) activity for prediction of positive amniotic fluid culture, preterm delivery, clinical infection and neonatal sepsis were shown in the study. Investigators continue attempts to establish a rapid, more useful tests to predict preterm delivery.
Ginekol Pol 2005 Jan
PMID:[Amniotic fluid analysis. Part I: Rapid markers in the prediction of intra-amniotic infection]. 1584 71

One of possible and diagnostically difficult sources of bacterial sepsis may be purulent foci of odontogenic character. We present the case of a pregnant woman, in whom untreated purulent focus within oral cavity led to severe systemic infection. The disease was characterized by persistent hectic fever with accompanying features of intravascular coagulation, anemia and erythema nodosum and no response to antibiotic treatment. It was the second episode of sepsis in this patient in a period of one year, the source of the infectious process not being recognized previously. Dental examination revealed presence of the apical abscess of the tooth 6-, extraction of which led to spectacular clinical improvement, accompanied by the healing of erythema nodosum. The clinical course and outcome of the disease strongly supports odontogenic etiology, in spite of the lack of full microbiological confirmation. Purulent foci within oral cavity, including apical abscesses, constitute significant clinical problem and must be taken into consideration as a potential source of severe and recurrent systemic infections.
Pol Merkur Lekarski 2005 Mar
PMID:[Severe form of odontogenic sepsis--a case report]. 1599 41

A case of 47-year old woman operated on because of a chronic left ventricular false aneurysm caused by Staphylococcus aureus septicemia and endocarditis 8-years earlier is described. After septicemia was cured, clinical status improved so markedly that the patient refused to undergo recommended operation until onset of heart failure (NYHA III). She was operated on from the median sternotomy with the use of cardiopulmonary bypass. After pericardial adhesions were dissected free, the large left ventricular false aneurysm with severely calcified wall was found. The aneurysm was excised completely and its orifice closed with non-absorbable monofilament 3-0 suture. Postoperative course was complicated by epileptic attack accompanied by loss of consciousness and left hemiplegia on 4th day after surgery. Neurological symptoms regressed within 48 hours and on 12th postoperative day she was discharged from a hospital in a good clinical status.
Pol Merkur Lekarski 2005 Jul
PMID:[Chronic left ventricular pseudoaneurysm caused by Staphylococcus aureus septicemia accompanied by endocarditis]. 1619 30

Necrotizing fasciitis (NF) is a potentially lethal soft tissue infection characterized by cutaneous necrosis, suppurative fasciitis, vascular thrombosis and extreme systemic toxicity. It is a rare entity in the head and neck region, but occur most frequently in patients with diabetes and chronic alcoholism. Mostly involved are immunodeficient patients with banal infections of the upper aerodigestive tract, small traumas, but also after surgical procedures. Necrotizing fasciitis is an infection caused by aerobic or anaerobic microorganisms. A strong complication is a streptococcus-associated-toxic shock-syndrome which should be prevented because it is often associated with letal outcome. Septicemia and systemic toxic effects may lead to death within as short a time as 2 to 4 days. Necrotizing fasciitis is often misdiagnosed or the diagnosis is delayed with a mortality rate of approximately 30-70%. Once identified, treatment consists of antimicrobial therapy and surgical debridement followed at a later date with reconstructive surgery. We present a fatal case of craniofacial necrotizing fasciitis (NF) in a 63-year-old diabetic and chronic alcoholic man and discuss it's pathophysiology, clinical manifestations and the best therapeutic choice for this disease. A review of the literature with the clinical presentations, bacteriology diagnosis and treatment was presented.
Otolaryngol Pol 2005
PMID:[Necrotizing fasciitis of the head and neck]. 1652 46


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