Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nine patients examined by arteriography were shown to have mycotic aneurysms involving the thoracic aorta, subclavian artery, renal artery, middle cerebral artery, hepatic artery, and splenic artery. Patients presented with sepsis, chest pain, mediastinal mass, headache, hypertension, and intraperitoneal bleeding. Etiologic factors included endocarditis, septicemia, drug abuse, and poorly controlled soft-tissue infection. Most mycotic aneurysms were virulent processes with rapid progression and only three of the nine patients (33%) survived. Since mycotic aneurysms may be associated with rapid progression and poor prognosis, early recognition is mandatory.
AJR Am J Roentgenol 1978 Dec
PMID:Protean manifestations of mycotic aneurysms. 10 65

In a 5 year period, eight patients in whom acute acalculous cholecystitis developed during intravenous hyperalimentation are reviewed with emphasis on factors contributing to pathogenesis. Gallbladder distention, biliary stasis, and bile inspissation, thought to be important in the pathogenesis of this disease, are enhanced with the use of hyperalimentation, and this potential complication is being seen with increasing frequency in seriously ill or injured patients who are being fed parenterally. In addition to hyperalimentation, sepsis, hypotension, multiple transfusions (more than 10 units), prolonged fasting, and ventilatory support were frequent common denominators. Typical findings of pain, tenderness, and a mass in the right upper abdominal quadrant are infrequent, and the diagnosis rests on a high index of suspicion and ultrasonography. This syndrome may be preventable by the stimulation of gallbladder emptying with intermittent fat ingestion or parenteral infusion of cholecystokinin.
Am J Surg 1979 Dec
PMID:Acute acalculous cholecystitis: a complication of hyperalimentation. 11 61

An analysis of complications arising from hyperalimentation in 17 septic patients in an ICU is presented. All developed hypophyosphatemia. Hyperglycemia necessitated intravenous insulin in 16 patients. Hypoalbuminemia persisted in all patients despite 134 gm of protein a day. Abnormal liver function and azotemia were common. Catheter complications occurred in three of 90 catheter insertions. Mortality in this population was 70%. Guidelines for the use of Dextrostix for monitoring blood glucose levels and a protocol for hyperalimentation in patients with sepsis are suggested.
South Med J 1979 Dec
PMID:Problems encountered with hyperalimentation in critically ill patients. 11 53

A patient with acute leukemia developed two separate episodes of Bacillus cereus septicemia during one hospitalization. Leukopenia as a consequence of cytotoxic chemotherapy preceded both illnesses. The course of the infections was favorably influenced by the return of adequate numbers of circulating granulocytes and aminoglycoside therapy. Only one other compromised host is known to have recovered from this otherwise fatal disease.
South Med J 1979 Dec
PMID:Recovery from Bacillus cereus sepsis. 11 55

The inhibitory effect of sodium acetate on microorganism growth in protein hydrolysate solutions was studied. Solutions of 5% protein hydrolysate and 5% dextrose in water (seven parts) and 50% dextose in water (three parts) containing 0, 30, 50 and 90 mEq/liter of sodium acetate were inoculated with Staphylococcus aureus, Escherichia coli, Candida albicans and Pseudomonas aeruginosa. The number of colony-forming units in the solutions after inoculation was compared with that after incubation for 24 hours at 37 C. Sodium acetate inhibited growth of S aureus and E coli. Growth of P aeruginosa was inhibited in protein hydrolysate solutions with and without sodium acetate; inhibition could not be attributed solely to sodium acetate and may have been releated to pH of the solutions (4.7 to 5.4). Growth of C albicans was not inhibited by sodium acetate. Sodium acetate reduced growth of some common contaminants of protein hydrolysates. Sodium acetate is known to reduce metabolic acidosis, a reported complication of parenteral nutrient therapy and a possible predisposing factor in C albicans sepsis. Addition of sodium acetate to protein hydrolysate solutions should be considered seriously.
Am J Hosp Pharm 1979 Dec
PMID:Sodium acetate as a preservative in protein hydrolysate solutions. 11 72

300 cases of laparoscopic tubal sterilization using a single entry technique under local anesthesia are described. The routine procedure is described along with figures depicting surgical equipment used. Briefly, the fallopian tubes were cauterized by a 3-burn method and the procedure was performed on an outpatient basis. A 10% failure and complication rate is reported, including 3 cases of wound sepsis, 1 case of vaginal laceration, 2 cases of intraabdominal bleeding, 3 cases of drug allergy, 3 cases of extraperitoneal insufflation, and 1 bowel burn. 1 pregnancy occurred (rate of .5) due to unsatisfactory cautery. 15 failed operations occurred due to inadequate anesthesia, pelvic inflammatory disease, and other technical difficulties. Acceptor characteristics are presented tabularly, and the majority were unmarried; age range was from 23-44 years; and parity ranged up to .12. This procedure used a Wolf 10-mm diameter operating laparoscope attached to fiber optic light.
West Indian Med J 1977 Dec
PMID:Laparoscopic tubal sterilization: a report on 300 cases. 14 37

The authors have studied the results of attempts to restore joint movement in stiff knees after septic non-union of fractures of the femoral shaft or after septic arthritis of the knee by arthrolysis and quadriceps release. Fifteen procedures were done on fourteen patients with severe limitation of movements. The results were gratifying; eight very good and four good. No case was made worse. The technique is described in detail and operative and post-operative complications described. A long-term follow-up study showed that the results tended to improve after several years. The prognosis can be based on the degree of flexion obtained during operation, though free flexion should be distinguished from forced flexion. It is concluded that the procedures used are worthwhile in spite of previous sepsis.
Rev Chir Orthop Reparatrice Appar Mot 1978 Dec
PMID:[Surgical treatment of stiff knee following femoral sepsis and septic arthritis of the knee (author's transl)]. 15 46

An outbreak of staphylococcal sepsis in a burns unit occurred between January 1976 and May 1978. Many patients and members of staff had boils, and a number of patients also developed septicaemia. Most of the boils in the early period of the trial and a large proportion of boils in patients during the later period yielded Staphylococcus aureus resistant to penicillin, tetracycline and erythromycin only (PTE), and were shown to be of phage type 95 in the early period while strains were phage typed. From blood cultures, most strains in the early period were of resistance pattern PTE and phage type 95, but in the later period other resistance patterns were predominant. Strains from burns were usually multiresistant (PTEKNML) and of the phage pattern 29/77, which had been endemic in the Unit, but during the early period of the outbreak there was an increased proportion of strains in burns with the resistance pattern PTE and of phage type 95. Staphylococcal sepsis has for many years been very infrequent in the burns unit. This outbreak seems to have been initiated by a strain of phage type 95 and resistance pattern PTE, but during the course of the outbreak the endemic strain of type 29/77 and some other staphylococci seem to have developed enhanced ability to cause clinical infections, conceivably by transduction from the epidemic strain of phage type 95.
J Hyg (Lond) 1979 Dec
PMID:Staphylococcal sepsis in a burns unit. 15 24

The case of a patient with fulminant Clostridium perfringens septicemia and intravascular hemolysis is presented. The organisms in the blood stream were in sufficient quantity to be detected on a peripheral blood smear, and some were found to be within leukocytes. In vivo spore formation by C. perfringens is thought to be uncommon; however, in this patient probable spore formation by this organism was observed within peripheral blood leukocytes. The peripheral polymorphonuclear leukocytes from this patient were also markedly vacuolated.
Am J Clin Pathol 1977 Dec
PMID:Intraleukocytic spore formation and leukocytic vacuolization during Clostridium perfringens septicemia. 20 81

Of 567 patients receiving renal transplantation at the University of Minnesota between October 1967 and October 1975, 22 developed clinical jaundice. Of these 22, nine died with their initial episode of hepatitis, six died within three months of causes associated with liver malfunction, four developed evidence of chronic hepatic failure and only three totally recovered from their illness. Five had clear evidence of Australia antigen positive hepatitis B, four of cytomegalovirus hepatitis, two of herpes hominis hepatitis, one of varicella zoster hepatitis and three of hepatic failure associated with systemic bacterial and/or fungal sepsis. Two of the 22 patients were thought likely to have cytomegalovirus hepatitis though definite proof was absent and in five patients a clear-cut etiology could not be made. In many of these patients the diagnosis was confounded by the previous presence of HB(s)Ag antigen and the frequent occurrence of a previous or concurrent infection with cytomegalovirus. The role of various drugs including azathioprine, sulfisoxazole, chlorpromazine, acetominophen, etc., could not be established but major roles for these agents in the face of the many viral and bacterial infections present in these patients is doubted. No clear-cut therapy could be established although it appears safe to discontinue azathioprine for longer or shorter periods of time with or without substitution of cyclophosphamide without serious deterioration of renal function. The problem of hepatic failure in transplant patients is still unsolved and will require a prospective study of etiologic agents and sub-clinical hepatic dysfunction in order to establish even the first principles of clinical-pathological correlation.
Ann Surg 1978 Dec
PMID:Jaundice after renal allotransplantation. 21 23


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