Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report the successful removal of a mycotic false aneurysm of the descending thoracic aorta. The aneurysm developed after a sepsis secondary to Canadida albicans. General signs of infection were absent at the time of surgery, although the aortic wall was still infected. A Dacron graft was inserted after resection of the entire aortic wall, and irrigation of the left pleura with amphotericin B was started postoperatively. The patient recovered fully and is in good condition one year after the operation.
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PMID:Mycotic false aneurysm of the descending thoracic aorta due to Candida albicans: successful removal and in situ grafting. 1522 55

A case of 47-year old woman operated on because of a chronic left ventricular false aneurysm caused by Staphylococcus aureus septicemia and endocarditis 8-years earlier is described. After septicemia was cured, clinical status improved so markedly that the patient refused to undergo recommended operation until onset of heart failure (NYHA III). She was operated on from the median sternotomy with the use of cardiopulmonary bypass. After pericardial adhesions were dissected free, the large left ventricular false aneurysm with severely calcified wall was found. The aneurysm was excised completely and its orifice closed with non-absorbable monofilament 3-0 suture. Postoperative course was complicated by epileptic attack accompanied by loss of consciousness and left hemiplegia on 4th day after surgery. Neurological symptoms regressed within 48 hours and on 12th postoperative day she was discharged from a hospital in a good clinical status.
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PMID:[Chronic left ventricular pseudoaneurysm caused by Staphylococcus aureus septicemia accompanied by endocarditis]. 1619 30

We report 2 cases of axillary artery injury secondary to low-energy proximal humeral fractures. In case 1, early diagnosis based on signs of acute ischaemia of the arm enabled early treatment and a favourable outcome. In case 2, there were no signs of ischaemia or neurological deficit, resulting in delayed diagnosis and increased severity of the injury. The patient developed a false aneurysm and sepsis and eventually died. A high index of suspicion is necessary for diagnosing an axillary artery injury. We recommend that all patients with proximal humeral fractures with severe medial displacement of the shaft and a bone spike should routinely undergo Doppler ultrasound scanning to rule out vascular injuries and the presence of a false aneurysm.
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PMID:Axillary artery injury secondary to displaced proximal humeral fractures: a report of two cases. 1872 81

Mycotic false aneurysm caused by local arterial injury from attempted intravenous injections in drug addicts remains a challenging clinical problem. The continued increase in drug abuse has resulted in an increased incidence of this problem, particularly in high-volume urban centres. In the drug-abusing population, mycotic arterial pseudoaneurysms most often occur because of missed venous injection and are typically seen in the groin, axilla, and antecubital fossa. Mycotic aneurysms may lead to life-threatening haemorrhage, limb loss, sepsis, and even death. Any soft-tissue swelling in the vicinity of a major artery in an intravenous drug abuser should be suspected of being a false aneurysm until proven otherwise and should prompt immediate referral to a vascular surgeon for investigation and management. We report a case of rupturing mycotic pseudoaneurysm of the left common femoral artery treated by surgical resection followed by vessel reconstruction with autologous material. Unfortunately, at the time of discharge a sudden leakage from the vein graft anastomosis occurred, with subsequent massive bleeding, and required emergent endovascular covered stenting. To the best of our knowledge, this is the first reported case of femoral artery bleeding in a drug abuser treated by stent graft placement.
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PMID:Emergency stent grafting after unsuccessful surgical repair of a mycotic common femoral artery pseudoaneurysm in a drug abuser. 1893 76

Primary aortoenteric fistula is most commonly caused from erosion of the bowel wall by an abdominal aortic aneurysm. Septic aortitis with pseudoaneurysm formation and finally erosion into the duodenum represents a rare cause that has been described in very few patients in the literature. We present a rare clinical case of Salmonella aortitis and associated infrarenal aortic pseudoaneurysm that evolved into an aortoduodenal fistula. A 51-year-old man was admitted in our hospital with symptoms and signs of sepsis caused by Salmonella bacteremia. Imaging studies revealed an infrarenal aortic pseudoaneurysm. The patient presented hemodynamic instability, and during emergency laparotomy a fistula was found between the third portion of the duodenum and a false aneurysm arising from a nonaneurysmal grossly infected aorta. The affected aortic segment was excised and the intestinal defect was repaired. The aortic stumps were sutured and an axillobifemoral bypass was performed. The patient had an uncomplicated postoperative course.
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PMID:Primary aortoenteric fistula due to septic aortitis. 2047 86

Infection of an abdominal aortic prosthesis with an enteroprosthetic fistula is a very serious, life-threatening complication, leading sometimes to severe functional consequences, the most serious being amputation. Since the symptoms, if there are any, are often rather non-specific, diagnosis is frequently difficult and has always to be based on a whole series of justifications. Early diagnosis is essential and this fistula should be the first possibility considered in a patient with an abdominal aortic prosthesis who is presenting rectorrhagia or melaena (even if only to a slight degree), sepsis and/or abdominal pain. Although rare, the clinical existence of hypertrophic osteoarthropathy may assist diagnosis. A CT scan is the examination of choice, the criteria providing evidence of a fistula being the presence of gaseous images in a periprosthetic fluid collection, thickening and/or retraction of the intestinal walls in contact, the existence of a false aneurysm, and finally, very rarely, extravasation of contrast agent into the intestinal lumen. The differential diagnoses that may mimic a fistula need to be well known, and can include retroperitoneal fibrosis, an infectious aneurysm, inflammatory or infectious aortitis, and above all, a 'simple' prosthesis infection without fistulisation.
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PMID:Aorto-enteric fistulas: a physiopathological approach and computed tomography diagnosis. 2309 21


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