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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Perinatal infections with bacteria belonging to the genus campylobacter are being increasingly recognized. We present a case of early onset neonatal sepsis with Campylobacter jejuni (previously C. Fetus ss. jejuni or Vibrio jejuni). The infant was born prematurely at 31 weeks of gestation and presented with respiratory distress and frequent apnoea from birth. The chest X-ray film demonstrated reticulogranular pattern consistent with hyaline membrane disease. The infant was successfully treated with ampicillin and gentamicin. C. jejuni infection should be considered in the differential diagnosis of early onset sepsis in the neonate and can mimic the radiological picture of hyaline membrane disease.
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PMID:Early onset neonatal sepsis with Campylobacter jejuni: a case report. 202 21

Perinatal infections with Streptococcus pneumoniae although rare, have caused morbidity and mortality in both neonatal and puerperal patients. To determine the incidence of proven pneumococcal sepsis in these patient groups, blood culture records from 1977 to 1989 were reviewed. Of 89 parturient patients with true positive blood cultures, two (2.2%) were positive for the pneumococcus, whereas of 240 infants with positive blood cultures, three (1.25%) grew pneumococcus. The incidence of maternal pneumococcal sepsis was 0.04/1000 live births, and that of the neonates, 0.06/1000, and the overall rate for sepsis in these two groups was 1.7 and 4.7/1000 live births, respectively. In three mother-infant pairs, the identical pneumococcal serotypes, 7, 18, and 23, were isolated from both mother and infant. Birthweights and gestational ages of the infants ranged from 2330 to 3730 gm and 34 to 40 weeks, respectively. Respiratory distress and poor peripheral perfusion were the predominant clinical signs in the infants with sepsis and became apparent from shortly after birth until 5 days of life. Pyrexia, poor general condition, and leukocytosis characterized the mothers with sepsis. All patients survived following antibiotic and supportive care. Our epidemiologic survey confirms the rareness of perinatal pneumococcal infection and the ability of these organisms to cause morbidity in both mothers and infants.
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PMID:Perinatal infections with Streptococcus pneumoniae. 844 88

The predisposition of the newborns to contract infections diseases is dependent upon the limited efficiency of their immune mechanisms. Congenital infections amount to 5.7% in the research material, and the acquired infections 1.15%. The isolation of the microorganism is the basis for treating infections-the profiles of the pathogenic bacterial in flora were subjected to analysis. Im generalised infections Stafphylococcus epidermidis makes 56.6% and E. Coli accounts for 87.5 of the infections of the urinary system. In our research the late sepsis and pneumonia are more frequently the result of the hospital infection (14.2%) in the cases of congenital infections-pneumonia and the infection of the urinary system (72%). Hematologic indicators such as: leucopenia, thormbocytopenia, I/T are distinct infection markers (those were found in 31% of the cases). The CRP protein shows the lowest values in congenital infections, still monitoring its level is useful for assessing the effectiveness of the undertaken antybacterial treatment. The newborns of male sex (58%) more often prone to infection. Pneumonia is the manifestation pertaining to an organ in 70% of congenital infections, the infection of urinary system amounts to 17.1%.
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PMID:[Evaluation of bacteriological research data and laboratory symptoms of infection in the diagnosis of congenital and acquired infections]. 963 74

Perinatal sepsis is one of the most challenging problems encountered in obstetric and intensive care. Sepsis is a clinical diagnosis and a serious pathologic process involving widespread release of inflammatory mediators that may lead to organ injury or rapid deterioration. Normal physiologic maternal adaptations in the intrapartal and early postpartal period may mask the subtle signs of sepsis. Attention to risk factors and early detection may improve outcome of the woman with perinatal sepsis.
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PMID:Perinatal sepsis. 1920 59

Though mineralizing angiopathy is increasingly being recognised as a cause of ischemic stroke in young children, it's cause is not clear. As congenital infections and perinatal infections have been proposed to be associated with mineralizing angiopathy, the authors studied the prevalence of perinatal infections in children with mineralizing angiopathy and compared it with focal cerebral arteriopathy and non-stroke patients. Sixteen children with mineralizing angiopathy, 14 children with focal cerebral arteriopathy and 40 non-stroke patients were enrolled. Detailed parental interview was conducted to look for perinatal infection [Premature rupture of membranes (PROM) and neonatal sepsis]. Perinatal infection (PROM in 8 and documented neonatal sepsis in 2) was seen in 8 patients (68.2%) with mineralizing angiopathy and none of the children with focal cerebral arteriopathy. Only 3 (7.5%) of non-stroke patients had history of PROM. This difference was statistically significant. Perinatal infections could be an important etiological risk factor seen in children with mineralizing angiopathy.
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PMID:Perinatal Infections: An Important Etiological Risk Factor for Mineralizing Angiopathy. 3240 74