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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An increase of the ingestive and digestive capacity of neutrophils to the homologous causative agent and tularemia microbe was revealed by the opsonophagocytic test in Microtus arvalis, albino mice and guinea pigs infected with sublethal Yersinia pseudotuberculosis and Salmonella typhimurium doses. In subsequent tularemia infection some of the animals displayed a reduction of the septicemia intensity, prolongation of the disease and elevation of the susceptibility threshold. Period of manifestation of the inhibitory action on tularemia coincided with that of the increase in phagocytic activity
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PMID:[Change in phagocytic activity toward the agent of tularemia in highly sensitive animals with mixed infections]. 32 67

The clinical symptoms of infections with Y. ent. and pseudotub. are of a different nature. Whether the infection becomes apparent in form of a pseudo-appendicitis, enterocolitis or a typho-septic disease does apparently not only depend on the type of pathogens but also on the children's condition with regard to their resistance. All forms mentioned are observed in case of infections with Yersinia pseudotuberculosis as well as in case of infections with Yersinia pseudotuberculosis as well as in case of infections with Yersinia enterocolitica. However, infections with Yersinia enterocolitica seem to have more frequently a chronic course and to be accompanied by conjunctivitis, arthritis and skin diseases. For the subacute and the chronic forms of the disease, a specific treatment is not necessary in most cases. Severe enterocolitis and septicemia, however, need an antibiotic therapy besides the symptomatic therapy. The best antibiotics for an infection with Yersinia enterocolitica still seem to be the tetracyclines and leucomycine, for an infection with Yersinia pseudotuberculosis also the cephalosporines, ampicilline and carbenicilline.
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PMID:Yersinia enterocolitica and pseudotuberculosis infection in children. 34 79

Yersinia enterocolitica was recovered from the blood of an infant with sepsis and fever but with few gastrointestinal symptoms. The age of this patient was unusual as septicemia owing to this organism has most frequently been seen in adults. Because of the absence of digestive symptoms, it is uncertain what the portal of entry of the organism might have been. Yersinia enterocolitica is not often recognized, either because of difficulties in identification or because it may not be recognized as a human pathogen.
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PMID:Yersinia enterocolitica septicemia. 34 73

The authors discuss the clinical and bacterial characteristics and progressive changes occurring in Yersinia pseudotuberculosis septicemia, basing their observations on one personal case and 30 adult cases reported in the published literature. The roles played by a generally poor condition of the patient and martial overloading are emphasized, and the changes brought about by the introduction of antibiotic therapy evaluated.
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PMID:[Yersinia pseudotuberculosis septicemia in adults (author's transl)]. 38 69

Human infection by Malassez and Vignal's bacillus (Yersinia pseudotuberculosis) can take many clinical aspects, the most frequent of which is mesenteric adenitis with pseudoappendicular syndrome, but occasionally also appearing as a tumor of the right lower abdominal quadrant. In a subsequent stage this mesenteric adenitis is often accompanied by erythema nodosum. There also exist some septicemia-like forms, which have become more and more frequent of late, always appearing on a particular terrain (predisposed persons). These various forms all correspond to contamination via the digestive route. Other, more exceptional modes of contamination may result in much rarer forms, such as ocular or pulmonary forms. Diagnosis is based on: (a) demonstrating the presence of Yersinia pseudotuberculosis, (b) serodiagnosis, (c) a positive intradermal reaction, (d) the characteristic aspect of lymph node lesions. Pseudotuberculosis is extremely frequent in animals. Many species, most of them rodents or birds, can serve as healthy carriers. This is how cats, through their access to this natural "reservoir", get contaminated and thus act as a "conveyor belt" in transmitting the disease to man.
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PMID:Pseudotuberculosis in man: possible epidemiological role of the cats. 40 Sep 44

Yersinia pseudotuberculosis septicemia and postdiarrheal hemolytic-uremia syndrome (HUS) developed in a 15-month-old boy after he ingested unpasteurized goat's milk. The epidemiology of this organism and the disease states caused by it are discussed with the suggestion that an association between it and some cases of the HUS might be found if sought.
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PMID:Yersinia pseudotuberculosis septicemia. 57 75

Infections due to biochemically typical Yersinia enterocolitica usually present as gastroenteritis, mesenteric lymphadenitis, terminal ileitis, and septicemia often with visceral abscesses. In these instances, the isolates have been biochemically typical and of well-established serotypes, namely 0:3 or 0:9 and, in the United States, 0:5 or 0:8. The recovery, recognition, and significance of biochemically and serologically atypical Y. enterocolitica in human infections has proceeded more slowly. From an analysis of the clinical histories of 20 patients infected with 21 such aberrant Y. enterocolitica, it appears that these strains are of restricted pathogenic potential, producing various clinical entities such as localized skin abscesses, conjunctivitis, self-limiting enteritis, and wound and urinary tract infections in hosts with predisposing factors. Epidemiologically, whereas episodic acquisition of atypical strains by hospitalized patients is indicative of nosocomial transmission, in the present series sporadic isolations over a 4-year period, mainly from ambulatory patients, suggest an occult reservoir in the community serviced by The Mount Sinai Hospital. In contrast to typical Y. enterocolitica, which has become well adapted in animal and human hosts, it appears that environmental strains may be in the evolutionary process of becoming adapted to humans.
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PMID:Atypical Yersinia enterocolitica: clinical and epidemiological parameters. 67 Mar 80

Yersinia pseudotuberculosis infections in two bacteriologically confirmed cases are described. A child was found to have mesenteric adenitis and an adult had septicemia. Invariably simulating acute appendicitis, mesenteric adenitis most often occurs in male children and adolescents. Septicemia with this organism usually affects elderly, debilitated patients, who frequently have chronic hepatic disease. The infrequent diagnosis of infection with Yersinia pseudotuberculosis in the United States is probably due to failure to consider it a human pathogen. Currently classified with the Enterobacteriaceae, Yersinia pseudotuberculosis in a non-lactose-fermenting, Gram-negative coccobacillus. It is sensitive to a wide range of antibiotics, including tetracycline and streptomycin, but usually is resistant to ampicillin. Yersinia pseudotuberculosis has a worldwide distribution in wild and domestic mammals and birds. Infections in man may result from direct contact with infected animals or their excreta.
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PMID:Clinical and laboratory aspects of Yersinia pseudotuberculosis infections, with a report of two cases. 77 44

A 58-year-old black man presented with left wrist pain, septicemia, and a chest roentgenographic pattern compatible with septic embolization. Yersinia enterocolitica was grown from joint fluid, blood, and sputum. This unusual constellation of clinical manifestations due to an organism rarely reported as the cause of human disease warrants reporting the case.
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PMID:Nodular pulmonary infiltrates and septic arthritis associated with Yersinia enterocolitica bacteremia. 90 Jun 37

We report a case of Yersinia enterocolitica septicemia with septic arthritis. Gentamicin administration controlled the septicemia but failed to eradicate the organisms in the joint, in spite of a synovial fluid level four times its minimal inhibitory concentration after four days of therapy. Development of azotemia necessitated change of antibiotic therapy to chloramphenicol, which eradicated the infection. While Y enterocolitica infection in the United States is uncommon, it must be added to the list of organisms causing suppurative arthritis and septicemia in susceptible hosts. Septic arthritis must be distinguished from the much more common reactive theumatic polyarthritis associated with Y enterocolimica infection, for which antibiotic therapy is neither needed nor helpful.
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PMID:Yersinia enterocolitica septicemia with septic arthritis. 98 93


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