Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The results of 24 applications of hemosorption procedure in 19 cases of acute leukemia, chronic myeloleukemia, chronic lymphocytic leukemia and multiple myeloma are discussed. Hemosorption in conjunction with infusions of albumin, hemodesum, rheopolyglucinum, saline and glucose solutions may be recommended for severe and extremely severe toxemia. A high efficiency of the procedure application at different stages of leukemia development in cases of toxemia syndrome, toxico-allergic hepatitis and sepsis was observed.
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PMID:[Hemosorption combined with intensive measures in hemoblastoses]. 386 Oct 25

This review describes trends in maternal mortality in Ontario, Canada during 1970 to 1980 inclusive. There has been a significant decline in the total and direct deaths recorded. Anesthetic complications, hemorrhage, obstetric sepsis, and non-obstetric infections are now rare causes of maternal mortality. Toxemia and emboli remain major components of direct obstetric deaths. Collagen vascular disease, cardiac disease, pulmonary emboli, and cerebrovascular accidents are consistently found as causes of indirect maternal deaths.
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PMID:Maternal mortality in Ontario from 1970 to 1980. 404 41

The causes of the high maternal mortality rate (21.6/1000) at the Goroka Base Hospital in Papua New Guinea are reviewed for the 1964-1973 period. This study covers deaths directly due to pregnancy and childbirth and deaths due to other causes occurring in association with pregnancy and childbirth (referred to as associated deaths). The definition of parity in this study is the number of previous pregnancies that have lasted 28 weeks or more. During the 10-year period, 6031 public patients were admitted for confinement and 542 public patients were admitted following delivery elsewhere. For the purpose of deriving the maternal mortality rate (MMR), only direct maternal deaths are considered. The MMR was much higher (97.8) for patients admitted after delivery than for those admitted before delivery. The parity of 74 of the patients who died from direct obstetric causes was recorded: para 0, 52.7%; para 1-4, 40.5%; and para 5 or more, 6.8%. Autopsy confirmed the cause of death in 33 (23.2%) of the 142 maternal deaths. In most patients, sufficient clinical data was available to establish the diagnosis. Sepsis was the predominant cause of death, accounting directly for 44 (38.3%) of the deaths. Obstructed labor accounted for 29 deaths (25.2%) with the uterus intact. Of patients whose parity was recorded, 15 (60%) were primigravida, 8 (32%) were multigravida, and 2 (8%) were multigravida. Of 45 patients admitted to Goroka Base Hospital with the diagnosis of ruptured uterus, the mortality was 28.9%. The incidence of ruptured uterus declined from 1.4% to 0.4% over the 10-year review period. Abortion was the cause of 14 deaths. Criminal interference was admitted in 9 patients and may have occurred in the others. The cause of death of 4 women was toxemia of pregnancy; 2 of these patients were referred from other hospitals, each after treatment for pre-eclampsia. Pulmonary embolism was responsible for 1 death as was extrauterine pregnancy. There were 29 deaths in patients delivered by caesarean section. Additionally, 3 women died after referral following caesarean section at other hospitals. The average duration of hospitalization for patients with peritonitis at or developing after caesarean section was 17.7 days. 27 deaths were associated with pregnancy, and the conditions responsible are listed in a table. Continuing education is necessary to reduce maternal morbidity and mortality. Simple proposals for health education purposes are identified.
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PMID:Maternal mortality at Goroka Base Hospital. 453 53

Murine schistosomiasis mansoni is a more rapidly fatal disease in hosts deprived of their cell-mediated immune capabilities. Analysis of the histopathology of the disease under these circumstances indicates that rather than the hepatic granulomata characteristic of the normal infection, the host develops zones of liquefactive necrosis in the liver and intestinal mucosa. These lesions are associated with severe parenchymal cell destruction. Such hepatic and mucosal damage, with subsequent toxemia and septicemia, is presumed central to the altered course of the disease.
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PMID:Schistosoma mansoni infection in mice depleted of thymus-dependent lymphocytes. II. Pathology and altered pathogenesis. 454 46

Maternal deaths were reviewed at the American University of Beirut Medical Center during an 11 year period, 1971-82. There were 35,058 livebirths and 45 deaths, making a maternal mortality rate of 128/100,000 livebirths. Hemorrhage, sepsis, and toxemia were the main direct causes of obstetric death. The most important indirect causes were cerebrovascular accidents and heart disease. In this, review, an analytic discussion of the direct and indirect causes of maternal death in Lebanon are presented and preventive measures are discussed.
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PMID:Maternal mortality in the American University of Beirut Medical Center (AUBMC) 1971-1982. 615 95

An attenuated tenosynovitis virus vaccine and turkey herpesvirus (HVT) vaccine mixed prior to vaccination were injected subcutaneously into one-day-old chicks. In laboratory and field trials there did not appear to be any interference, because chickens vaccinated with both vaccines were effectively immunized against challenge with virulent Marek's disease virus or tenosynovitis virus when compared with unvaccinated chickens or chickens vaccinated with either HVT or tenosynovitis virus. The combined tenosynovitis and HVT vaccine had essentially the same virus titers when compared to the titers of each vaccine prior to mixing. Also, the HVT viremia levels and the serum neutralization titers of chickens vaccinated with both vaccines were essentially the same as those in chickens vaccinated with a single vaccine. In field trials, chickens vaccinated with the combined vaccines had fewer condemnations for parts and septicemia-toxemia and total condemnations when compared to chickens not vaccinated with tenosynovitis virus. There was less mortality in the majority of the flocks vaccinated with tenosynovitis virus vaccine and HVT when compared to flocks receiving only HVT vaccine.
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PMID:Simultaneous vaccination of one-day-old broiler chickens with tenosynovitis virus and turkey herpesvirus. 631 45

The investigation of sepsis and a number of complications of purulent wounds in 336 patients has shown the expediency to distinguish three stages of the microbial and metabolic toxemia. The third stage of toxemia is found to be the most dangerous (terminal) one. The lethality rate by the data of different scientists can reach 95%. The effective antiseptic method was found to be microvasoplegy, forced antiseptics (antibiotics) with forced diuresis or peritoneal dialysis. The third stage of toxemia with multiple metastases gave poor results after treatment by all the routine methods.
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PMID:[Difficulties in the treatment of wound infection and complications of suppurative wounds]. 715 89

Rhodotorula glutinis var. glutinis was isolated from the blood of two patients who were seriously ill and required long-term intravenous therapy. Although both isolates were sensitive to amphotericin B and 5-fluorocytosine, neither patient received antifungal therapy. One of the two patients died, but Rhodotorula was not recovered at autopsy. Review of the literature shows that Rhodotorula septicemia is often associated with contamination of intravenous infusion equipment, resulting in toxemia and hypotension. Initial therapy for fungemia should consist of removal of infected cannulas and fluid replacement. If fungemia persists, antifungal drug therapy should be considered.
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PMID:Rhodotorula septicemia: two cases and a review of the literature. 718 2

A 4-year study on maternal mortality in Muhumbili Medical Center in Dar es Salaam was conducted. One obstetrician assigned causes of deaths to all pregnant women who died in the centre since 1974, and the deaths were regularly discussed at special maternal mortality meetings. The results show that during the period of study, there has been a steady increase of hospital admissions due to abortions and deliveries, and a similar increase in death rates from deliveries. Overall mortality rate is 2./1000 deliveries, representing 224 maternal deaths out of a total of 105,311 deliveries and 11,534 abortions. The rate showed very little improvement year by year. The top 5 causes of death included toxemia of pregnancy; deaths associated with cesarian sections; anemia; sepsis (other than that associated with abortions); and postpartum hemorrhage. Direct obstetric causes accounted for 86% of all deaths. Avoidability of maternal deaths in this series rests perhaps with 3 main groups: the woman and her family; the maternity unit or institutions' personnel and facilities; and the national policy on maternal health and whether this is given any priority in the usually overstretched national budget.
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PMID:Maternal mortality in Dar Es Salaam, Tanzania, 1974-1977. 737 78

Percutaneous cholecystostomy offers a potentially important therapeutic modality for critically ill patients with acute cholecystitis who represent a high risk for general anaesthesia. The aim of the study was to assess experience with percutaneous cholecystostomy in resolving the acute episode of cholecystitis without operative intervention. Twenty-two consecutive patients with a clinical diagnosis of acute cholecystitis underwent the procedure. All were at high risk for general anaesthesia, and all but one developed cholecystitis while hospitalized for another co-morbid condition; 14 were in an intensive care unit. Twenty-one of the 22 patients proved to have acute cholecystitis (11 acalculous, ten cholelithiasis). There were no acute technical complications. Toxaemia resolved in 17 of the 21 patients with acute cholecystitis. Acute cholecystitis failed to resolve in three patients; all died within 48 h from overwhelming generalized sepsis. One patient required emergency cholecystectomy for bile peritonitis when the cholecystostomy catheter became dislodged 24 h after placement. The 60-day mortality rate for the acalculous and calculous patient groups was 55 and 20 per cent, respectively. Only three interval cholecystectomies have been performed at a mean follow-up of 19 months. In conclusion, percutaneous cholecystostomy may be the procedure of choice for the management of acute cholecystitis in the very high-risk critically ill patient. If symptoms fail to resolve quickly, ongoing sepsis, cholangitis or gallbladder necrosis should be suspected.
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PMID:Percutaneous cholecystostomy: a valuable technique in high-risk patients with presumed acute cholecystitis. 866 26


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