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Query: UMLS:C0036690 (sepsis)
 59,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Both neonates of male twins born at 30 weeks and 3 days gestation presented with late-onset sepsis caused by an infection with group B streptococci (GBS), shortly after one another. Although the younger twin recovered with a standard regimen of 10 days penicillin G i.v., the older twin had three recurrent episodes with GBS positive blood cultures. Oropharyngeal, faecal, urine, liquor and breast milk cultures were GBS negative. Using echocardiography and a PET/CT scan, a persistent endovascular focus was discovered. We treated him with penicillin G i.v. for 4 weeks, after which he recovered completely. Another male neonate born at 26 weeks gestation presented with GBS sepsis and developed an erythematous swelling of the right mandibula within 12 hours. Ultrasound revealed parotitis, which is rare in neonates (3.8 per 10,000). Risk factors for parotitis include prematurity, low birth weight and dehydration (i.e., diuretic usage). Parotitis can be complicated by abscess formation.
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PMID:[Neonatal sepsis caused by group B streptococci: atypical and recurrent disease episodes]. 2357 90

Common clinical presentations of melioidosis in children include suppurative parotitis, lymphadenitis, skin infection and septicemia with pneumonia. Here we describe three cases with uncommon presentations of melioidosis seen among children attending a university hospital in northeastern Thailand. Two patients presented with pharyngitis and subsequently developed cervical lymphadenitis. Another patient presented with high fever and generalized urticarial rash. A pharyngeal culture in each of the first 2 patients and a blood culture and culture of the discharge from the wound of the third patient grew Burkholderia pseudomallei. All patients recovered with treatment. Their clinical presentations, initial diagnosis, treatment, clinical course and outcomes are described. Physicians caring for children living in, or returning from, melioidosis endemic areas should be aware of these uncommon presentations.
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PMID:Uncommon clinical presentations of melioidosis in children: 2 cases with sore throat and 1 case with urticarial rash. 2443 21

Acute neonatal parotitis (ANP) is a very rare disease. Most cases are managed conservatively; early antibiotics and adequate hydration may reduce the need for surgery. The most common cause of ANP is Staphylococcus aureus. We report a rare case of acute neonatal parotitis with late-onset septic shock due to Streptococcus agalactiae. The diagnosis was confirmed with ultrasound and isolation of Streptococcus agalactiae from blood culture. The patient was treated successfully with 10 days of intravenous antibiotics and supportive measures. Despite being rare, streptococcal ANP should be considered in the etiological diagnosis of neonatal sepsis. Early diagnosis and appropriate antibiotic might prevent serious complications.
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PMID:Acute Neonatal Parotitis with Late-Onset Septic Shock due to Streptococcus agalactiae. 2465 47

Acute suppurative parotitis is a rare entity in neonates. Bilateral involvement is extremely rare. Low birth weight, prematurity, gavage feeding, dehydration, sepsis are all known risk factors. Staphylococcus aureus is the most common organism, other organisms responsible for parotitis are streptococcus, E. coli, pseudomonas and klebsiella. We report a neonate suffering from bilateral acute suppurative parotitis with an unusual causative association. CPAP and its association for acute suppurative parotitis has been proposed.
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PMID:Bilateral acute neonatal suppurative parotitis: A rare finding in neonatal age. 2575 1

Neonatal suppurative parotitis is a rare condition characterized by swelling, pain and erythema over the parotid gland. There may be a purulent exsudate from the Stensen duct. The predominant etiology is Staphylococcus aureus but cases with gram negative bacteria and streptococci have been reported. Most cases are managed conservatively with intravenous antibiotic therapy, and early treatment reduces risks of complications like sepsis and intraglandular abscess. We report two cases of neonatal suppurative parotitis; two 14-days-old males, both with one day history of parotid swelling and erythema. In one of them purulent exudate could be extracted from the Stensen duct. One of them had positive blood culture with Staphylococcus aureus. Ultrasound examination showed an enlarged parotid gland but no abscess. Growth of Staphylococcus aureus was found in both cases and the patients responded well to intravenous antibiotic therapy.
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PMID:[Neonatal suppurative parotitis]. 3179 49


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